Caffeine - treat or trigger? Disparate behavioral and long-term dopaminergic changes in control and schizophrenia-like Wisket rats.

Animals Brain Caffeine / pharmacology Dopamine Humans Prefrontal Cortex Rats Schizophrenia / chemically induced
Behavior Caffeine Cognition Dopamine D(2) receptor Rat Schizophrenia

Journal

Physiology & behavior
ISSN: 1873-507X
Titre abrégé: Physiol Behav
Pays: United States
ID NLM: 0151504

Informations de publication

Date de publication:
01 07 2021
Historique:
received: 15 01 2021
revised: 12 03 2021
accepted: 26 03 2021
pubmed: 6 4 2021
medline: 29 6 2021
entrez: 5 4 2021
Statut: ppublish

Résumé

The influence of caffeine on behavioral functions in both healthy and schizophrenic subjects is controversial. Here we aimed to reveal the effects of repeated caffeine pre- and post-training treatments on motor and exploratory activities and cognitive functions in a reward-based test (Ambitus) along with a brain region-specific dopamine D

Identifiants

DOI: 10.1016/j.physbeh.2021.113410 PMID: 33819453
pubmed: 33819453
pii: S0031-9384(21)00102-5
doi: 10.1016/j.physbeh.2021.113410
pii:
doi:

Substances chimiques

Caffeine 3G6A5W338E
Dopamine VTD58H1Z2X

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

113410

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

G Horvath (G)

Department of Physiology, Faculty of Medicine, University of Szeged, H-6720 Szeged, Hungary. Electronic address: horvath.gyongyi@med.u-szeged.hu.

G Adam (G)

Department of Pulmonology, Faculty of Medicine, University of Szeged, H-6772 Szeged, Hungary.

G Tuboly (G)

Department of Neurology, Faculty of Medicine, University of Szeged, H-6725 Szeged, Hungary.

G Kekesi (G)

Department of Physiology, Faculty of Medicine, University of Szeged, H-6720 Szeged, Hungary.

A Büki (A)

Department of Physiology, Faculty of Medicine, University of Szeged, H-6720 Szeged, Hungary.

E Ducza (E)

Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, H-6720 Szeged, Hungary.

E Szűcs (E)

Institute of Biochemistry, Biological Research Center, Hungarian Academy of Sciences, H-6726 Szeged, Hungary; Doctoral School of Theoretical Medicine, Faculty of Medicine, University of Szeged, H-6720 Szeged, Hungary.

S Benyhe (S)

Institute of Biochemistry, Biological Research Center, Hungarian Academy of Sciences, H-6726 Szeged, Hungary.

G Benedek (G)

Department of Physiology, Faculty of Medicine, University of Szeged, H-6720 Szeged, Hungary.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Caffeine - treat or trigger? Disparate...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Caffeine - treat or trigger? Disparate...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Purines › Purinones › Xanthines › Caféine › Caffeine - treat or trigger? Disparate...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Catéchols › Catécholamines › Dopamine › Caffeine - treat or trigger? Disparate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Caffeine - treat or trigger? Disparate...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Lobe frontal › Cortex préfrontal › Caffeine - treat or trigger? Disparate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Caffeine - treat or trigger? Disparate...
questionsmedicales.fr › Troubles mentaux › Schizophrénie et troubles avec traits psychotiques › Schizophrénie › Caffeine - treat or trigger? Disparate...