Inflammatory Pseudotumor Resembling a Malignant Pancreatic Disease Process.


Journal

Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 28 02 2021
revised: 14 03 2021
accepted: 16 03 2021
entrez: 4 4 2021
pubmed: 5 4 2021
medline: 10 4 2021
Statut: ppublish

Résumé

Inflammatory pseudotumors are complex entities given that they carry varying characteristics with a multitude of behaviors that can resemble a malignancy clinically, radiographically, and histologically. Our case report presents a 65-year-old-female with a history of fever, abdominal pain, and anemia with imaging suggestive of a malignant disease process involving an ill-defined soft tissue mass between the left adrenal gland and pancreatic tail. Following diagnostic laparoscopy with abdominal washings and subsequent open resection of the mass, final pathology revealed multiple specimens demonstrating dense fibrosis with admixed spindled cells and inflammatory cells, an overarching morphology, and an immunohistochemical staining profile consistent with pancreatic inflammatory pseudotumor. Inflammatory pseudotumor is a challenging diagnosis and should be included in the differential diagnosis for a patient who presents with nonspecific symptoms and an ill-defined mass on imaging.

Sections du résumé

BACKGROUND/AIM OBJECTIVE
Inflammatory pseudotumors are complex entities given that they carry varying characteristics with a multitude of behaviors that can resemble a malignancy clinically, radiographically, and histologically.
PATIENTS AND METHODS METHODS
Our case report presents a 65-year-old-female with a history of fever, abdominal pain, and anemia with imaging suggestive of a malignant disease process involving an ill-defined soft tissue mass between the left adrenal gland and pancreatic tail.
RESULTS RESULTS
Following diagnostic laparoscopy with abdominal washings and subsequent open resection of the mass, final pathology revealed multiple specimens demonstrating dense fibrosis with admixed spindled cells and inflammatory cells, an overarching morphology, and an immunohistochemical staining profile consistent with pancreatic inflammatory pseudotumor.
CONCLUSION CONCLUSIONS
Inflammatory pseudotumor is a challenging diagnosis and should be included in the differential diagnosis for a patient who presents with nonspecific symptoms and an ill-defined mass on imaging.

Identifiants

pubmed: 33813417
pii: 41/4/2079
doi: 10.21873/anticanres.14978
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2079-2082

Informations de copyright

Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Auteurs

Jamie Kaplan (J)

Department of General Surgery, Mayo Clinic, Jacksonville, FL, U.S.A. Kaplan.jamie@mayo.edu.

Catherine Mangum (C)

Department of General Surgery, Mayo Clinic, Jacksonville, FL, U.S.A.

Mira Shoukry (M)

Department of General Surgery, Mayo Clinic, Jacksonville, FL, U.S.A.

Emmanuel Gabriel (E)

Department of General Surgery, Mayo Clinic, Jacksonville, FL, U.S.A.

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Classifications MeSH