A comparative study of desflurane versus sevoflurane in obese patients: Effect on recovery profile.
Anesthesia for obese
desflurane
inhalational agents
recovery characteristics
sevoflurane
Journal
Journal of anaesthesiology, clinical pharmacology
ISSN: 0970-9185
Titre abrégé: J Anaesthesiol Clin Pharmacol
Pays: India
ID NLM: 9516972
Informations de publication
Date de publication:
Historique:
received:
15
09
2019
revised:
03
03
2020
accepted:
12
03
2020
entrez:
12
4
2021
pubmed:
13
4
2021
medline:
13
4
2021
Statut:
ppublish
Résumé
Anesthesia in obese patients is difficult due to associated comorbidities and altered physiology. Desflurane and sevoflurane have a low fat-blood solubility coefficient and are better suited in these patients to achieve a rapid emergence. We studied BIS guided drug titration to compare the postoperative recovery characteristics and cognitive function of desflurane versus sevoflurane in obese patients undergoing laparoscopic abdominal surgeries. After institutional ethics committee approval and written informed consent, sixty obese patients (BMI ≥30 kg/m Difference of time taken for eye opening on verbal command, sustained head lift for 5 s, and extubation and orientation to time, place, and person was not significant between both anesthetic groups. Patients in sevoflurane group took significantly ( Both desflurane and sevoflurane have similar recovery profile in obese patients when anesthetic concentration is carefully titrated. Reversal of cognitive function is significantly earlier in obese patients anesthetized with sevoflurane.
Sections du résumé
BACKGROUND AND AIMS
OBJECTIVE
Anesthesia in obese patients is difficult due to associated comorbidities and altered physiology. Desflurane and sevoflurane have a low fat-blood solubility coefficient and are better suited in these patients to achieve a rapid emergence. We studied BIS guided drug titration to compare the postoperative recovery characteristics and cognitive function of desflurane versus sevoflurane in obese patients undergoing laparoscopic abdominal surgeries.
MATERIAL AND METHODS
METHODS
After institutional ethics committee approval and written informed consent, sixty obese patients (BMI ≥30 kg/m
RESULTS
RESULTS
Difference of time taken for eye opening on verbal command, sustained head lift for 5 s, and extubation and orientation to time, place, and person was not significant between both anesthetic groups. Patients in sevoflurane group took significantly (
CONCLUSION
CONCLUSIONS
Both desflurane and sevoflurane have similar recovery profile in obese patients when anesthetic concentration is carefully titrated. Reversal of cognitive function is significantly earlier in obese patients anesthetized with sevoflurane.
Identifiants
pubmed: 33840938
doi: 10.4103/joacp.JOACP_307_19
pii: JOACP-36-541
pmc: PMC8022057
doi:
Types de publication
Journal Article
Langues
eng
Pagination
541-545Informations de copyright
Copyright: © 2021 Journal of Anaesthesiology Clinical Pharmacology.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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