Prokineticin receptors interact unselectively with several G protein subtypes but bind selectively to β-arrestin 2.
Bioluminescence resonance energy tranfer (BRET)
G-protein coupled receptor (GPCR)
Prokineticins
β-Arrestin
Journal
Cellular signalling
ISSN: 1873-3913
Titre abrégé: Cell Signal
Pays: England
ID NLM: 8904683
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
03
03
2021
revised:
29
03
2021
accepted:
30
03
2021
pubmed:
4
4
2021
medline:
20
1
2022
entrez:
3
4
2021
Statut:
ppublish
Résumé
Prokineticin 1 (pk1) and prokineticin 2 (pk2) interact with two structurally related G-protein coupled receptors, prokineticin receptor 1 (PKR1) and prokineticin receptor 2 (PKR2). Cellular signalling studies show that the activated receptors can evoke Ca
Identifiants
pubmed: 33811988
pii: S0898-6568(21)00088-7
doi: 10.1016/j.cellsig.2021.110000
pii:
doi:
Substances chimiques
ARRB2 protein, human
0
Arrb2 protein, mouse
0
PKR1 protein, mouse
0
PKR2 protein, mouse
0
PROKR1 protein, human
0
PROKR2 protein, human
0
Receptors, G-Protein-Coupled
0
Receptors, Peptide
0
beta-Arrestin 2
0
Cyclic AMP
E0399OZS9N
GTP-Binding Proteins
EC 3.6.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
110000Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.