Chondroprotective effect of Alpinia oxyphylla extract in experimentally induced cartilage degradation in rabbit articular cartilage explants.
Alpinia oxyphylla
articular cartilage
chondroprotection
inflammation
osteoarthritis
Journal
Journal of food biochemistry
ISSN: 1745-4514
Titre abrégé: J Food Biochem
Pays: United States
ID NLM: 7706045
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
revised:
08
03
2021
received:
14
10
2020
accepted:
15
03
2021
pubmed:
6
4
2021
medline:
10
7
2021
entrez:
5
4
2021
Statut:
ppublish
Résumé
Alpinia oxyphylla is a widely used medicinal herb for diarrhea, gastralgia, tumors, hypertention, and cerebrovascular disorders. Here, we evaluated the chondroprotective effect of A. oxyphylla dried fruit ethanol extract (AOE) against cartilage degradation in rabbit articular cartilage explants. Treatment of interleukin-1α (IL-1α) and plasminogen increased degraded collagen release in culture supernatants, but pretreatment of AOE (50, 100, 200 µg/ml) inhibited the collagen release in dose-dependent manner. To examine the mechanism of action of AOE on chondroprotection, the level of matrix metalloproteinases-3 (MMP-3), matrix metalloproteinases-13 (MMP-13), tissue inhibitor of metalloprotease-1 (TIMP-1), and inflammatory mediators like prostaglandin E
Substances chimiques
Plant Extracts
0
Matrix Metalloproteinases
EC 3.4.24.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13713Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
Al Saedi, A., Feehan, J., Phu, S., & Duque, G. (2019). Current and emerging biomarkers of frailty in the elderly. Clinical Interventions in Aging, 14, 389-398. https://doi.org/10.2147/CIA.S168687
Anderson, A. S., & Loeser, R. F. (2010). Why is OA an age-related disease. Best Practice & Research Clinical Rheumatology, 24(1), 1-18. https://doi.org/10.1016/j.berh.2009.08.006
Bannuru, R. R., Osani, M. C., Vaysbrot, E. E., Arden, N. K., Bennell, K., Bierma-Zeinstra, S., Kraus, V. B., Lohmander, L. S., Abbott, J. H., Bhandari, M., Blanco, F. J., Espinosa, R., Haugen, I. K., Lin, J., Mandl, L. A., Moilanen, E., Nakamura, N., Snyder-Mackler, L., Trojian, T., … McAlindon, T. E. (2019). OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis and Cartilage, 27(11), 1578-1589. https://doi.org/10.1016/j.joca.2019.06.011
Bezerra Rodrigues Dantas, L., Silva, A. L. M., da Silva Júnior, C. P., Alcântara, I. S., Correia de Oliveira, M. R., Oliveira Brito Pereira Bezerra Martins, A., Ribeiro-Filho, J., Coutinho, H. D. M., Rocha Santos Passos, F., Quintans-Junior, L. J., Alencar de Menezes, I. R., Pezzani, R., & Vitalini, S. (2020). Nootkatone inhibits acute and chronic inflammatory responses in mice. Molecules, 25(9), 2181. https://doi.org/10.3390/molecules25092181
Bortoluzzi, A., Furini, F., & Scirè, C. A. (2018). Osteoarthritis and its management-Epidemiology, nutritional aspects and environmental factors. Autoimmunity Reviews, 17(11), 1097-1104. https://doi.org/10.1016/j.autrev.2018.06.002
Brenner, S. S., Klotz, U., Alscher, D. M., Mais, A., Lauer, G., Schweer, H., & Bierbach, U. (2004). Osteoarthritis of the knee-Clinical assessments and inflammatory markers. Osteoarthritis and Cartilage, 12(6), 469-475. https://doi.org/10.1016/j.joca.2004.02.011
Carballo, C. B., Nakagawa, Y., Sekiya, I., & Rodeo, S. A. (2017). Basic science of articular cartilage. Clinics in Sports Medicine, 36(3), 413-425. https://doi.org/10.1016/j.csm.2017.02.001
Chang, S. Y., & Howden, C. W. (2004). Is no NSAID a good NSAID? Approaches to NSAID-associated upper gastrointestinal disease. Current Gastroenterology Reports, 6(6), 447-453. https://doi.org/10.1007/s11894-004-0066-6
Chen, D., Shen, J., Zhao, W., Wang, T., Han, L., Hamilton, J. L., & Im, H. J. (2017). Osteoarthritis: Toward a comprehensive understanding of pathological mechanism. Bone Research, 5(1). https://doi.org/10.1038/boneres.2016.44
Chen, J. J., Huang, J. F., Du, W. X., & Tong, P. J. (2014). Expression and significance of MMP3 in synovium of knee joint at different stage in osteoarthritis patients. Asian Pacific Journal of Tropical Medicine, 7(4), 297-300. https://doi.org/10.1016/S1995-7645(14)60042-0
Cho, Y.-J., Huh, J.-E., Kim, D.-Y., Kim, N.-J., Lee, J.-D., Baek, Y.-H., Cho, E.-M., Yang, H.-R., Choi, D.-Y., & Park, D.-S. (2006). Effect of Betula platyphylla var. japonica on proteoglycan release, type II collagen degradation, and matrix metalloproteinase expression in rabbit articular cartilage explants. Biological and Pharmaceutical Bulletin, 29(7), 1408-1413. https://doi.org/10.1248/bpb.29.1408
Choi, D. J., Choi, S. I., Choi, B. R., Lee, Y. S., Lee, D. Y., & Kim, G. S. (2019). Cartilage protective and anti-analgesic effects of ALM16 on monosodium iodoacetate induced osteoarthritis in rats. BMC Complementary and Alternative Medicine, 19(1), 325. https://doi.org/10.1186/s12906-019-2746-7
d’Abusco, A. S., Calamia, V., Cicione, C., Grigolo, B., Politi, L., & Scandurra, R. (2007). Glucosamine affects intracellular signalling through inhibition of mitogen-activated protein kinase phosphorylation in human chondrocytes. Arthritis Research and Therapy, 9(5), 1-9. https://doi.org/10.1186/ar2307
Goldring, M. B., & Otero, M. (2011). Inflammation in osteoarthritis. Current Opinion in Rheumatology, 23(5), 471-478. https://doi.org/10.1097/BOR.0b013e328349c2b1
Goldring, S. R., & Goldring, M. B. (2016). Changes in the osteochondral unit during osteoarthritis: Structure, function and cartilage bone crosstalk. Nature Reviews Rheumatology, 12(11), 632-644. https://doi.org/10.1038/nrrheum.2016.148
Han, Z., Boyle, D. L., Chang, L., Bennett, B., Karin, M., Yang, L. I., Manning, A. M., & Firestein, G. S. (2001). c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. The Journal of Clinical Investigation, 108(12), 1883. https://doi.org/10.1172/JCI12466C1
Hayakawa, T. (2002). Multiple functions of tissue inhibitors of metalloproteinases (TIMPs): A new aspect involving osteoclastic bone resorption. Journal of Bone and Mineral Metabolism, 20(1), 1-13. https://doi.org/10.1007/s774-002-8440-0
He, Y., Li, Z., Alexander, P. G., Ocasio-Nieves, B. D., Yocum, L., Lin, H., & Tuan, R. S. (2020). Pathogenesis of osteoarthritis: Risk factors, regulatory pathways in chondrocytes, and experimental models. Biology, 9(8), E194. https://doi.org/10.3390/biology9080194
He, Z. H., Ge, W., Yue, G. G. L., Lau, C. B. S., He, M. F., & But, P. P. H. (2010). Anti-angiogenic effects of the fruit of Alpinia oxyphylla. Journal of Ethnopharmacology, 132(2), 443-449. https://doi.org/10.1016/j.jep.2010.08.024
Hunter, D. J., & Bierma-Zeinstra, S. (2019). Osteoarthritis. The Lancet, 393(10182), 1745-1759. https://doi.org/10.1016/S0140-6736(19)30417-9
Is, O., & Guide, S. (2011). Osteoarthritis as a chronic disease. Stg. Jfponline. Com, 21(1), 10-15. https://doi.org/10.1016/j.joca.2012.09.012
Jiang, B., Wang, W.-J., Li, M.-P., Huang, X.-J., Huang, F., Gao, H., Sun, P.-H., He, M.-F., Jiang, Z.-J., Zhang, X.-Q., & Ye, W.-C. (2013). New eudesmane sesquiterpenes from Alpinia oxyphylla and determination of their inhibitory effects on microglia. Bioorganic and Medicinal Chemistry Letters, 23(13), 3879-3883. https://doi.org/10.1016/j.bmcl.2013.04.072
Jo, N. Y., Lee, P. J., & Roh, J. D. (2017). Anti-inflammatory and anti-oxidative effects of Alpiniae Oxyphyllae Fructus hot aqueous extract in lipopolysaccharide (LPS)-stimulated macrophages. The Acupuncture, 34(2), 83-91. https://doi.org/10.13045/acupunct.2017085
Johnson, G. L., & Lapadat, R. (2002). Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science, 298(5600), 1911-1912. https://doi.org/10.1126/science.1072682
Jørgensen, A. E. M., Kjaer, M., & Heinemeier, K. M. (2017). The effect of aging and mechanical loading on the metabolism of articular cartilage. Journal of Rheumatology, 44(4), 410-417. https://doi.org/10.3899/jrheum.160226
Kim, J. H., Ryu, K. H., Jung, K. W., Han, C. K., Kwak, W. J., & Cho, Y. B. (2005). SKI306X suppresses cartilage destruction and inhibits the production of matrix metalloproteinase in rabbit joint cartilage explant culture. Journal of Pharmacological Sciences, 98(3), 298-306. https://doi.org/10.1254/jphs.FPJ04058X
Kongdang, P., Chokchaitaweesuk, C., & Tangyuenyong, S. (2019). IL-17A promoted cartilage degradation and suppressed genes associated with cartilage matrix. Molecules, 24(20), 3682. https://doi.org/10.3390/molecules24203682
Lee, Y. M., Son, E., Kim, S. H., & Kim, D. S. (2019). Effect of Alpinia oxyphylla extract in vitro and in a monosodium iodoacetate-induced osteoarthritis rat model. Phytomedicine, 65, 153095. https://doi.org/10.1016/j.phymed.2019.153095
Li, H., Wang, D., Yuan, Y., & Min, J. (2017). New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis. Arthritis Research and Therapy, 19(1), 1-12. https://doi.org/10.1186/s13075-017-1454-2
Liacini, A., Sylvester, J., Li, W. Q., Huang, W., Dehnade, F., Ahmad, M., & Zafarullah, M. (2003). Induction of matrix metalloproteinase-13 gene expression by TNF-α is mediated by MAP kinases, AP-1, and NF-κB transcription factors in articular chondrocytes. Experimental Cell Research, 288(1), 208-217. https://doi.org/10.1016/S0014-4827(03)00180-0
Loeser, R. F. (2006). Molecular mechanisms of cartilage destruction: Mechanics, inflammatory mediators, and aging collide. Arthritis & Rheumatism, 54(5), 1357-1360. https://doi.org/10.1038/jid.2014.371
Martel-Pelletier, J., Barr, A. J., Cicuttini, F. M., Conaghan, P. G., Cooper, C., Goldring, M. B., Goldring, S. R., Jones, G., Teichtahl, A. J., & Pelletier, J.-P. (2016). Osteoarthritis. Nature Reviews Disease Primers, 2. https://doi.org/10.1038/nrdp.2016.72
Martel-Pelletier, J., Welsch, D. J., & Pelletier, J. P. (2001). Metalloproteases and inhibitors in arthritic diseases. Best Practice and Research: Clinical Rheumatology, 15(5), 805-829. https://doi.org/10.1053/berh.2001.0195
Masuko-Hongo, K., Berenbaum, F., Humbert, L., Salvat, C., Goldring, M. B., & Thirion, S. (2004). Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: Critical roles of the ERK-1/2 and p38 signaling pathways. Arthritis and Rheumatism, 50(9), 2829-2838. https://doi.org/10.1002/art.20437
Mehana, E. S. E., Khafaga, A. F., & El-Blehi, S. S. (2019). The role of matrix metalloproteinases in osteoarthritis pathogenesis: An updated review. Life Sciences, 234, 116786. https://doi.org/10.1016/j.lfs.2019.116786
Mengshol, J. A., Vincenti, M. P., Coon, C. I., Barchowsky, A., & Brinckerhoff, C. E. (2000). Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor κB: Differential regulation of collagenase 1 and collagenase 3. Arthritis and Rheumatism, 43(4), 801-811. https://doi.org/10.1002/1529-0131(200004)43:4<801:AID-ANR10>3.0.CO;2-4
Moon, P. D., Jeong, H. S., Chun, C. S., & Kim, H. M. (2011). Baekjeolyusin-tang and its active component berberine block the release of collagen and proteoglycan from IL-1β-stimulated rabbit cartilage and down-regulate matrix metalloproteinases in rabbit chondrocytes. Phytotherapy Research, 25(6), 844-850. https://doi.org/10.1002/ptr.3353
Murphy, G. (2011). Tissue inhibitors of metalloproteinases. Genome Biology, 12(11), 233. https://doi.org/10.1186/gb-2011-12-11-233
Pathak, N. N., Lingaraju, M. C., Balaganur, V., Kant, V., More, A. S., Kumar, D., Kumar, D., & Tandan, S. K. (2015). Anti-inflammatory and chondroprotective effects of atorvastatin in a cartilage explant model of osteoarthritis. Inflammation Research, 64(3-4), 161-169. https://doi.org/10.1007/s00011-014-0794-5
Pelletier, J. P., Fernandes, J. C., Brunet, J., Moldovan, F., Schrier, D., Flory, C., & Martel-Pelletier, J. (2003). In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes. Arthritis and Rheumatism, 48(6), 1582-1593. https://doi.org/10.1002/art.11014
Qing, Z. J., Yong, W., Hui, L. Y., Yong, L. W., Long, L. H., Ao, D. J., & Xia, P. L. (2012). Two new natural products from the fruits of Alpinia oxyphylla with inhibitory effects on nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophage cells. Archives of Pharmacal Research, 35(12), 2143-2146. https://doi.org/10.1007/s12272-012-1211-7
Saito, S., Katoh, M., Masumoto, M., Matsumoto, S. I., & Masuho, Y. (1997). Collagen degradation induced by the combination of IL-la and plasminogen in rabbit articular cartilage explant culture. Journal of Biochemistry, 122(1), 49-54. https://doi.org/10.1248/bpb.22.727
Saito, S., Katoh, M., Masumoto, M., Matsumoto, S. I., & Masuho, Y. (1999). Dexamethasone inhibits collagen degradation induced by the combination of interleukin-1 and plasminogen in cartilage explant culture. Biological and Pharmaceutical Bulletin, 22(7), 727-730. http://www.mendeley.com/research/geology-volcanic-history-eruptive-style-yakedake-volcano-group-central-japan/ https://doi.org/10.1248/bpb.22.727
Sato, T., Konomi, K., Yamasaki, S., Aratani, S., Tsuchimochi, K., Yokouchi, M., Masuko-Hongo, K., Yagishita, N., Nakamura, H., Komiya, S., Beppu, M., Aoki, H., Nishioka, K., & Nakajima, T. (2006). Comparative analysis of gene expression profiles in intact and damaged regions of human osteoarthritic cartilage. Arthritis and Rheumatism, 54(3), 808-817. https://doi.org/10.1002/art.21638
Stanton, L. A., Sabari, S., Sampaio, A. V., Underhill, T. M., & Beier, F. (2004). p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation. Biochemical Journal, 378(1), 53-62. https://doi.org/10.1042/BJ20030874
Sun, S., Bay-Jensen, A.-C., Karsdal, M. A., Siebuhr, A. S., Zheng, Q., Maksymowych, W. P., Christiansen, T. G., & Henriksen, K. (2014). The active form of MMP-3 is a marker of synovial inflammation and cartilage turnover in inflammatory joint diseases. BMC Musculoskeletal Disorders, 15(1), 1-8. https://doi.org/10.1186/1471-2474-15-93
Tchetverikov, I., Ronday, H. K., Van El, B., Kiers, G. H., Verzijl, N., TeKoppele, J. M., & Hanemaaijer, R. (2004). MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 63(7), 881-883. https://doi.org/10.1136/ard.2003.013243
Tetlow, L. C., Adlam, D. J., & Woolley, D. E. (2001). Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage; Associations with degenerative changes. Arthritis and Rheumatism, 44(3), 585-594. https://doi.org/10.1002/1529-0131(200103)44:3<585:AID-ANR107>3.0.CO;2-C
Thalhamer, T., McGrath, M. A., & Harnett, M. M. (2008). MAPKs and their relevance to arthritis and inflammation. Rheumatology, 47(4), 409-414. https://doi.org/10.1093/rheumatology/kem297
Tsoyi, K., Jang, H. J., Lee, Y. S., Kim, Y. M., Kim, H. J., Seo, H. G., Lee, J. H., Kwak, J. H., Lee, D.-U., & Chang, K. C. (2011). (+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction. Journal of Ethnopharmacology, 137(3), 1311-1317. https://doi.org/10.1016/j.jep.2011.07.062
Vincent, T. L. (2019). Il-1 in osteoarthritis: Time for a critical review of the literature. F1000Research, 8, 1-8. https://doi.org/10.12688/f1000research.18831.1
Wu, J. P., Kirk, T. B., & Zheng, M. H. (2008). Study of the collagen structure in the superficial zone and physiological state of articular cartilage using a 3D confocal imaging technique. Journal of Orthopaedic Surgery and Research, 3(1), 1-11. https://doi.org/10.1186/1749-799X-3-29
Xia, B., Chen, D. I., Zhang, J., Hu, S., Jin, H., & Tong, P. (2014). Osteoarthritis pathogenesis: A review of molecular mechanisms. Calcified Tissue International, 95(6), 495-505. https://doi.org/10.1007/s00223-014-9917-9
Yamahara, J., Li, Y. H., & Tamai, Y. (1990). Anti-ulcer effect in rats of bitter cardamon constituents. Chemical Pharmaceutical Bulletin, 38(11), 3053-3054. https://doi.org/10.1248/cpb.38.3053
Yu, S. H., Kim, H. J., Jeon, S. Y., Kim, M. R., Lee, B. S., Lee, J. J., Kim, D.-S., & Lee, Y. C. (2020). Anti-inflammatory and anti-nociceptive activities of Alpinia oxyphylla Miquel extracts in animal models. Journal of Ethnopharmacology, 260, 112985. https://doi.org/10.1016/j.jep.2020.112985
Yu, X., An, L., Wang, Y., Zhao, H., & Gao, C. (2003). Neuroprotective effect of Alpinia oxyphylla Miq. fruits against glutamate-induced apoptosis in cortical neurons. Toxicology Letters, 144(2), 205-212. https://doi.org/10.1016/S0378-4274(03)00219-4
Zhao, X., Wei, J., Shu, X., Kong, W., & Yang, M. (2016). Multi-elements determination in medical and edible Alpinia oxyphylla and Morinda officinalis and their decoctions by ICP-MS. Chemosphere, 164, 430-435. https://doi.org/10.1016/j.chemosphere.2016.08.122