Adverse Prognostic Impact of the

Adult Aged Aged, 80 and over Amino Acid Substitution Bone Marrow / metabolism DNA / blood Female Gene Frequency Humans Male Mastocytosis, Systemic / blood Middle Aged Mutation Phenotype Prognosis Proto-Oncogene Proteins c-kit / genetics RNA / blood Transcription, Genetic
KIT D816V advanced SM allele burden survival variant allele frequency

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
04 Mar 2021
Historique:
received: 04 02 2021
revised: 25 02 2021
accepted: 26 02 2021
entrez: 3 4 2021
pubmed: 4 4 2021
medline: 27 4 2021
Statut: epublish

Résumé

In systemic mastocytosis (SM), qualitative and serial quantitative assessment of the

Identifiants

DOI: 10.3390/ijms22052562 PMID: 33806359 PMC: PMC7961551
pubmed: 33806359
pii: ijms22052562
doi: 10.3390/ijms22052562
pmc: PMC7961551
pii:
doi:

Substances chimiques

RNA 63231-63-0
DNA 9007-49-2
KIT protein, human EC 2.7.10.1
Proto-Oncogene Proteins c-kit EC 2.7.10.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : José Carreras Leukämie-Stiftung
ID : DJCLS 01R/2018 and DJCLS-08R/2020

Références

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Allergy. 2020 Jun;75(6):1489-1491
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pubmed: 28702366
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pubmed: 27196380
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pubmed: 23349688
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Clin Chem. 2018 Mar;64(3):547-555
pubmed: 29237714
Lancet Haematol. 2019 Dec;6(12):e638-e649
pubmed: 31676322
Leukemia. 2016 Dec;30(12):2342-2350
pubmed: 27416984
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pubmed: 33337831
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pubmed: 30536695
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pubmed: 31509472
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pubmed: 27069254
Leukemia. 2016 Jan;30(1):136-43
pubmed: 26464169
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pubmed: 21354053
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pubmed: 30911112
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pubmed: 28424161
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pubmed: 25582384
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pubmed: 24173087
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pubmed: 28031180

Auteurs

Nicole Naumann (N)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Johannes Lübke (J)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Sofie Baumann (S)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Juliana Schwaab (J)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
ORCID: 0000-0001-9208-5264

Oliver Hoffmann (O)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Sebastian Kreil (S)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Vito Dangelo (V)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Lukas Reiter (L)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Peter Bugert (P)

Institute of Transfusion Medicine and Immunology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Thomas Kristensen (T)

Mastocytosis Center, Odense University Hospital, 5000 Odense, Denmark.
Department of Pathology, Odense University Hospital, 5000 Odense, Denmark.

Karl Sotlar (K)

University Hospital Salzburg, Paracelsus Medical University, 5020 Salzburg, Austria.

Verena Haselmann (V)

Institute for Clinical Chemistry, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Sven Schneider (S)

Institute for Clinical Chemistry, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Georgia Metzgeroth (G)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Christel Weiss (C)

Department of Medical Statistics and Biomathematics, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Henning D Popp (HD)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
ORCID: 0000-0003-0090-0204

Alice Fabarius (A)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Wolf-Karsten Hofmann (WK)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Nicholas C P Cross (NCP)

School of Medicine, University of Southampton, Southampton SO17 1BJ, UK.
Wessex Regional Genetics Laboratory, Salisbury SP2 8BJ, UK.
ORCID: 0000-0001-5481-2555

Andreas Reiter (A)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Mohamad Jawhar (M)

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.
ORCID: 0000-0001-9148-9398

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adverse Prognostic Impact of the
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Adverse Prognostic Impact of the
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Sujet âgé de 80 ans ou plus › Adverse Prognostic Impact of the
questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Substitution d'acide aminé › Adverse Prognostic Impact of the
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Moelle osseuse › Adverse Prognostic Impact of the
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › Adverse Prognostic Impact of the
questionsmedicales.fr › Phénomènes génétiques › Fréquence d'allèle › Adverse Prognostic Impact of the
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Adverse Prognostic Impact of the
questionsmedicales.fr › Maladies du système immunitaire › Troubles de l'activation mastocytaire › Mastocytose › Mastocytose généralisée › Adverse Prognostic Impact of the
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Adverse Prognostic Impact of the
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Adverse Prognostic Impact of the
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Adverse Prognostic Impact of the
questionsmedicales.fr › Diagnostic › Pronostic › Adverse Prognostic Impact of the
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › Protéines oncogènes › Protéines proto-oncogènes › Protéines proto-oncogènes c-kit › Adverse Prognostic Impact of the
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › Adverse Prognostic Impact of the
questionsmedicales.fr › Phénomènes génétiques › Expression des gènes › Transcription génétique › Adverse Prognostic Impact of the