Neuroblastoma.
MIBG
autologous stem cell rescue
chemotherapy
immunotherapy
neuroblastoma
radiation therapy
surgery
Journal
Pediatric blood & cancer
ISSN: 1545-5017
Titre abrégé: Pediatr Blood Cancer
Pays: United States
ID NLM: 101186624
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
revised:
15
05
2020
received:
28
01
2020
accepted:
18
05
2020
entrez:
5
4
2021
pubmed:
6
4
2021
medline:
25
9
2021
Statut:
ppublish
Résumé
The survival of patients with high-risk neuroblastoma has improved significantly with the use of intensive multimodality treatment regimens, including chemotherapy, surgery, radiation therapy, myeloablative chemotherapy followed by stem cell rescue, and immunotherapy. This report summarizes the current treatment strategies used in the COG and SIOP for children with neuroblastoma. The improved global collaboration and the adoption of a uniform International Neuroblastoma Risk Group Staging System will help facilitate comparison of homogeneous pretreatment cohorts across clinical trials. Future research strategies regarding the indications for and dosages of radiation therapy to the primary and metastatic sites, and the integration of meta-iodobenzyl guanidine therapy into the multimodal treatment program, are discussed.
Identifiants
pubmed: 33818884
doi: 10.1002/pbc.28473
pmc: PMC8785544
mid: NIHMS1763547
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e28473Subventions
Organisme : NCI NIH HHS
ID : P30 CA021765
Pays : United States
Informations de copyright
© 2021 Wiley Periodicals LLC.
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