Harnessing biomaterials for therapeutic strategies against COVID-19.


Journal

Emergent materials
ISSN: 2522-574X
Titre abrégé: Emergent Mater
Pays: Switzerland
ID NLM: 101752456

Informations de publication

Date de publication:
2021
Historique:
received: 08 12 2020
accepted: 24 01 2021
pubmed: 13 4 2021
medline: 13 4 2021
entrez: 12 4 2021
Statut: ppublish

Résumé

With the emergence of the coronavirus disease 2019 (COVID-19), the world is experiencing a profound human health crisis. The number of infections and deaths due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to increase every minute, pinpointing major shortcomings in our ability to prevent viral outbreaks. Although several COVID-19 vaccines have been recently approved for emergency use, therapeutic options remain limited, and their long-term potency has yet to be validated. Biomaterials science has a pivotal role to play in pushing the boundaries of emerging technologies for antiviral research and treatment. In this perspective, we discuss how biomaterials can be harnessed to develop accurate COVID-19 infection models, enhance antiviral drug delivery, foster new antiviral strategies, and boost vaccine efficacy. These efforts will not only contribute to stop or mitigate the current pandemic but will also provide unorthodox platforms to understand, prevent, and protect us from future viral outbreaks.

Identifiants

pubmed: 33842840
doi: 10.1007/s42247-021-00171-z
pii: 171
pmc: PMC8022295
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

9-18

Informations de copyright

© Qatar University and Springer Nature Switzerland AG 2021.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing interests.

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Auteurs

Thibault Colombani (T)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115 USA.

Zachary J Rogers (ZJ)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115 USA.

Loek J Eggermont (LJ)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115 USA.

Sidi A Bencherif (SA)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115 USA.
Department of Bioengineering, Northeastern University, Boston, MA 02115 USA.
Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138 USA.
Biomechanics and Bioengineering (BMBI), UTC CNRS UMR 7338, University of Technology of Compiègne, Sorbonne University, 60203 Compiègne, France.

Classifications MeSH