Angio-Based Fractional Flow Reserve, Functional Pattern of Coronary Artery Disease, and Prediction of Percutaneous Coronary Intervention Result: a Proof-of-Concept Study.
Angio-based fractional flow reserve
Functional pattern of coronary artery disease
Percutaneous coronary intervention
Pressure pullback gradient
Quantitative flow ratio
Journal
Cardiovascular drugs and therapy
ISSN: 1573-7241
Titre abrégé: Cardiovasc Drugs Ther
Pays: United States
ID NLM: 8712220
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
accepted:
21
02
2021
pubmed:
9
4
2021
medline:
14
7
2022
entrez:
8
4
2021
Statut:
ppublish
Résumé
Wire-based coronary physiology pullback performed before percutaneous coronary intervention (PCI) discriminates coronary artery disease (CAD) distribution and extent, and is able to predict functional PCI result. No research investigated if quantitative flow ratio (QFR)-based physiology assessment is able to provide similar information. In 111 patients (120 vessels) treated with PCI, QFR was measured both before and after PCI. Pre-PCI QFR trace was used to discriminate functional patterns of CAD (focal, serial lesions, diffuse disease, combination). Functional CAD patterns were identified analyzing changes in the QFR virtual pullback trace (qualitative method) or after computation of the QFR virtual pullback index (QVP By qualitative method, 51 (43%), 20 (17%), 15 (12%), and 34 (28%) vessels were classified as focal, serial focal lesions, diffuse disease, and combination, respectively. QVP Our results suggest that functional patterns of CAD based on pre-PCI QFR trace can predict the functional outcome after PCI. ClinicalTrials.gov , number NCT02811796. Date of registration: June 23, 2016.
Identifiants
pubmed: 33830399
doi: 10.1007/s10557-021-07162-6
pii: 10.1007/s10557-021-07162-6
pmc: PMC9270302
doi:
Banques de données
ClinicalTrials.gov
['NCT02811796']
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
645-653Informations de copyright
© 2021. The Author(s).
Références
Circ Cardiovasc Interv. 2018 Feb;11(2):e006023
pubmed: 29449325
Circ Cardiovasc Interv. 2019 Feb;12(2):e007030
pubmed: 30732469
JACC Cardiovasc Interv. 2020 Nov 23;13(22):2670-2684
pubmed: 33069650
JACC Cardiovasc Imaging. 2021 Sep;14(9):1846-1855
pubmed: 33248968
JACC Cardiovasc Interv. 2018 Aug 13;11(15):1482-1491
pubmed: 29803695
Catheter Cardiovasc Interv. 2021 Mar;97(4):614-622
pubmed: 32845067
J Am Coll Cardiol. 2019 Oct 8;74(14):1772-1784
pubmed: 31582137
JACC Cardiovasc Interv. 2020 Nov 23;13(22):2688-2698
pubmed: 33129819
JACC Cardiovasc Interv. 2019 Oct 28;12(20):2079-2088
pubmed: 31563688
J Am Heart Assoc. 2018 Jul 6;7(14):
pubmed: 29980523