Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R.
GCAP
GUCA1B
cGMP
calcium-binding proteins
guanylate cyclase (guanylyl cyclase)
neurodegenerative disease
phototransduction
retina
retinal degeneration
vision
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
Historique:
received:
13
02
2021
revised:
25
03
2021
accepted:
30
03
2021
pubmed:
5
4
2021
medline:
21
8
2021
entrez:
4
4
2021
Statut:
ppublish
Résumé
In murine and bovine photoreceptors, guanylate cyclase-activating protein 2 (GCAP2) activates retinal guanylate cyclases (GCs) at low Ca
Identifiants
pubmed: 33812995
pii: S0021-9258(21)00404-X
doi: 10.1016/j.jbc.2021.100619
pmc: PMC8113879
pii:
doi:
Substances chimiques
GUCA1B protein, human
0
Guanylate Cyclase-Activating Proteins
0
Magnesium
I38ZP9992A
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
100619Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest The authors declare that they have no conflicts of interest with the contents of this article.
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