Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq.
Hfq
antibacterial compound
apomorphine
bacterial adaptation
bacterial amyloid
functional amyloid
protein fibrillation inhibition
protein fibrils
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
04 Mar 2021
04 Mar 2021
Historique:
received:
31
01
2021
revised:
24
02
2021
accepted:
27
02
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
4
4
2021
Statut:
epublish
Résumé
Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance for bacterial adaptation and survival in hosts. Small RNAs and Hfq are, for instance, involved in the response to antibiotics. Previous work has shown that the
Identifiants
pubmed: 33806663
pii: antibiotics10030257
doi: 10.3390/antibiotics10030257
pmc: PMC8000489
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Centre National de la Recherche Scientifique
ID : IEA/PICS 08254
Organisme : ECOS
ID : action n°C19S02
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