Toward Raman Subcellular Imaging of Endothelial Dysfunction.
Journal
Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531
Informations de publication
Date de publication:
22 04 2021
22 04 2021
Historique:
pubmed:
7
4
2021
medline:
17
6
2021
entrez:
6
4
2021
Statut:
ppublish
Résumé
Multiple diseases are at some point associated with altered endothelial function, and endothelial dysfunction (ED) contributes to their pathophysiology. Biochemical changes of the dysfunctional endothelium are linked to various cellular organelles, including the mitochondria, endoplasmic reticulum, and nucleus, so organelle-specific insight is needed for better understanding of endothelial pathobiology. Raman imaging, which combines chemical specificity with microscopic resolution, has proved to be useful in detecting biochemical changes in ED at the cellular level. However, the detection of spectroscopic markers associated with specific cell organelles, while desirable, cannot easily be achieved by Raman imaging without labeling. This critical review summarizes the current advances in Raman-based analysis of ED, with a focus on a new approach involving molecular Raman reporters that could facilitate the study of biochemical changes in cellular organelles. Finally, imaging techniques based on both conventional spontaneous Raman scattering and the emerging technique of stimulated Raman scattering are discussed.
Identifiants
pubmed: 33821652
doi: 10.1021/acs.jmedchem.1c00051
pmc: PMC8154563
doi:
Substances chimiques
Molecular Probes
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
4396-4409Références
J Clin Invest. 2001 Nov;108(9):1341-8
pubmed: 11696579
Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13394-13399
pubmed: 29196526
Physiol Behav. 2017 Jul 1;176:139-148
pubmed: 28363838
J Phys Chem Lett. 2011 May 9;2(11):1248-1253
pubmed: 21731798
PLoS One. 2014 Aug 28;9(8):e106065
pubmed: 25166908
Circ Res. 2008 Feb 29;102(4):488-96
pubmed: 18096818
Nat Biomed Eng. 2019 May;3(5):402-413
pubmed: 31036888
Circ Res. 2016 Jun 10;118(12):1960-91
pubmed: 27126807
Nature. 2017 Apr 27;544(7651):465-470
pubmed: 28424513
ACS Cent Sci. 2020 Apr 22;6(4):478-486
pubmed: 32341997
Nanomedicine. 2019 Feb;16:97-105
pubmed: 30550804
Exp Cell Res. 2017 Sep 1;358(1):31-38
pubmed: 28602626
J Am Chem Soc. 2012 Dec 26;134(51):20681-9
pubmed: 23198907
Lipids Health Dis. 2017 Jan 17;16(1):12
pubmed: 28095860
Chem Rev. 2017 Aug 9;117(15):10043-10120
pubmed: 28654243
J Biomed Opt. 2016 Jun;21(6):61003
pubmed: 26719944
Analyst. 2019 Nov 4;144(22):6561-6569
pubmed: 31576836
Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9821-5
pubmed: 26207979
Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):28-32
pubmed: 22184220
Angew Chem Int Ed Engl. 2014 May 26;53(22):5596-9
pubmed: 24737659
Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11226-31
pubmed: 23798434
Circ Res. 2013 Apr 12;112(8):1171-88
pubmed: 23580773
Int J Mol Sci. 2019 Apr 03;20(7):
pubmed: 30987118
Analyst. 2020 Aug 7;145(15):5289-5298
pubmed: 32672252
Clin Exp Pharmacol Physiol. 2016 Nov;43(11):1021-1028
pubmed: 27558982
J Biophotonics. 2017 Sep;10(9):1217-1226
pubmed: 28164480
Analyst. 2014 Mar 7;139(5):1155-61
pubmed: 24427772
Analyst. 2018 Feb 12;143(4):970-980
pubmed: 29372724
Sci Rep. 2016 Jun 24;6:28483
pubmed: 27339882
J Clin Hypertens (Greenwich). 2006 Dec;8(12 Suppl 4):17-29
pubmed: 17170603
PLoS One. 2012;7(1):e30387
pubmed: 22253932
Chem Commun (Camb). 2018 Jan 7;54(2):152-155
pubmed: 29218356
J Am Chem Soc. 2014 Jun 4;136(22):8027-33
pubmed: 24849912
Pharmacol Rep. 2015 Aug;67(4):vi-ix
pubmed: 26321287
Vasc Health Risk Manag. 2007;3(6):853-76
pubmed: 18200806
Analyst. 2019 Apr 8;144(8):2531-2540
pubmed: 30839952
Anal Chem. 2021 Feb 2;93(4):2377-2384
pubmed: 33443405
Nat Methods. 2018 Mar;15(3):194-200
pubmed: 29334378
Pharmacol Rep. 2015 Aug;67(4):736-43
pubmed: 26321275
Biomaterials. 2015 Jun;53:25-31
pubmed: 25890703
Antioxid Redox Signal. 2014 Jan 10;20(2):281-94
pubmed: 24053613
Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):E194-203
pubmed: 25550518
Circulation. 2002 Aug 6;106(6):640-2
pubmed: 12163419
Sci Transl Med. 2015 Oct 14;7(309):309ra163
pubmed: 26468325
Analyst. 2016 Feb 21;141(4):1390-7
pubmed: 26765153
Cardiovasc Res. 2015 Jul 15;107(2):295-306
pubmed: 26038299
Bioorg Med Chem Lett. 2015 Feb 1;25(3):664-7
pubmed: 25522818
Chem Sci. 2017 Aug 1;8(8):5606-5615
pubmed: 30155229
Nat Commun. 2020 Jan 3;11(1):81
pubmed: 31900403
Nat Commun. 2018 Aug 6;9(1):2995
pubmed: 30082908
Nat Methods. 2014 Apr;11(4):410-2
pubmed: 24584195
Chem Commun (Camb). 2019 Aug 1;55(63):9379-9382
pubmed: 31317975
Anal Chem. 2020 Jan 7;92(1):740-748
pubmed: 31750649
Analyst. 2015 Apr 7;140(7):2178-84
pubmed: 25502217
J Med Chem. 2020 Mar 12;63(5):2028-2034
pubmed: 31829628
Analyst. 2015 Apr 7;140(7):2185-9
pubmed: 25664353
Arterioscler Thromb Vasc Biol. 2007 Aug;27(8):1687-93
pubmed: 17556654
ACS Chem Biol. 2015 Mar 20;10(3):901-8
pubmed: 25560305
Anal Chem. 2019 Feb 5;91(3):2279-2287
pubmed: 30589537
Anal Chem. 2020 Oct 6;92(19):13182-13191
pubmed: 32907318
Photosynth Res. 2009 Aug-Sep;101(2-3):147-55
pubmed: 19568956
Spectrochim Acta A Mol Biomol Spectrosc. 2018 May 15;197:30-36
pubmed: 29525355
Mol Ther. 2013 Dec;21(12):2195-204
pubmed: 23959073
Analyst. 2014 May 21;139(10):2312-7
pubmed: 24555181
Analyst. 2016 Jun 21;141(12):3590-600
pubmed: 27072718
Sci Rep. 2019 Dec 31;9(1):20392
pubmed: 31892723
Nat Med. 2003 Mar;9(3):294-9
pubmed: 12592403
Nat Rev Immunol. 2007 Oct;7(10):803-15
pubmed: 17893694
Biochim Biophys Acta Mol Cell Res. 2020 Jun;1867(6):118681
pubmed: 32084444
Hypertension. 2004 Nov;44(5):739-45
pubmed: 15381675
Cell Death Differ. 2019 Mar;26(4):665-679
pubmed: 30692642
Biochim Biophys Acta Mol Cell Res. 2021 Feb;1868(2):118911
pubmed: 33227312
Pharmacol Rep. 2015 Aug;67(4):744-50
pubmed: 26321276
Arterioscler Thromb Vasc Biol. 2020 Jul;40(7):e193-e202
pubmed: 32404005
Sci Rep. 2015 Jan 22;5:7930
pubmed: 25608867
Chem Commun (Camb). 2017 Jun 6;53(46):6187-6190
pubmed: 28474031
Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H992-H1002
pubmed: 20061541
Free Radic Biol Med. 2020 Sep;157:15-37
pubmed: 32131026
Anal Chem. 2017 Apr 4;89(7):4108-4115
pubmed: 28282113
Am J Physiol Heart Circ Physiol. 2017 Mar 1;312(3):H355-H367
pubmed: 27923788
Arterioscler Thromb Vasc Biol. 2020 Feb;40(2):301-308
pubmed: 31875699
Redox Biol. 2017 Oct;13:581-587
pubmed: 28783588
J Phys Chem Lett. 2018 Aug 2;9(15):4294-4301
pubmed: 30001137
J Am Chem Soc. 2020 Dec 9;142(49):20701-20707
pubmed: 33225696
Biomed Opt Express. 2019 Sep 30;10(10):5378-5384
pubmed: 31646052
J Phys Chem Lett. 2018 Aug 16;9(16):4679-4685
pubmed: 30067370
Pharmacol Rep. 2015 Aug;67(4):811-7
pubmed: 26321285
Heart. 2010 Dec;96(23):1872-7
pubmed: 20837663
Front Pharmacol. 2017 Apr 10;8:183
pubmed: 28443021
Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7250-7254
pubmed: 29645336
Cell Mol Life Sci. 2021 Apr;78(7):3477-3484
pubmed: 33289850
Antioxid Redox Signal. 2014 Mar 1;20(7):1126-67
pubmed: 23991888
Biochem Biophys Res Commun. 2011 Jun 17;409(4):711-6
pubmed: 21621514
J Pharmacol Exp Ther. 2016 Feb;356(2):514-24
pubmed: 26631491
Pflugers Arch. 2012 Jul;464(1):63-76
pubmed: 22382745
Chem Sci. 2019 May 24;10(24):6035-6071
pubmed: 31360411
Int J Biol Sci. 2013 Nov 09;9(10):1057-69
pubmed: 24250251
Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2415-20
pubmed: 18272492
Sci Rep. 2018 Feb 26;8(1):3606
pubmed: 29483581
Circ Res. 2015 Jan 30;116(3):480-8
pubmed: 25634971
Nat Chem. 2014 Jul;6(7):614-22
pubmed: 24950332
Food Funct. 2017 Jan 25;8(1):39-63
pubmed: 27924978
Angew Chem Int Ed Engl. 2014 Jun 2;53(23):5827-31
pubmed: 24753329
J Am Chem Soc. 2011 Apr 27;133(16):6102-5
pubmed: 21443184
Analyst. 2017 Oct 23;142(21):4018-4029
pubmed: 28875184
Curr Opin Chem Biol. 2013 Aug;17(4):708-15
pubmed: 23773582
J Clin Invest. 2003 Oct;112(7):1049-57
pubmed: 14523042