Ambient carbon monoxide and daily mortality: a global time-series study in 337 cities.

Air Pollutants / analysis Air Pollution / adverse effects Carbon Monoxide Cardiovascular Diseases Cities Humans

Journal

The Lancet. Planetary health
ISSN: 2542-5196
Titre abrégé: Lancet Planet Health
Pays: Netherlands
ID NLM: 101704339

Informations de publication

Date de publication:
04 2021
Historique:
received: 01 05 2020
revised: 26 01 2021
accepted: 27 01 2021
entrez: 11 4 2021
pubmed: 12 4 2021
medline: 26 11 2021
Statut: ppublish

Résumé

Epidemiological evidence on short-term association between ambient carbon monoxide (CO) and mortality is inconclusive and limited to single cities, regions, or countries. Generalisation of results from previous studies is hindered by potential publication bias and different modelling approaches. We therefore assessed the association between short-term exposure to ambient CO and daily mortality in a multicity, multicountry setting. We collected daily data on air pollution, meteorology, and total mortality from 337 cities in 18 countries or regions, covering various periods from 1979 to 2016. All included cities had at least 2 years of both CO and mortality data. We estimated city-specific associations using confounder-adjusted generalised additive models with a quasi-Poisson distribution, and then pooled the estimates, accounting for their statistical uncertainty, using a random-effects multilevel meta-analytical model. We also assessed the overall shape of the exposure-response curve and evaluated the possibility of a threshold below which health is not affected. Overall, a 1 mg/m This international study is by far the largest epidemiological investigation on short-term CO-related mortality. We found significant associations between ambient CO and daily mortality, even at levels well below current air quality guidelines. Further studies are warranted to disentangle its independent effect from other traffic-related pollutants. EU Horizon 2020, UK Medical Research Council, and Natural Environment Research Council.

Sections du résumé

BACKGROUND
Epidemiological evidence on short-term association between ambient carbon monoxide (CO) and mortality is inconclusive and limited to single cities, regions, or countries. Generalisation of results from previous studies is hindered by potential publication bias and different modelling approaches. We therefore assessed the association between short-term exposure to ambient CO and daily mortality in a multicity, multicountry setting.
METHODS
We collected daily data on air pollution, meteorology, and total mortality from 337 cities in 18 countries or regions, covering various periods from 1979 to 2016. All included cities had at least 2 years of both CO and mortality data. We estimated city-specific associations using confounder-adjusted generalised additive models with a quasi-Poisson distribution, and then pooled the estimates, accounting for their statistical uncertainty, using a random-effects multilevel meta-analytical model. We also assessed the overall shape of the exposure-response curve and evaluated the possibility of a threshold below which health is not affected.
FINDINGS
Overall, a 1 mg/m
INTERPRETATION
This international study is by far the largest epidemiological investigation on short-term CO-related mortality. We found significant associations between ambient CO and daily mortality, even at levels well below current air quality guidelines. Further studies are warranted to disentangle its independent effect from other traffic-related pollutants.
FUNDING
EU Horizon 2020, UK Medical Research Council, and Natural Environment Research Council.

Identifiants

DOI: 10.1016/S2542-5196(21)00026-7 PMID: 33838734
pubmed: 33838734
pii: S2542-5196(21)00026-7
doi: 10.1016/S2542-5196(21)00026-7
pii:
doi:

Substances chimiques

Air Pollutants 0
Carbon Monoxide 7U1EE4V452

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e191-e199

Subventions

Organisme : Medical Research Council
ID : MR/R013349/1
Pays : United Kingdom

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests We declare no competing interests.

Auteurs

Kai Chen (K)

Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, USA. Electronic address: kai.chen@yale.edu.

Susanne Breitner (S)

Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany.

Kathrin Wolf (K)

Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.

Massimo Stafoggia (M)

Department of Epidemiology, Lazio Regional Health Service, Rome, Italy.

Francesco Sera (F)

Department of Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, UK; Department of Statistics, Computer Science and Applications "G. Parenti", University of Florence, Florence, Italy.

Ana M Vicedo-Cabrera (AM)

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; Oeschger Center for Climate Change Research, University of Bern, Bern, Switzerland.

Yuming Guo (Y)

Climate, Air Quality Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

Shilu Tong (S)

Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; School of Public Health, Institute of Environment and Population Health, Anhui Medical University, Hefei, China; School of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD, Australia; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.

Eric Lavigne (E)

Air Health Science Division, Health Canada, Ottawa, ON, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.

Patricia Matus (P)

Department of Public Health, Universidad de los Andes, Santiago, Chile.

Nicolás Valdés (N)

Faculty of Nursing and Midwifery, Universidad de los Andes, Santiago, Chile.

Haidong Kan (H)

School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, China; Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP3), Fudan University, Shanghai, China.

Jouni J K Jaakkola (JJK)

Center for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; Finnish Meteorological Institute, Helsinki, Finland.

Niilo R I Ryti (NRI)

Center for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland.

Veronika Huber (V)

Department of Physical, Chemical and Natural Systems, Universidad Pablo de Olavide, Seville, Spain; Potsdam Institute for Climate Impact Research, Potsdam, Germany.

Matteo Scortichini (M)

Department of Epidemiology, Lazio Regional Health Service, Rome, Italy.

Masahiro Hashizume (M)

Department of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Yasushi Honda (Y)

Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.

Baltazar Nunes (B)

Department of Epidemiology, Instituto Nacional de Saúde Dr Ricardo Jorge, Lisbon, Portugal; Centro de Investigação em Saúde Pública, Escola Nacional de Saúde Pública, Universidade NOVA de Lisboa, Lisbon, Portugal.

Joana Madureira (J)

Department of Enviromental Health, Instituto Nacional de Saúde Dr Ricardo Jorge, Porto, Portugal; EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.

Iulian Horia Holobâcă (IH)

Faculty of Geography, Babes-Bolay University, Cluj-Napoca, Romania.

Simona Fratianni (S)

Department of Earth Sciences, University of Torino, Turin, Italy.

Ho Kim (H)

Graduate School of Public Health, Seoul National University, Seoul, South Korea.

Whanhee Lee (W)

Graduate School of Public Health, Seoul National University, Seoul, South Korea.

Aurelio Tobias (A)

Institute of Environmental Assessment and Water Research, Spanish Council for Scientific Research, Barcelona, Spain; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.

Carmen Íñiguez (C)

Department of Statistics and Computational Research, University of Valencia, Valencia, Spain; Ciberesp, Madrid, Spain.

Bertil Forsberg (B)

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Christofer Åström (C)

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Martina S Ragettli (MS)

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

Yue-Liang Leon Guo (YL)

Environmental and Occupational Medicine, National Taiwan University and NTU Hospital, Taipei, Taiwan; National Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan.

Bing-Yu Chen (BY)

National Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan.

Shanshan Li (S)

Climate, Air Quality Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

Ai Milojevic (A)

Department of Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, UK.

Antonella Zanobetti (A)

Department of Environmental Health, Harvard T H Chan School of Public Health, Boston, MA, USA.

Joel Schwartz (J)

Department of Environmental Health, Harvard T H Chan School of Public Health, Boston, MA, USA.

Michelle L Bell (ML)

School of the Environment, Yale University, New Haven, CT, USA.

Antonio Gasparrini (A)

Department of Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, UK; Centre for Statistical Methodology, London School of Hygiene & Tropical Medicine, London, UK; Centre on Climate Change and Planetary Health, London School of Hygiene & Tropical Medicine, London, UK.

Alexandra Schneider (A)

Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants atmosphériques › Ambient carbon monoxide and daily mortality: a...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Pollution de l'air › Ambient carbon monoxide and daily mortality: a...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Monoxyde de carbone › Ambient carbon monoxide and daily mortality: a...
questionsmedicales.fr › Maladies cardiovasculaires › Ambient carbon monoxide and daily mortality: a...
questionsmedicales.fr › Régions géographiques › Villes › Ambient carbon monoxide and daily mortality: a...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Ambient carbon monoxide and daily mortality: a...