Serological evidence of West Nile virus infection in human populations and domestic birds in the Northwest of Morocco.
Bird
Human
Morocco
Serology
Virus neutralization test
West Nile virus
Journal
Comparative immunology, microbiology and infectious diseases
ISSN: 1878-1667
Titre abrégé: Comp Immunol Microbiol Infect Dis
Pays: England
ID NLM: 7808924
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
25
01
2021
revised:
08
03
2021
accepted:
15
03
2021
pubmed:
13
4
2021
medline:
25
6
2021
entrez:
12
4
2021
Statut:
ppublish
Résumé
West Nile virus (WNV) was recently detected in Culex pipiens mosquitoes in Morocco. The aim of this study was to evaluate the seroprevalence of WNV in humans and in domestic birds in two regions of Morocco by the detection of IgG antibodies. Blood samples were obtained from 91 human patients and 92 domestic birds from September to December 2019. All study samples were tested using competitive enzyme-linked immunosorbent assay (cELISA) and WNV neutralization tests (VNT) were performed on positive sera. Of all samples, 4 (4.39 %) humans and 4 (4.34 %) birds were found to be seropositive for flaviviruses by the cELISA test. The VNT revealed that three of the four human samples detected positive by cELISA contained neutralizing antibodies against WNV. Two bird samples were confirmed positive by VNT. These results show a significant seroprevalence of anti-WNV antibodies and therefore suggest the active circulation and exposure of human and bird populations in the northwest of Morocco.
Identifiants
pubmed: 33845402
pii: S0147-9571(21)00038-2
doi: 10.1016/j.cimid.2021.101646
pii:
doi:
Substances chimiques
Antibodies, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
101646Informations de copyright
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