Efficacy of broflanilide (VECTRON T500), a new meta-diamide insecticide, for indoor residual spraying against pyrethroid-resistant malaria vectors.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
12 04 2021
Historique:
received: 01 12 2020
accepted: 18 03 2021
entrez: 13 4 2021
pubmed: 14 4 2021
medline: 3 11 2021
Statut: epublish

Résumé

The rotational use of insecticides with different modes of action for indoor residual spraying (IRS) is recommended for improving malaria vector control and managing insecticide resistance. Insecticides with new chemistries are urgently needed. Broflanilide is a newly discovered insecticide under consideration. We investigated the efficacy of a wettable powder (WP) formulation of broflanilide (VECTRON T500) for IRS on mud and cement wall substrates in laboratory and experimental hut studies against pyrethroid-resistant malaria vectors in Benin, in comparison with pirimiphos-methyl CS (Actellic 300CS). There was no evidence of cross-resistance to pyrethroids and broflanilide in CDC bottle bioassays. In laboratory cone bioassays, broflanilide WP-treated substrates killed > 80% of susceptible and pyrethroid-resistant An. gambiae sl for 6-14 months. At application rates of 100 mg/m

Identifiants

pubmed: 33846394
doi: 10.1038/s41598-021-86935-3
pii: 10.1038/s41598-021-86935-3
pmc: PMC8042056
doi:

Substances chimiques

3-benzamido-N-(4-(perfluoropropan-2-yl)phenyl)benzamide 0
Benzamides 0
Insecticides 0
Pyrethrins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

7976

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Auteurs

Corine Ngufor (C)

London School of Hygiene and Tropical Medicine (LSHTM), London, UK. corine.ngufor@lshtm.ac.uk.
Centre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin. corine.ngufor@lshtm.ac.uk.
Panafrican Malaria Vector Research Consortium (PAMVERC), Cotonou, Benin. corine.ngufor@lshtm.ac.uk.

Renaud Govoetchan (R)

London School of Hygiene and Tropical Medicine (LSHTM), London, UK.
Centre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin.
Panafrican Malaria Vector Research Consortium (PAMVERC), Cotonou, Benin.

Augustin Fongnikin (A)

Centre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin.
Panafrican Malaria Vector Research Consortium (PAMVERC), Cotonou, Benin.

Estelle Vigninou (E)

Centre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin.

Thomas Syme (T)

London School of Hygiene and Tropical Medicine (LSHTM), London, UK.
Centre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin.
Panafrican Malaria Vector Research Consortium (PAMVERC), Cotonou, Benin.

Martin Akogbeto (M)

Centre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin.

Mark Rowland (M)

London School of Hygiene and Tropical Medicine (LSHTM), London, UK.
Panafrican Malaria Vector Research Consortium (PAMVERC), Cotonou, Benin.

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Classifications MeSH