A Novel Grape-Derived Prebiotic Selectively Enhances Abundance and Metabolic Activity of Butyrate-Producing Bacteria in Faecal Samples.

butyrate gut health gut microbiota inflammatory bowel disease irritable bowel syndrome prebiotic

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2021
Historique:
received: 10 12 2020
accepted: 22 02 2021
entrez: 9 4 2021
pubmed: 10 4 2021
medline: 10 4 2021
Statut: epublish

Résumé

Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) patients have different faecal microbiota profiles compared to healthy controls. Prebiotics intake influences intestinal microbiota composition which in turn influence the growth of short-chain fatty acids (SCFA) producing bacteria. This study aimed to evaluate the capacity of Previpect, a new prebiotic obtained from grapes fibre, to balance the dysbiosis found in patients with intestinal disorders. This was achieved through the analysis of specific bacterial markers and SCFA production using an

Identifiants

pubmed: 33833742
doi: 10.3389/fmicb.2021.639948
pmc: PMC8021714
doi:

Types de publication

Journal Article

Langues

eng

Pagination

639948

Informations de copyright

Copyright © 2021 Oliver, Ramió-Pujol, Amoedo, Malagón, Serrano, Bahí, Lluansí, Torrealba, Busquets, Pardo, Serra-Pagès, Aldeguer and Garcia-Gil.

Déclaration de conflit d'intérêts

LO, SR-P, JA, MM, MS, MS-P, and XA were employed by company GoodGut SL, Girona, Spain. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Lia Oliver (L)

GoodGut SL, Girona, Spain.

Sara Ramió-Pujol (S)

GoodGut SL, Girona, Spain.

Joan Amoedo (J)

GoodGut SL, Girona, Spain.

Marta Malagón (M)

GoodGut SL, Girona, Spain.

Marta Serrano (M)

GoodGut SL, Girona, Spain.

Anna Bahí (A)

Institut d'Investigació Biomèdica de Girona-IDIBGI, Salt, Spain.

Aleix Lluansí (A)

Institut d'Investigació Biomèdica de Girona-IDIBGI, Salt, Spain.

Leyanira Torrealba (L)

Hospital Universitari de Girona Dr. Josep Trueta, Girona, Spain.

David Busquets (D)

Hospital Universitari de Girona Dr. Josep Trueta, Girona, Spain.

Laura Pardo (L)

Hospital Universitari de Girona Dr. Josep Trueta, Girona, Spain.

Mariona Serra-Pagès (M)

GoodGut SL, Girona, Spain.

Xavier Aldeguer (X)

GoodGut SL, Girona, Spain.
Institut d'Investigació Biomèdica de Girona-IDIBGI, Salt, Spain.
Hospital Universitari de Girona Dr. Josep Trueta, Girona, Spain.

Jesús Garcia-Gil (J)

Department of Biology, University of Girona, Girona, Spain.

Classifications MeSH