The Impact of Physical Exercise on the Hippocampus in Physiological Condition and Ageing-Related Decline: Current Evidence from Animal and Human Studies.
Physical exercise
aging
cognitive decline
cognitive impairment
hippocampus
neurogenesis
neurotrophic factors.
Journal
Current pharmaceutical biotechnology
ISSN: 1873-4316
Titre abrégé: Curr Pharm Biotechnol
Pays: Netherlands
ID NLM: 100960530
Informations de publication
Date de publication:
2022
2022
Historique:
received:
19
11
2020
revised:
19
01
2021
accepted:
14
02
2021
pubmed:
7
4
2021
medline:
20
1
2022
entrez:
6
4
2021
Statut:
ppublish
Résumé
Physical exercise (PE), notoriously, promotes a state of general well-being, throughout the entire human lifespan. Moreover, maintaining an adequate and regular PE habit results in a powerful preventive factor towards many diseases and may also help in managing existing pathological conditions. PE induces structural and functional changes in various parts of the body, determining biological and psychological benefits. Additionally, in the elderly, PE might represent a remarkable tool reducing cognitive impairments related to the normal aging processes and it has also been found to have an impact on neurodegenerative diseases such as Alzheimer's disease. The present review aims to provide an overview of PE effects on the hippocampus, since it is one of the brain regions most susceptible to aging and, therefore, involved in diseases characterized by cognitive impairment.
Identifiants
pubmed: 33820516
pii: CPB-EPUB-115197
doi: 10.2174/1389201022666210405142611
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
180-189Subventions
Organisme : Department of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania
ID : (PIACERI FOUND - NATURE-OA - 2020 -2022)
Informations de copyright
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.