Prenatal exposure to criteria air pollutants and associations with congenital anomalies: A Lebanese national study.

Air Pollutants / analysis Air Pollution / analysis Case-Control Studies Female Humans Maternal Exposure Particulate Matter Pregnancy Prenatal Exposure Delayed Effects / epidemiology
Air pollution Congenital anomalies Eastern Mediterranean Region (EMR) Machine learning Neonatal health

Journal

Environmental pollution (Barking, Essex : 1987)
ISSN: 1873-6424
Titre abrégé: Environ Pollut
Pays: England
ID NLM: 8804476

Informations de publication

Date de publication:
15 Jul 2021
Historique:
received: 20 08 2020
revised: 19 02 2021
accepted: 22 03 2021
pubmed: 5 4 2021
medline: 2 6 2021
entrez: 4 4 2021
Statut: ppublish

Résumé

Maternal exposure to air pollution has been associated with a higher birth defect (BD) risk. Previous studies suffer from inaccurate exposure assessment methods, confounding individual-level variations, and classical analytical modelling. This study aimed to examine the association between maternal exposure to criteria air pollutants and BD risk. A total of 553 cases and 10,214 controls were identified from private and public databases. Two subgroups were then formed: one for a matched case-control design, and another for Feature Selection (FS) analysis. Exposure assessment was based on the mean air pollutant-specific levels in the mother's residential area during the specific BD gestational time window of risk (GTWR) and other time intervals. Multivariate regression models outcomes consistently showed a significant protective effect for folic acid intake and highlighted parental consanguinity as a strong BD risk factor. After adjusting for these putative risk factors and other covariates, results show that maternal exposure to PM

Identifiants

DOI: 10.1016/j.envpol.2021.117022 PMID: 33813197
pubmed: 33813197
pii: S0269-7491(21)00604-7
doi: 10.1016/j.envpol.2021.117022
pii:
doi:

Substances chimiques

Air Pollutants 0
Particulate Matter 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

117022

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Ghaliya Al Noaimi (G)

Department of Environmental Health, Faculty of Health Sciences, American University of Beirut, Lebanon. Electronic address: gaa44@mail.aub.edu.

Khalid Yunis (K)

Department of Pediatrics and Adolescent Medicine, Faculty of Medicine, American University of Beirut, Lebanon. Electronic address: kayunis@aub.edu.lb.

Khalil El Asmar (K)

Department of Epidemiology and Population Health, Faculty of Health Sciences, American University of Beirut, Lebanon. Electronic address: ke05@aub.edu.lb.

Fatima K Abu Salem (FK)

Department of Computer Science, Faculty of Arts and Sciences, American University of Beirut, Lebanon. Electronic address: fa21@aub.edu.lb.

Charbel Afif (C)

EMMA Laboratory, Center for Analysis and Research, Faculty of Science, Saint-Joseph University, Beirut, Lebanon; Climate and Atmosphere Research Center, The Cyprus Institute, Nicosia, Cyprus. Electronic address: charbel.afif@usj.edu.lb.

Lilian A Ghandour (LA)

Department of Epidemiology and Population Health, Faculty of Health Sciences, American University of Beirut, Lebanon. Electronic address: lg01@aub.edu.lb.

Ahmad Hamandi (A)

Department of Computer Science, Faculty of Arts and Sciences, American University of Beirut, Lebanon. Electronic address: amh61@mail.aub.edu.

Hassan R Dhaini (HR)

Department of Environmental Health, Faculty of Health Sciences, American University of Beirut, Lebanon. Electronic address: hd24@aub.edu.lb.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants atmosphériques › Prenatal exposure to criteria air pollutants...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Pollution de l'air › Prenatal exposure to criteria air pollutants...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études cas-témoins › Prenatal exposure to criteria air pollutants...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Prenatal exposure to criteria air pollutants...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Exposition environnementale › Exposition maternelle › Prenatal exposure to criteria air pollutants...
questionsmedicales.fr › Mélanges complexes › Matière particulaire › Prenatal exposure to criteria air pollutants...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Prenatal exposure to criteria air pollutants...
questionsmedicales.fr › Maladies urogénitales › Maladies de l'appareil urogénital féminin et complications de la grossesse › Complications de la grossesse › Lésions prénatales › Effets différés de l'exposition prénatale à des facteurs de risque › Prenatal exposure to criteria air pollutants...