Matrix-associated autologous chondrocyte implantation with autologous bone grafting of osteochondral lesions of the talus in adolescents: patient-reported outcomes with a median follow-up of 6 years.
Adolescent
Age Factors
Bone Transplantation
/ methods
Cartilage, Articular
/ surgery
Chondrocytes
/ transplantation
Female
Follow-Up Studies
Humans
Male
Orthopedic Procedures
/ methods
Osteoarthritis
/ surgery
Osteochondritis
/ surgery
Talus
/ surgery
Time Factors
Transplantation, Autologous
Treatment Outcome
Young Adult
Adolescents
Ankle
Autologous bone grafting
Autologous chondrocyte implantation
Children
Matrix-associated autologous chondrocyte implantation
Osteoarthritis
Osteochondral lesion
Patient-reported outcome measures
Talus
Journal
Journal of orthopaedic surgery and research
ISSN: 1749-799X
Titre abrégé: J Orthop Surg Res
Pays: England
ID NLM: 101265112
Informations de publication
Date de publication:
08 Apr 2021
08 Apr 2021
Historique:
received:
06
02
2021
accepted:
24
03
2021
entrez:
9
4
2021
pubmed:
10
4
2021
medline:
6
10
2021
Statut:
epublish
Résumé
This study presents patient-reported outcome measures after combined matrix-associated autologous chondrocyte implantation and autologous bone grafting in high-stage osteochondral lesions of the talus in adolescents. A total of 12 adolescent patients (13 ankles) received matrix-associated autologous chondrocyte implantation and autologous bone grafting for a solitary osteochondral lesion of the talus at a single centre. The Foot and Ankle Outcome Score and Foot and Ankle Ability Measure were defined as outcome measures (median follow-up 80 months [range 22-107 months]). Pre- and postoperative ankle radiographs were evaluated according to the van Dijk ankle osteoarthritis scale. The study population consisted of four male and nine female cases (mean age at the time of surgery, 17.7 ± 2.1 years). Eight lesions were classified as traumatic and five as idiopathic. Twelve lesions were located medial vs one lateral in the coronal plane and all central in the sagittal plane. The median lesion size and depth were 1.3 cm
Sections du résumé
BACKGROUND
BACKGROUND
This study presents patient-reported outcome measures after combined matrix-associated autologous chondrocyte implantation and autologous bone grafting in high-stage osteochondral lesions of the talus in adolescents.
METHODS
METHODS
A total of 12 adolescent patients (13 ankles) received matrix-associated autologous chondrocyte implantation and autologous bone grafting for a solitary osteochondral lesion of the talus at a single centre. The Foot and Ankle Outcome Score and Foot and Ankle Ability Measure were defined as outcome measures (median follow-up 80 months [range 22-107 months]). Pre- and postoperative ankle radiographs were evaluated according to the van Dijk ankle osteoarthritis scale.
RESULTS
RESULTS
The study population consisted of four male and nine female cases (mean age at the time of surgery, 17.7 ± 2.1 years). Eight lesions were classified as traumatic and five as idiopathic. Twelve lesions were located medial vs one lateral in the coronal plane and all central in the sagittal plane. The median lesion size and depth were 1.3 cm
Identifiants
pubmed: 33832525
doi: 10.1186/s13018-021-02384-8
pii: 10.1186/s13018-021-02384-8
pmc: PMC8028759
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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