Value of Panendoscopy in the Identification of Synchronous Malignancies in Patients Suffering from Oral Squamous Cell Carcinoma Without Clinical Signs of a Second Primary Tumor.
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell
/ diagnosis
Diagnosis, Differential
Endoscopy, Digestive System
/ methods
Female
Humans
Male
Middle Aged
Mouth Neoplasms
/ diagnosis
Neoplasms, Multiple Primary
/ diagnosis
Neoplasms, Second Primary
/ diagnosis
Predictive Value of Tests
Retrospective Studies
Panendoscopy
head and neck cancer
oral squamous cell carcinoma
staging
synchronous malignancy
Journal
Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
18
01
2021
revised:
24
02
2021
accepted:
25
02
2021
entrez:
4
4
2021
pubmed:
5
4
2021
medline:
28
4
2021
Statut:
ppublish
Résumé
The aim of the present study was to assess the value of panendoscopy of the upper aero-digestive tract in the identification of synchronous tumors in OSCC patients without clinical signs of a second primary tumor. In this retrospective study, patients diagnosed with a primary OSCC who received surgical therapy between January 1 A total of 265 patients (99 females and 166 males; mean age=63.3 years, range=26-96 years) were included. The mean (SD) follow-up was 25.88 (±20.479 SD) months. Five synchronous secondary tumors (1.9%) could be identified within this cohort. Of these, only two (0.8%) were located within the area of panendoscopy and were diagnosed in patients with regular alcohol and/or tobacco abuse. Eighteen metachronous second primary tumors were diagnosed, 10 being located within the upper aero-digestive tract. The relevance of routinely performed panendoscopy in patients suffering from an oral squamous cell carcinoma without clinical signs of a secondary tumor should be critically re-evaluated, especially in patients without typical risk factors.
Sections du résumé
BACKGROUND/AIM
OBJECTIVE
The aim of the present study was to assess the value of panendoscopy of the upper aero-digestive tract in the identification of synchronous tumors in OSCC patients without clinical signs of a second primary tumor.
PATIENTS AND METHODS
METHODS
In this retrospective study, patients diagnosed with a primary OSCC who received surgical therapy between January 1
RESULTS
RESULTS
A total of 265 patients (99 females and 166 males; mean age=63.3 years, range=26-96 years) were included. The mean (SD) follow-up was 25.88 (±20.479 SD) months. Five synchronous secondary tumors (1.9%) could be identified within this cohort. Of these, only two (0.8%) were located within the area of panendoscopy and were diagnosed in patients with regular alcohol and/or tobacco abuse. Eighteen metachronous second primary tumors were diagnosed, 10 being located within the upper aero-digestive tract.
CONCLUSION
CONCLUSIONS
The relevance of routinely performed panendoscopy in patients suffering from an oral squamous cell carcinoma without clinical signs of a secondary tumor should be critically re-evaluated, especially in patients without typical risk factors.
Identifiants
pubmed: 33813411
pii: 41/4/2039
doi: 10.21873/anticanres.14972
doi:
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2039-2044Informations de copyright
Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.