Long-Term Cognitive Outcomes and Sleep in Adults After Extracorporeal Life Support.
actigraphy
cognition
critical care outcomes
extracorporeal membrane oxygenation
Journal
Critical care explorations
ISSN: 2639-8028
Titre abrégé: Crit Care Explor
Pays: United States
ID NLM: 101746347
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
entrez:
9
4
2021
pubmed:
10
4
2021
medline:
10
4
2021
Statut:
epublish
Résumé
To assess differences in cognitive outcomes and sleep in adult survivors of critical illness, managed with venovenous extracorporeal membrane oxygenation as compared to conventional mechanical ventilation only. Retrospective cohort study linked with data from the COGnitive outcomes and WELLness study. A multisite study from five adult medical/surgical ICUs in Toronto. Thirty-three ICU survivors including adult patients who received venovenous extracorporeal membrane oxygenation ( None. Baseline demographics and admission diagnoses were collected at enrollment. Cognitive outcome was evaluated using the Repeatable Battery for the Assessment of Neuropsychologic Status (global cognitive function) and Trail Making Test B (executive function), and sleep variables were estimated using actigraphy. Assessments occurred at 7 days post ICU discharge and again at 6- and 12-month follow-up. No statistically significant difference was seen between patients treated with or without venovenous extracorporeal membrane oxygenation in the mean daily Riker Sedation Agitation Score; however, patients in the venovenous extracorporeal membrane oxygenation group received greater amounts of fentanyl over their ICU stay as compared to patients receiving conventional mechanical ventilation only ( In this small retrospective case series, no significant differences were found in sleep or cognitive outcomes between extracorporeal life support and non-extracorporeal life support survivors. Further, in this hypothesis-generating study, differences in administered sedative doses during the ICU stay seen between the two groups did not impact 6- or 12-month cognitive performance or actigraphy-estimated sleep time.
Identifiants
pubmed: 33834171
doi: 10.1097/CCE.0000000000000390
pmc: PMC8021370
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e0390Informations de copyright
Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.
Déclaration de conflit d'intérêts
The authors have disclosed that they do not have any potential conflicts of interest.
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