Corneal Cross-linking as an Adjunct for The Management of Refractory Fungal Keratitis.
Adult
Aged
Collagen
/ metabolism
Corneal Stroma
/ metabolism
Corneal Ulcer
/ drug therapy
Cross-Linking Reagents
Eye Infections, Fungal
/ drug therapy
Humans
Male
Middle Aged
Photochemotherapy
/ methods
Photosensitizing Agents
/ therapeutic use
Prospective Studies
Riboflavin
/ therapeutic use
Slit Lamp Microscopy
Ultraviolet Rays
Corneal cross-linking
fungal
keratitis
ultraviolet-A/riboflavin
Journal
Middle East African journal of ophthalmology
ISSN: 0975-1599
Titre abrégé: Middle East Afr J Ophthalmol
Pays: India
ID NLM: 101521797
Informations de publication
Date de publication:
Historique:
received:
20
05
2019
revised:
15
04
2020
accepted:
19
09
2020
entrez:
5
4
2021
pubmed:
6
4
2021
medline:
29
5
2021
Statut:
epublish
Résumé
To evaluate the effectiveness of ultraviolet (UV)-A/Riboflavin corneal cross-linking (CXL) for the treatment of the refractory cases of fungal keratitis. In this prospective interventional study, 9 patients with the diagnosis of fungal keratitis that were referred to our emergency eye center were included. These patients were resistant to conventional treatment and underwent therapeutic UV-A/Riboflavin CXL. Response to the treatment was considered as good if rapid epithelialization and rapid decrease in stromal infiltration was occurred after PACK-CXL, and poor when the emergency transplantation was necessary to eradicate the infection. Nine patients treated with CXL due to recalcitrant fungal keratitis. Culture of the corneal scrapings showed Although UV-A/Riboflavin CXL is not a definite treatment for all of the fungal keratitis, it seems promising in the management of some refractory cases.
Identifiants
pubmed: 33814816
doi: 10.4103/meajo.MEAJO_130_19
pii: MEAJO-27-204
pmc: PMC7993049
doi:
Substances chimiques
Cross-Linking Reagents
0
Photosensitizing Agents
0
Collagen
9007-34-5
Riboflavin
TLM2976OFR
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
204-209Informations de copyright
Copyright: © 2021 Middle East African Journal of Ophthalmology.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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