Inhibitory effects of terrein on lung cancer cell metastasis and angiogenesis.
A549 Cells
Animals
Aspergillus
/ chemistry
Carcinoma, Non-Small-Cell Lung
/ blood supply
Cell Adhesion
/ drug effects
Cell Movement
/ drug effects
Chlorocebus aethiops
Cyclopentanes
/ isolation & purification
Humans
Lung Neoplasms
/ blood supply
Neovascularization, Pathologic
/ drug therapy
Vascular Endothelial Growth Factor A
/ metabolism
Vascular Endothelial Growth Factor Receptor-2
/ metabolism
Vero Cells
terrein
non‑small cell lung cancer
migration
invasion
angiogenesis
metastasis
Journal
Oncology reports
ISSN: 1791-2431
Titre abrégé: Oncol Rep
Pays: Greece
ID NLM: 9422756
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
28
10
2020
accepted:
01
03
2021
entrez:
13
4
2021
pubmed:
14
4
2021
medline:
4
11
2021
Statut:
ppublish
Résumé
Cancer metastasis is the leading cause of mortality in cancer patients. Over 70% of lung cancer patients are diagnosed at advanced or metastatic stages, and this results in an increased incidence of mortality. Terrein is a secondary bioactive fungal metabolite isolated from
Identifiants
pubmed: 33846818
doi: 10.3892/or.2021.8045
pii: 94
pmc: PMC8047749
doi:
pii:
Substances chimiques
Cyclopentanes
0
VEGFA protein, human
0
Vascular Endothelial Growth Factor A
0
terrein
3I47HPE16N
KDR protein, human
EC 2.7.10.1
Vascular Endothelial Growth Factor Receptor-2
EC 2.7.10.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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