Intravenous abciximab as a rescue therapy for immediate reocclusion after successful mechanical thrombectomy in acute ischemic stroke patients.


Journal

Platelets
ISSN: 1369-1635
Titre abrégé: Platelets
Pays: England
ID NLM: 9208117

Informations de publication

Date de publication:
17 Feb 2022
Historique:
pubmed: 13 4 2021
medline: 30 3 2022
entrez: 12 4 2021
Statut: ppublish

Résumé

Immediate reocclusion after mechanical thrombectomy (MT) for acute ischemic stroke (AIS) is a rare but devastating condition associated with poor functional outcome. The aim of this study was to gain insights into the mechanisms underlying immediate reocclusion, and to evaluate the efficacy and safety of the glycoprotein IIb/IIIa antagonist abciximab, for its treatment. Clinical data were collected from April 2015 to April 2019 in a monocentric prospective registry of AIS patients treated by MT. All patients with immediate reocclusion were retrospectively selected and subdivided into 2 groups according to abciximab treatment status.

Identifiants

pubmed: 33840346
doi: 10.1080/09537104.2021.1894326
doi:

Substances chimiques

Platelet Aggregation Inhibitors 0
Abciximab X85G7936GV

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

285-290

Auteurs

François Delvoye (F)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.
University of Liege, Belgium.

Stephane Loyau (S)

Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.

Julien Labreuche (J)

Lille, France.

Guillaume Taylor (G)

Rothschild Foundation Hospital, Intensive Care Department, Paris, France.

Benjamin Maier (B)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.
Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.

Michel Piotin (M)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.
Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.

Raphael Blanc (R)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.
Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.

Simon Escalard (S)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.

Lucas Di Meglio (L)

Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.

Malek Ben Maacha (M)

Clinical Research Unit, Rothschild Foundation Hospital, Paris, France.

Hocine Redjem (H)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.

Stanislas Smajda (S)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.

Gabriele Ciccio (G)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.

Solène Hébert (S)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.

Candice Sabben (C)

Rothschild Foundation Hospital, Neurology Department, Paris, France.

Martine Jandrot-Perrus (M)

Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.

Alain Maertens De Noordhout (A)

University of Liege, Belgium.

Mikael Mazighi (M)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.
Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.
Université De Paris, France.
DHU Neurovasc.

Benoit Ho-Tin-Noé (B)

Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.

Jean-Philippe Desilles (JP)

Rothschild Foundation Hospital, Interventional Neuroradiology Department, Paris, France.
Laboratory of Vascular Translational Science, U1148 INSERM, Université De Paris, Paris, France.
Université De Paris, France.

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Classifications MeSH