Deep learning based fully automatic segmentation of the left ventricular endocardium and epicardium from cardiac cine MRI.

Deep learning left ventricle segmentation (LV segmentation) wall thickness

Journal

Quantitative imaging in medicine and surgery
ISSN: 2223-4292
Titre abrégé: Quant Imaging Med Surg
Pays: China
ID NLM: 101577942

Informations de publication

Date de publication:
Apr 2021
Historique:
entrez: 5 4 2021
pubmed: 6 4 2021
medline: 6 4 2021
Statut: ppublish

Résumé

The segmentation of cardiac medical images is a crucial step for calculating clinical indices such as wall thickness, ventricular volume, and ejection fraction. In this study, we introduce a method named LsUnet that combines multi-channel, fully convolutional neural network, and annular shape level-set methods for efficiently segmenting cardiac cine magnetic resonance (MR) images. In this method, the multi-channel deep learning algorithm is applied to train the segmentation task to extract the left ventricle (LV) endocardial and epicardial contours. Next, the segmentation contours from the multi-channel deep learning method are incorporated into a level-set formulation, which is dedicated explicitly to detecting annular shapes to assure the segmentation's accuracy and robustness. The proposed automatic approach was evaluated on 95 volumes (total 1,076 slices, ~80% as for training datasets, ~20% 2D as for testing datasets). This combined multi-channel deep learning and annular shape level-set segmentation method achieved high accuracy with average Dice values reaching 92.15% and 95.42% for LV endocardium and epicardium delineation, respectively, in comparison to the reference standard (the manual segmentation). A novel method for fully automatic segmentation of the LV endocardium and epicardium from different MRI datasets is presented. The proposed workflow is accurate and robust compared to the reference and other state-of-the-art methods.

Sections du résumé

BACKGROUND BACKGROUND
The segmentation of cardiac medical images is a crucial step for calculating clinical indices such as wall thickness, ventricular volume, and ejection fraction.
METHODS METHODS
In this study, we introduce a method named LsUnet that combines multi-channel, fully convolutional neural network, and annular shape level-set methods for efficiently segmenting cardiac cine magnetic resonance (MR) images. In this method, the multi-channel deep learning algorithm is applied to train the segmentation task to extract the left ventricle (LV) endocardial and epicardial contours. Next, the segmentation contours from the multi-channel deep learning method are incorporated into a level-set formulation, which is dedicated explicitly to detecting annular shapes to assure the segmentation's accuracy and robustness.
RESULTS RESULTS
The proposed automatic approach was evaluated on 95 volumes (total 1,076 slices, ~80% as for training datasets, ~20% 2D as for testing datasets). This combined multi-channel deep learning and annular shape level-set segmentation method achieved high accuracy with average Dice values reaching 92.15% and 95.42% for LV endocardium and epicardium delineation, respectively, in comparison to the reference standard (the manual segmentation).
CONCLUSIONS CONCLUSIONS
A novel method for fully automatic segmentation of the LV endocardium and epicardium from different MRI datasets is presented. The proposed workflow is accurate and robust compared to the reference and other state-of-the-art methods.

Identifiants

pubmed: 33816194
doi: 10.21037/qims-20-169
pii: qims-11-04-1600
pmc: PMC7930660
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1600-1612

Subventions

Organisme : NIBIB NIH HHS
ID : K25 EB014914
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL114118
Pays : United States
Organisme : NHLBI NIH HHS
ID : R56 HL133663
Pays : United States

Informations de copyright

2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/qims-20-169). The authors have no conflicts of interest to declare.

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Auteurs

Yan Wang (Y)

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, USA.

Yue Zhang (Y)

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, USA.
Department of Radiology, Veterans Affairs Medical Center, San Francisco, USA.

Zhaoying Wen (Z)

Department of Radiology, Anzhen Hospital, Beijing, China.

Bing Tian (B)

Department of Radiology, Changhai Hospital, Shanghai, China.

Evan Kao (E)

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, USA.

Xinke Liu (X)

Department of Interventional Neuroradiology, Capital Medical University, Beijing Tiantan Hospital, Beijing, China.

Wanling Xuan (W)

Medical College of Georgia at Augusta University, Augusta, USA.

Karen Ordovas (K)

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, USA.

David Saloner (D)

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, USA.
Department of Radiology, Veterans Affairs Medical Center, San Francisco, USA.

Jing Liu (J)

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, USA.

Classifications MeSH