Effects of coronary revascularization by elective percutaneous coronary intervention on cardiac autonomic modulation assessed by heart rate variability: a single-center prospective cohort study.

Coronary artery disease autonomic modulation complete revascularization coronary revascularization heart rate variability major adverse cardiovascular and cerebrovascular events percutaneous coronary intervention residual syntax score syntax score

Journal

American journal of cardiovascular disease
ISSN: 2160-200X
Titre abrégé: Am J Cardiovasc Dis
Pays: United States
ID NLM: 101569582

Informations de publication

Date de publication:
2021
Historique:
received: 24 12 2020
accepted: 29 01 2021
entrez: 5 4 2021
pubmed: 6 4 2021
medline: 6 4 2021
Statut: epublish

Résumé

To study the effects of coronary revascularization using elective percutaneous coronary intervention (PCI) on autonomic modulation assessed by heart rate variability measurement (HRV) in coronary artery disease (CAD) patients. A single-center prospective cohort study included 100 patients were included undergoing elective PCI excluding those with contraindication to contrast or dual antiplatelet therapy, atrial fibrillation or multiple premature beats, receiving anti-arrhythmic drugs and those who underwent previous PCI or coronary artery bypass graft (CABG). Short-term measurement of time domain parameters (mean, SDNN, RMSSD) and frequency domain parameters (LF component, HF component, LF/HF ratio) of HRV was performed at the same time of the day, pre-PCI, 24 hours and 6 months post-PCI by CheckMyheart™ handheld HRV device. 5-min HRV analysis software was used to interpret the data using standard methods of HRV measurement of the Task Force of The European Society of Cardiology (ESC) and The North American Society of Pacing and Electrophysiology. SYNTAX (SX) score was calculated before PCI and residual SYNTAX (rSS) score was calculated after PCI using SYNTAX score calculator software. The mean age of the studied population was 56.89±10.75 years with 85% males. HRV time and frequency domain parameters showed a statistically significant improvement at different time intervals (before PCI, 24 hours and 6 months after PCI) ( Autonomic modulation in CAD patients was improved by coronary revascularization using PCI assessed by serial HRV measurement. Patients with CR had better autonomic modulation than those with IR assessed by HRV 24 and 6 months after PCI.

Identifiants

pubmed: 33815932
pmc: PMC8012296

Types de publication

Journal Article

Langues

eng

Pagination

164-175

Informations de copyright

AJCD Copyright © 2021.

Déclaration de conflit d'intérêts

None.

Références

Circ J. 2012;76(7):1624-30
pubmed: 22504125
J Tehran Heart Cent. 2015 Apr 3;10(2):80-4
pubmed: 26110006
Clin Med Insights Cardiol. 2016 Mar 09;10:29-35
pubmed: 26997875
Cochrane Database Syst Rev. 2017 May 03;5:CD011986
pubmed: 28470696
EuroIntervention. 2017 May 15;13(1):97-105
pubmed: 28242583
Crit Care. 2016 Jun 11;20(1):179
pubmed: 27286655
Anatol J Cardiol. 2015 Jun;15(6):496-501
pubmed: 25550177
EuroIntervention. 2017 Nov 20;13(10):1185-1193
pubmed: 28760723
Cardiovasc J Afr. 2009 Jul-Aug;20(4):240-4
pubmed: 19701536
J Korean Med Sci. 2014 Nov;29(11):1501-6
pubmed: 25408581
Front Endocrinol (Lausanne). 2014 Aug 08;5:130
pubmed: 25152747
Int J Cardiol. 2017 Sep 15;243:21-26
pubmed: 28532984
J Intern Med. 2004 Jan;255(1):13-21
pubmed: 14687234
Circulation. 1996 Mar 1;93(5):1043-65
pubmed: 8598068
Am J Cardiol. 2000 Apr 1;85(7):815-20
pubmed: 10758919
Vasc Health Risk Manag. 2014 Aug 05;10:451-64
pubmed: 25143740
Catheter Cardiovasc Interv. 2015 Jul;86(1):3-10
pubmed: 25413668
Clin Cardiol. 2010 Jun;33(6):E16-21
pubmed: 20552589
Europace. 2013 May;15(5):742-9
pubmed: 23370966
J Am Coll Cardiol. 2012 Jun 12;59(24):2165-74
pubmed: 22483327
J Invasive Cardiol. 2004 Mar;16(3):102-6
pubmed: 15152155
Heart. 2006 Aug;92(8):1055-63
pubmed: 16387812
Przegl Lek. 2002;59(9):695-8
pubmed: 12632888
EuroIntervention. 2016 Oct 10;12(8):e957-e963
pubmed: 26690316

Auteurs

Mahmoud Abdelnabi (M)

Cardiology and Angiology Unit, Clinical and Experimental Internal Medicine Department, Medical Research Institute, Alexandria University Alexandria, Egypt.

Moataz Zaki (M)

Cardiology and Angiology Unit, Clinical and Experimental Internal Medicine Department, Medical Research Institute, Alexandria University Alexandria, Egypt.

Mohamed Sadaka (M)

Cardiology Department, Faculty of Medicine, Alexandria University Alexandria, Egypt.

Moustafa Nawar (M)

Cardiology Department, Faculty of Medicine, Alexandria University Alexandria, Egypt.

Classifications MeSH