Reduced Granule Cell Proliferation and Molecular Dysregulation in the Cerebellum of Lysosomal Acid Phosphatase 2 (ACP2) Mutant Mice.
Acid Phosphatase
/ genetics
Animals
Cell Differentiation
/ genetics
Cell Proliferation
/ genetics
Cerebellar Ataxia
/ genetics
Cerebellar Cortex
/ abnormalities
Cytoplasmic Granules
/ genetics
Disease Models, Animal
Gene Expression Regulation, Developmental
Hedgehog Proteins
/ genetics
Humans
Lysosomes
/ genetics
Mice
Mutation
N-Myc Proto-Oncogene Protein
/ genetics
Neurons
/ metabolism
Purkinje Cells
/ metabolism
Signal Transduction
/ genetics
MYCN
SHH
cerebellum
granule cells
mice
nax
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
15 Mar 2021
15 Mar 2021
Historique:
received:
27
01
2021
revised:
08
03
2021
accepted:
12
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
24
4
2021
Statut:
epublish
Résumé
Lysosomal acid phosphatase 2 (
Identifiants
pubmed: 33804256
pii: ijms22062994
doi: 10.3390/ijms22062994
pmc: PMC7999993
pii:
doi:
Substances chimiques
Hedgehog Proteins
0
MYCN protein, mouse
0
N-Myc Proto-Oncogene Protein
0
Shh protein, mouse
0
Acid Phosphatase
EC 3.1.3.2
Acp2 protein, mouse
EC 3.1.3.2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Natural Sciences and Engineering Research Council of Canada
ID : RGPIN-2018-06040
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