National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIa. The 2020 Clinical Implementation and Early Diagnosis Working Group Report.
Allogeneic hematopoietic cell transplantation
Chronic graft-versus-host disease
Consensus
Early diagnosis
Journal
Transplantation and cellular therapy
ISSN: 2666-6367
Titre abrégé: Transplant Cell Ther
Pays: United States
ID NLM: 101774629
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
31
03
2021
accepted:
31
03
2021
pubmed:
12
4
2021
medline:
16
7
2021
entrez:
11
4
2021
Statut:
ppublish
Résumé
Recognition of the earliest signs and symptoms of chronic graft-versus-host disease (GVHD) that lead to severe manifestations remains a challenge. The standardization provided by the National Institutes of Health (NIH) 2005 and 2014 consensus projects has helped improve diagnostic accuracy and severity scoring for clinical trials, but utilization of these tools in routine clinical practice is variable. Additionally, when patients meet the NIH diagnostic criteria, many already have significant morbidity and possibly irreversible organ damage. The goals of this early diagnosis project are 2-fold. First, we provide consensus recommendations regarding implementation of the current NIH diagnostic guidelines into routine transplant care, outside of clinical trials, aiming to enhance early clinical recognition of chronic GVHD. Second, we propose directions for future research efforts to enable discovery of new, early laboratory as well as clinical indicators of chronic GVHD, both globally and for highly morbid organ-specific manifestations. Identification of early features of chronic GVHD that have high positive predictive value for progression to more severe manifestations of the disease could potentially allow for future pre-emptive clinical trials.
Identifiants
pubmed: 33839317
pii: S2666-6367(21)00824-1
doi: 10.1016/j.jtct.2021.03.033
pmc: PMC8803210
mid: NIHMS1757220
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
545-557Subventions
Organisme : CSRD VA
ID : IK2 CX001785
Pays : United States
Informations de copyright
Copyright © 2021 The American Society for Transplantation and Cellular Therapy. All rights reserved.
Références
Biol Blood Marrow Transplant. 2018 Aug;24(8):1692-1698
pubmed: 29753161
Biol Blood Marrow Transplant. 2018 Mar;24(3):555-562
pubmed: 29133250
Proc Natl Acad Sci U S A. 2018 May 1;115(18):4583-4588
pubmed: 29666252
Eur Respir J. 2019 May 2;53(5):
pubmed: 30846475
Biol Blood Marrow Transplant. 2015 Aug;21(8):1524-8
pubmed: 25963919
J Clin Invest. 2017 Jun 30;127(7):2452-2463
pubmed: 28665299
Ann Am Thorac Soc. 2020 Oct;17(10):1329-1333
pubmed: 32614241
Blood. 2019 Jul 18;134(3):304-316
pubmed: 31043425
J Heart Lung Transplant. 1996 Feb;15(2):175-81
pubmed: 8672521
Biol Blood Marrow Transplant. 2014 Apr;20(4):556-63
pubmed: 24447907
Eur Respir J. 2014 Dec;44(6):1479-503
pubmed: 25359357
Ocul Surf. 2019 Jul;17(3):589-614
pubmed: 30965123
Biol Blood Marrow Transplant. 2002;8(8):444-52
pubmed: 12234170
Br J Ophthalmol. 2015 Feb;99(2):160-5
pubmed: 25138762
Eye Contact Lens. 2021 Jan 1;47(1):8-14
pubmed: 32097186
Blood. 2011 Apr 28;117(17):4651-7
pubmed: 21355084
J Allergy Clin Immunol. 2018 Feb;141(2):697-703.e8
pubmed: 28716387
Biol Blood Marrow Transplant. 2012 Mar;18(3):348-71
pubmed: 22178693
Biol Blood Marrow Transplant. 2016 Mar;22(3):449-55
pubmed: 26541363
Transplant Cell Ther. 2021 Jul;27(7):616.e1-616.e6
pubmed: 33781975
J Heart Lung Transplant. 2012 Dec;31(12):1288-92
pubmed: 23102913
J Oncol Pract. 2006 Sep;2(5):228-30
pubmed: 20859340
Bone Marrow Transplant. 2018 Nov;53(11):1401-1415
pubmed: 29872128
Future Oncol. 2020 Jun;16(18):1225-1227
pubmed: 32356460
Br J Ophthalmol. 1999 Oct;83(10):1125-30
pubmed: 10502571
Am J Respir Crit Care Med. 2004 Feb 15;169(4):468-72
pubmed: 14670802
Bone Marrow Transplant. 2014 Dec;49(12):1521-7
pubmed: 25243619
Bone Marrow Transplant. 2008 Jul;42(1):43-9
pubmed: 18347569
Am J Transplant. 2018 Jan;18(1):145-153
pubmed: 28719135
Biol Blood Marrow Transplant. 2005 Dec;11(12):945-56
pubmed: 16338616
Biol Blood Marrow Transplant. 2011 Nov;17(11):1619-29
pubmed: 21536143
Blood. 2017 Nov 23;130(21):2243-2250
pubmed: 28924018
JAMA Oncol. 2016 Dec 1;2(12):1583-1589
pubmed: 27532508
Acta Derm Venereol. 2017 Jul 5;Suppl 218:5-13
pubmed: 28676880
Clin Transplant. 2015 Dec;29(12):1133-9
pubmed: 26383085
Sensors (Basel). 2020 Oct 27;20(21):
pubmed: 33120974
Sci Rep. 2017 Sep 6;7(1):10720
pubmed: 28878217
Arch Dermatol. 2008 Sep;144(9):1229-31
pubmed: 18794477
Am J Transplant. 2020 Aug;20(8):2198-2205
pubmed: 32034974
Biol Blood Marrow Transplant. 2010 Jun;16(6):782-91
pubmed: 20060053
Cornea. 2015 Aug;34(8):911-6
pubmed: 26075459
Transplantation. 2005 May 27;79(10):1411-6
pubmed: 15912112
Biol Blood Marrow Transplant. 2019 Feb;25(2):279-286
pubmed: 30219700
Eur Respir J. 2018 May 3;51(5):
pubmed: 29650555
Ophthalmology. 2015 Aug;122(8):1669-74
pubmed: 26001816
Am J Respir Crit Care Med. 2015 Jun 1;191(11):1242-9
pubmed: 25835160
Eur J Oncol Nurs. 2020 Apr;45:101723
pubmed: 32062362
Biol Blood Marrow Transplant. 2020 May;26(5):943-948
pubmed: 31821885
Bone Marrow Transplant. 2014 Jan;49(1):49-54
pubmed: 23955633
Eur Respir J. 2005 Nov;26(5):948-68
pubmed: 16264058
N Engl J Med. 2016 Jan 7;374(1):43-53
pubmed: 26735993
J Invest Dermatol. 2021 Apr;141(4):924-927.e2
pubmed: 32950506
Ocul Surf. 2019 Jan;17(1):160-166
pubmed: 30399438
Bone Marrow Transplant. 2013 Jun;48(6):819-24
pubmed: 23208317
Haematologica. 2019 May;104(5):1084-1092
pubmed: 30514795
Biol Blood Marrow Transplant. 2019 Sep;25(9):1851-1858
pubmed: 31129353
Sci Transl Med. 2010 Jan 6;2(13):13ra2
pubmed: 20371463
Ann Am Thorac Soc. 2016 Nov;13(11):1932-1939
pubmed: 27513368
J Cutan Pathol. 2015 Jan;42(1):39-45
pubmed: 25393781
J Clin Invest. 2015 Jul 1;125(7):2677-89
pubmed: 26053664
Haematologica. 2018 Nov;103(11):1915-1924
pubmed: 29954931
Blood. 2017 Jan 5;129(1):30-37
pubmed: 27821503
Am J Respir Crit Care Med. 2005 Aug 1;172(3):379-83
pubmed: 15894603
Eur J Cancer Care (Engl). 2016 May;25(3):402-18
pubmed: 26215187
Blood Adv. 2020 Jan 14;4(1):40-46
pubmed: 31899796
Invest Ophthalmol Vis Sci. 2016 Feb;57(2):746-58
pubmed: 26927568
J Heart Lung Transplant. 2003 Apr;22(4):427-32
pubmed: 12681420
Bone Marrow Transplant. 2020 Sep;55(9):1851-1853
pubmed: 32042103
Clin Cancer Res. 2015 May 1;21(9):2020-8
pubmed: 25348512
Ann Am Thorac Soc. 2016 Nov;13(11):1883-1884
pubmed: 27831809
Biomed Microdevices. 2019 Aug 15;21(4):81
pubmed: 31418068
Br J Dermatol. 2019 Oct;181(4):829-831
pubmed: 30927259
JAMA. 2009 Jul 15;302(3):306-14
pubmed: 19602690
Biol Blood Marrow Transplant. 2020 May;26(5):e113-e127
pubmed: 32028026
Blood. 2013 Jul 18;122(3):463-5
pubmed: 23869081
J Heart Lung Transplant. 2002 Mar;21(3):297-310
pubmed: 11897517
Eur Respir J. 2018 Aug 2;52(2):
pubmed: 29853492
Blood. 2011 Mar 17;117(11):3214-9
pubmed: 21263156
Biol Blood Marrow Transplant. 2017 Feb;23(2):211-234
pubmed: 27713092
Graefes Arch Clin Exp Ophthalmol. 2017 Sep;255(9):1771-1778
pubmed: 28528377
Haematologica. 2015 Sep;100(9):1228-36
pubmed: 26088932
Bone Marrow Transplant. 2019 Apr;54(4):616-619
pubmed: 30287938
Blood. 2013 Mar 7;121(10):1886-95
pubmed: 23303823
Biol Blood Marrow Transplant. 2015 Sep;21(9):1687-91
pubmed: 26033283
Biol Blood Marrow Transplant. 2015 Jun;21(6):984-99
pubmed: 25796139
Biol Blood Marrow Transplant. 2015 Feb;21(2):266-74
pubmed: 25445023
Haematologica. 2018 Oct;103(10):1698-1707
pubmed: 29903762
Blood. 2017 Jul 20;130(3):360-367
pubmed: 28495794
Cornea. 2014 Dec;33(12):1252-6
pubmed: 25343699
Blood. 2013 Jun 20;121(25):5098-103
pubmed: 23547053
Transplant Cell Ther. 2021 Jun;27(6):448-451
pubmed: 33785366
Cell. 2018 Sep 6;174(6):1373-1387.e19
pubmed: 30193111
JAMA. 2019 Jan 22;321(3):306-307
pubmed: 30667494
Bone Marrow Transplant. 2018 Apr;53(4):490-494
pubmed: 29330389
Arch Dermatol. 2009 Mar;145(3):337-8
pubmed: 19289778
Ocul Surf. 2020 Jan;18(1):80-97
pubmed: 31606460
Arch Ophthalmol. 2000 May;118(5):615-21
pubmed: 10815152
Biol Blood Marrow Transplant. 2016 May;22(5):925-31
pubmed: 26748162
Mol Vis. 2011;17:2533-43
pubmed: 22025888
Biol Blood Marrow Transplant. 2020 Aug;26(8):1459-1468
pubmed: 32434056
Support Care Cancer. 2020 Mar;28(3):1223-1231
pubmed: 31222392
Arthritis Rheumatol. 2014 Apr;66(4):1044-52
pubmed: 24757155
Biol Blood Marrow Transplant. 2008 Jun;14(6):641-50
pubmed: 18489989
Ocul Surf. 2020 Jan;18(1):98-107
pubmed: 31605785
JCI Insight. 2020 Aug 20;5(16):
pubmed: 32814713
Arch Dermatol. 2009 Aug;145(8):918-22
pubmed: 19687424
BMC Health Serv Res. 2019 May 24;19(1):332
pubmed: 31126277
Biol Blood Marrow Transplant. 2015 Mar;21(3):389-401.e1
pubmed: 25529383
Bone Marrow Transplant. 2016 Aug;51(8):1062-5
pubmed: 27042834
Biol Blood Marrow Transplant. 2014 Oct;20(10):1592-8
pubmed: 24954547
Biol Blood Marrow Transplant. 2015 Jul;21(7):1167-87
pubmed: 25838185
Bone Marrow Transplant. 2019 Jan;54(1):76-84
pubmed: 30089900
Bone Marrow Transplant. 2021 Apr;56(4):989-991
pubmed: 33279941
J Invest Dermatol. 2017 Jan;137(1):62-70
pubmed: 27640094
Haematologica. 2018 Sep;103(9):1535-1541
pubmed: 29858386
Haematologica. 2019 Jan;104(1):189-196
pubmed: 30237265
Blood. 2016 Mar 17;127(11):1502-8
pubmed: 26764356
N Engl J Med. 2014 Jan 30;370(5):433-43
pubmed: 24350901
Biol Blood Marrow Transplant. 2006 Mar;12(3):252-66
pubmed: 16503494
Biol Blood Marrow Transplant. 2019 Apr;25(4):800-809
pubmed: 30521974
Biol Blood Marrow Transplant. 2019 Mar;25(3):599-605
pubmed: 30296479
Am Soc Clin Oncol Educ Book. 2018 May 23;38:540-545
pubmed: 30231354
Transplant Cell Ther. 2021 Mar;27(3):271.e1-271.e8
pubmed: 33781538
J Infect Dis. 2006 Jun 15;193(12):1619-25
pubmed: 16703503
Ultrasound Med Biol. 2015 Nov;41(11):2806-19
pubmed: 26259888
Transplantation. 2007 Mar 15;83(5):554-60
pubmed: 17353773
Biol Blood Marrow Transplant. 2012 Jul;18(7):1044-54
pubmed: 22155140
Support Care Cancer. 2019 Jun;27(6):2103-2112
pubmed: 30232587
Bone Marrow Transplant. 2018 May;53(5):576-583
pubmed: 29335633
Biol Blood Marrow Transplant. 2019 Jul;25(7):1416-1423
pubmed: 30796997
Biol Blood Marrow Transplant. 2015 Jun;21(6):1127-31
pubmed: 25687798
Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4836-4846
pubmed: 28973330
Chest. 2018 Jul;154(1):157-168
pubmed: 29275133