Impact of Probiotics on the Salivary Microbiota and Salivary Levels of Inflammation-Related Proteins during Short-Term Sugar Stress: A Randomized Controlled Trial.
16S rDNA
homeostasis
oral microbiota
sugar stress
Journal
Pathogens (Basel, Switzerland)
ISSN: 2076-0817
Titre abrégé: Pathogens
Pays: Switzerland
ID NLM: 101596317
Informations de publication
Date de publication:
25 Mar 2021
25 Mar 2021
Historique:
received:
02
03
2021
revised:
18
03
2021
accepted:
22
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
4
4
2021
Statut:
epublish
Résumé
The purpose of the present investigation was to characterize the effect of probiotics on the composition of the salivary microbiota and salivary levels of inflammation-related proteins during short-term sugar stress. We tested the hypotheses that consumption of probiotics may partly counteract the detrimental influence of sugar stress on oral homeostasis. The present study was a five-week, blinded, randomized controlled trial with four study arms-A: sucrose and probiotic ( Sugar stress induced a significant increase in the relative abundance of the genus The data clearly demonstrate an impact of combined consumption of xylitol and probiotics on the composition of the salivary microbiota. Future studies are needed to evaluate whether the combined use of xylitol and the probiotic strains tested could have clinically protective effects during periods of sugar stress.
Sections du résumé
BACKGROUND
BACKGROUND
The purpose of the present investigation was to characterize the effect of probiotics on the composition of the salivary microbiota and salivary levels of inflammation-related proteins during short-term sugar stress. We tested the hypotheses that consumption of probiotics may partly counteract the detrimental influence of sugar stress on oral homeostasis.
METHODS
METHODS
The present study was a five-week, blinded, randomized controlled trial with four study arms-A: sucrose and probiotic (
RESULTS
RESULTS
Sugar stress induced a significant increase in the relative abundance of the genus
CONCLUSIONS
CONCLUSIONS
The data clearly demonstrate an impact of combined consumption of xylitol and probiotics on the composition of the salivary microbiota. Future studies are needed to evaluate whether the combined use of xylitol and the probiotic strains tested could have clinically protective effects during periods of sugar stress.
Identifiants
pubmed: 33805894
pii: pathogens10040392
doi: 10.3390/pathogens10040392
pmc: PMC8064398
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Sundhed og Sygdom, Det Frie Forskningsråd
ID : n.a
Organisme : Deerland Probiotics and Enzymes A/S
ID : n.a
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