Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges.

laser elemental analysis laser machining laser printing laser-assisted methods nanomedicine nanoparticles tissue engineering

Journal

Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216

Informations de publication

Date de publication:
12 Mar 2021
Historique:
received: 03 02 2021
revised: 04 03 2021
accepted: 08 03 2021
entrez: 3 4 2021
pubmed: 4 4 2021
medline: 4 4 2021
Statut: epublish

Résumé

Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to directly structure matter at different scales and to prepare novel materials with unique physical and chemical properties. It is also a contact-free approach that makes it possible to work in inert or reactive liquid or gaseous environment. This leads today to a unique opportunity for designing, fabricating and even analyzing novel complex bio-systems. To illustrate this potential, in this paper, we gather our recent research on four types of laser-based methods relevant for nano-/micro-scale applications. First, we present and discuss pulsed laser ablation in liquid, exploited today for synthetizing ultraclean "bare" nanoparticles attractive for medicine and tissue engineering applications. Second, we discuss robust methods for rapid surface and bulk machining (subtractive manufacturing) at different scales by laser ablation. Among them, the microsphere-assisted laser surface engineering is detailed for its appropriateness to design structured substrates with hierarchically periodic patterns at nano-/micro-scale without chemical treatments. Third, we address the laser-induced forward transfer, a technology based on direct laser printing, to transfer and assemble a multitude of materials (additive structuring), including biological moiety without alteration of functionality. Finally, the fourth method is about chemical analysis: we present the potential of laser-induced breakdown spectroscopy, providing a unique tool for contact-free and space-resolved elemental analysis of organic materials. Overall, we present and discuss the prospect and complementarity of emerging reliable laser technologies, to address challenges in materials' preparation relevant for the development of innovative multi-scale and multi-material platforms for bio-applications.

Identifiants

pubmed: 33809072
pii: nano11030712
doi: 10.3390/nano11030712
pmc: PMC8001552
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Ahmed Al-Kattan (A)

Aix-Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, Case 917, CEDEX 09, 13288 Marseille, France.

David Grojo (D)

Aix-Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, Case 917, CEDEX 09, 13288 Marseille, France.

Christophe Drouet (C)

CIRIMAT, Université de Toulouse, UMR 5085 CNRS/Toulouse INP/UT3 Paul Sabatier, Ensiacet, 4 allée E. Monso, CEDEX 04, 31030 Toulouse, France.

Alexandros Mouskeftaras (A)

Aix-Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, Case 917, CEDEX 09, 13288 Marseille, France.

Philippe Delaporte (P)

Aix-Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, Case 917, CEDEX 09, 13288 Marseille, France.

Adrien Casanova (A)

Aix-Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, Case 917, CEDEX 09, 13288 Marseille, France.

Jérôme D Robin (JD)

Aix-Marseille University, INSERM, MMG, Marseille Medical Genetics, 13385 Marseille, France.

Frédérique Magdinier (F)

Aix-Marseille University, INSERM, MMG, Marseille Medical Genetics, 13385 Marseille, France.

Patricia Alloncle (P)

Aix-Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, Case 917, CEDEX 09, 13288 Marseille, France.

Catalin Constantinescu (C)

Aix-Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, Case 917, CEDEX 09, 13288 Marseille, France.

Vincent Motto-Ros (V)

Institut Lumière Matière UMR 5306, Université Lyon 1-CNRS, Université de Lyon, 69622 Villeurbanne, France.

Jörg Hermann (J)

Aix-Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, Case 917, CEDEX 09, 13288 Marseille, France.

Classifications MeSH