Methodological Consideration on Monitoring Refractory Intracranial Hypertension and Autonomic Nervous System Activity.


Journal

Acta neurochirurgica. Supplement
ISSN: 0065-1419
Titre abrégé: Acta Neurochir Suppl
Pays: Austria
ID NLM: 100962752

Informations de publication

Date de publication:
2021
Historique:
entrez: 11 4 2021
pubmed: 12 4 2021
medline: 8 6 2021
Statut: ppublish

Résumé

Refractory intracranial hypertension (RIH) refers to a dramatic increase in intracranial pressure (ICP) that cannot be controlled by treatment and leads to patient death. Detrimental sequelae of raised ICP in acute brain injury (ABI) are unclear because the underlying physiopathological mechanisms of raised ICP have not been sufficiently investigated. Recent reports have shown that autonomic activity is altered during changes in ICP. The aim of our study was to evaluate the feasibility of assessing autonomic activity during RIH with our adopted methodology. We selected 24 ABI patients for retrospective review who developed RIH. They were monitored based on ICP, arterial blood pressure, and electrocardiogram using ICM+ software. Secondary parameters reflecting autonomic activity were computed in time and frequency domains through the continuous measurement of heart rate variability and baroreflex sensitivity. The results of the analysis will be presented later in a full paper. This preliminary analysis shows the feasibility of the adopted methodology.

Identifiants

pubmed: 33839847
doi: 10.1007/978-3-030-59436-7_41
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

211-215

Références

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Auteurs

Marta Fedriga (M)

Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. marta.fedriga@gmail.com.
Department of Anesthesia, Critical Care and Emergency, Spedali Civili University Hospital, Brescia, Italy. marta.fedriga@gmail.com.

András Czigler (A)

Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Department of Neurosurgery and Szentagothai Research Center, University of Pecs, Pecs, Hungary.

Nathalie Nasr (N)

Département de Neurologie CHU de Toulouse, Université de Toulouse III, Toulouse, France.

Frederick A Zeiler (FA)

Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Biomedical Engineering, Faculty of Engineering, University of Manitoba, Winnipeg, MB, Canada.
Division of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, UK.

Erta Beqiri (E)

Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Department of Physiology and Transplantation, Milan University, Milan, Italy.

Stefan Wolf (S)

Department of Neurosurgery Charite Hospital, Berlin, Germany.

Shirin K Frisvolf (SK)

Department of Intensive Care, University Hospital, Tromso, Norway.

Peter Smielewski (P)

Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

Marek Czosnyka (M)

Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

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