Atg27p localization is clathrin- and Ent3p/5p-dependent.
Journal
microPublication biology
ISSN: 2578-9430
Titre abrégé: MicroPubl Biol
Pays: United States
ID NLM: 101759238
Informations de publication
Date de publication:
29 Mar 2021
29 Mar 2021
Historique:
entrez:
5
4
2021
pubmed:
6
4
2021
medline:
6
4
2021
Statut:
epublish
Résumé
The autophagy-related protein Atg27p has been previously shown to localize to the autophagy-specific pre-autophagosomal structure (PAS) as well as to several organelles, including the late Golgi, the vacuolar membrane, and the endosome. Given that Atg27p localization to the vacuolar membrane in particular has been shown to be dependent on both its C-terminal tyrosine sorting motif and the AP-3 adaptor, and that Atg27p can be found in clathrin-coated vesicles, we set out to determine whether Atg27p localization inside cells is dependent on clathrin or on any of its cargo adaptors. We report that Atg27p localization is clathrin- and Ent3p/5p-dependent.
Identifiants
pubmed: 33817565
doi: 10.17912/micropub.biology.000381
pmc: PMC8008256
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM055796
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007188
Pays : United States
Informations de copyright
Copyright: © 2021 by the authors.
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