Aerobic Exercise and Stretching as Add-On to Inpatient Treatment for Depression Have No Differential Effects on Stress-Axis Activity, Serum-BDNF, TNF-Alpha and Objective Sleep Measures.

BDNF HPA-Axis aerobic exercise cardiorespiratory fitness depression randomized controlled trial sleep

Journal

Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646

Informations de publication

Date de publication:
24 Mar 2021
Historique:
received: 18 02 2021
revised: 19 03 2021
accepted: 20 03 2021
entrez: 3 4 2021
pubmed: 4 4 2021
medline: 4 4 2021
Statut: epublish

Résumé

(1) Background: While the antidepressant effects of aerobic exercise (AE) are well documented, fewer studies have examined impact of AE as an add-on treatment. Moreover, various effects on neurobiological variables have been suggested. This study examines effects of AE on Cortisol Awakening Reaction (CAR), serum Brain Derived Neurotrophic Factor (sBDNF), Tumor Necrosis Factor alpha (TNF-alpha) and sleep. (2) Methods: Inpatients with moderate-to-severe depression (

Identifiants

pubmed: 33805073
pii: brainsci11040411
doi: 10.3390/brainsci11040411
pmc: PMC8064092
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Gottfried und Julia Bangerter-Rhyner-Stiftung
ID : 2013
Organisme : Helsana health insurance company
ID : 2013
Organisme : Canton of Solothurn
ID : 2013

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Auteurs

Christian Imboden (C)

Psychiatric Services Solothurn, 4503 Solothurn, Switzerland and University of Basel, 4031 Basel, Switzerland.
Private Clinic Wyss, 3053 Muenchenbuchsee, Switzerland.

Markus Gerber (M)

Department of Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.

Johannes Beck (J)

Psychiatric University Hospital, University of Basel, 4031 Basel, Switzerland.
Private Clinic Sonnenhalde, 4125 Riehen, Switzerland.

Anne Eckert (A)

Psychiatric University Hospital, University of Basel, 4031 Basel, Switzerland.

Imane Lejri (I)

Psychiatric University Hospital, University of Basel, 4031 Basel, Switzerland.

Uwe Pühse (U)

Department of Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.

Edith Holsboer-Trachsler (E)

Psychiatric University Hospital, University of Basel, 4031 Basel, Switzerland.

Martin Hatzinger (M)

Psychiatric Services Solothurn, 4503 Solothurn, Switzerland and University of Basel, 4031 Basel, Switzerland.

Classifications MeSH