Continuous Infusion of Flumazenil in the Management of Benzodiazepines Detoxification.
benzodiazepine
detoxifcation
flumazenil
high dose
withdrawal
Journal
Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006
Informations de publication
Date de publication:
2021
2021
Historique:
received:
24
12
2020
accepted:
15
02
2021
entrez:
5
4
2021
pubmed:
6
4
2021
medline:
6
4
2021
Statut:
epublish
Résumé
An effective approach in the treatment of benzodiazepine (BZD) overdosing and detoxification is flumazenil (FLU). Studies in chronic users who discontinued BZD in a clinical setting suggested that multiple slow bolus infusions of FLU reduce BZD withdrawal symptoms. The aim of this study was to confirm FLU efficacy for reducing BZD withdrawal syndrome by means of continuous elastomeric infusion, correlated to drugs plasma level and patients' compliance.
Identifiants
pubmed: 33815177
doi: 10.3389/fpsyt.2021.646038
pmc: PMC8012511
doi:
Types de publication
Journal Article
Langues
eng
Pagination
646038Informations de copyright
Copyright © 2021 Benini, Gottardo, Chiamulera, Bertoldi, Zamboni and Lugoboni.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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