Quantitative X-ray phase contrast computed tomography with grating interferometry : Biomedical applications of quantitative X-ray grating-based phase contrast computed tomography.
CT
Computed tomography
Effective atomic number
Electron density
Grating interferometer
Grating interferometry
Phase contrast imaging
Phase contrast tomography
Quantitative imaging
X-ray imaging
Journal
European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
01
12
2020
accepted:
11
02
2021
pubmed:
14
4
2021
medline:
12
11
2021
entrez:
13
4
2021
Statut:
ppublish
Résumé
The ability of biomedical imaging data to be of quantitative nature is getting increasingly important with the ongoing developments in data science. In contrast to conventional attenuation-based X-ray imaging, grating-based phase contrast computed tomography (GBPC-CT) is a phase contrast micro-CT imaging technique that can provide high soft tissue contrast at high spatial resolution. While there is a variety of different phase contrast imaging techniques, GBPC-CT can be applied with laboratory X-ray sources and enables quantitative determination of electron density and effective atomic number. In this review article, we present quantitative GBPC-CT with the focus on biomedical applications.
Identifiants
pubmed: 33846846
doi: 10.1007/s00259-021-05259-6
pii: 10.1007/s00259-021-05259-6
pmc: PMC8566444
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
4171-4188Informations de copyright
© 2021. The Author(s).
Références
Fitzgerald R. Phase-sensitive X-ray imaging. Phys Today 2000;53(7):23–26. https://doi.org/10.1063/1.1292471 .
Momose A. Recent advances in X-ray phase imaging. Jap J Appl Phys 2005;44:6355–6367. https://doi.org/10.1143/JJAP.44.6355 .
Zhou SA, Brahme A. Development of phase-contrast X-ray imaging techniques and potential medical applications. Phys Med 2008;24(3):129–48. https://doi.org/10.1016/j.ejmp.2008.05.006 .
pubmed: 18602852
Nugent KA. Coherent methods in the X-ray sciences. Adv Phys 2010;59:1, 1–99. https://doi.org/10.1080/00018730903270926 .
Pfeiffer F. 2012. Milestones and basic principles of grating-based x-ray and neutron phase-contrast imaging. AIP Conf Proc 1466(2). https://doi.org/10.1063/1.4742261 .
Bravin A, Coan P, Suortti P. X-ray phase-contrast imaging: from pre-clinical applications towards clinics. Phys Med Biol 2013;58(1):R1–35. https://doi.org/10.1088/0031-9155/58/1/R1 .
pubmed: 23220766
Pfeiffer F, Herzen J, Willner M, Chabior M, Auweter S, Reiser M, Bamberg F. Grating-based X-ray phase contrast for biomedical imaging applications. Z Med Phys 2013;3:176–85. https://doi.org/10.1016/j.zemedi.2013.02.002 .
Wilkins S, Nesterets YI, Gureyev TE, Mayo SC, Pogany A, Stevenson AW. On the evolution and relative merits of hard X-ray phase-contrast imaging methods. Philos Trans A Math Phys Eng Sci 2014 ;372(2010):20130021. https://doi.org/10.1098/rsta.2013.0021 .
pubmed: 24470408
Endrizzi M. X-ray phase-contrast imaging. Nucl Instrum Methods Phys Res A 2018;878:88–98. https://doi.org/10.1016/j.nima.2017.07.036 .
Zdora MC. State of the art of X-ray speckle-based phase-contrast and dark-field imaging. J Imaging 2018;4(60):2018. https://doi.org/10.3390/jimaging4050060 .
Bonse U, Hart M. An X-ray interferometer with long interfering beam paths. Appl Phys Lett 1965;7:99–101. https://doi.org/10.1063/1.1754330 .
Momose A, Takeda T, Itai Y, Hirano K. Phase-contrast X-ray computed tomography for observing biological soft tissues. Nat Med 1996;2(4):473–5. https://doi.org/10.1038/nm0496-473 .
pubmed: 8597962
Snigirev A, Snigireva I, Kohn V, Kuznetsov S, Schelokov I. On the possibilities of X-ray phase contrast microimaging by coherent high-energy synchrotron radiation. Rev Sci Instrum 1995;66:5486. https://doi.org/10.1063/1.1146073 .
Nugent KA, Gureyev TE, Cookson DJ, Paganin D, Barnea Z. Quantitative phase imaging using hard X rays. Phys Rev Lett 1996;77(14):2961–2964. https://doi.org/10.1103/PhysRevLett.77.2961 .
pubmed: 10062096
Cloetens P, Barrett R, Baruchel J, Guigay JP, Schlenker M. Phase objects in synchrotron radiation hard x-ray imaging. J Phys D Appl Phys 1996;29:133. https://doi.org/10.1088/0022-3727/29/1/023 .
Wilkins S, Gureyev T, Gao D, Pogany A, Stevenson AW. Phase-contrast imaging using polychromatic hard X-rays. Nature 1996;384:335–338. https://doi.org/10.1038/384335a0 .
Paganin D, Nugent KA. Noninterferometric phase imaging with partially coherent light. Phys Rev Lett 1998;80:2586. https://doi.org/10.1103/PhysRevLett.80.2586 .
Davis TJ, Gao D, Gureyev TE, Stevenson AW, Wilkins S. 1995. Phase-contrast of weakly absorbing materials using hard X-rays. Nature 373595–8. https://doi.org/10.1038/373595a0 .
Chapman D, Thomlinson W, Johnston RE, Washburn D, Pisano E, Gmür N, Zhong Z, Menk R, Arfelli F, Sayers D. Diffraction enhanced x-ray imaging. Phys Med Biol 1997;42(11):2015–25. https://doi.org/10.1088/0031-9155/42/11/001 .
pubmed: 9394394
Gureyev TE, Wilkins S. Regimes of X-ray phase-contrast imaging with perfect crystals. Nouv Cim D 1997;19:545–552. https://doi.org/10.1007/BF03041015 .
Mayo S, Davis T, Gureyev T, Miller P, Paganin D, Pogany A, Stevenson A, Wilkins S. X-ray phase-contrast microscopy and microtomography. Opt Express 2003;11(19):2289–302. https://doi.org/10.1364/oe.11.002289 .
pubmed: 19471337
Nesterets YI, Gureyev TE, Paganin D, Pavlov KM, Wilkins S. Quantitative diffraction-enhanced x-ray imaging of weak objects. J Phys D, Appl Phys 2004;37:1262–1274. https://doi.org/10.1088/0022-3727/37/8/016 .
David C, Nöhammer B, Solak H, Ziegler E. Differential X-ray phase contrast imaging using a shearing interferometer. Appl Phys Lett 2002;81:3287–3289. https://doi.org/10.1063/1.1516611 .
Momose A. Phase-sensitive imaging and phase tomography using X-ray interferometers. Opt Express 2003;11(19):2303–14. https://doi.org/10.1364/oe.11.002303 .
pubmed: 19471338
Weitkamp T, Diaz A, David C, Pfeiffer F, Stampanoni M, Cloetens P, Ziegler E. X-ray phase imaging with a grating interferometer. Opt Express 2005;13(16):6296–304. https://doi.org/10.1364/opex.13.006296 .
pubmed: 19498642
Momose A, Yashiro W, Maikusa H, Takeda Y. High-speed X-ray phase imaging and X-ray phase tomography with Talbot interferometer and white synchrotron radiation. Opt Express 2009;17 (15):12540–5. https://doi.org/10.1364/oe.17.012540 .
pubmed: 19654656
Pfeiffer F, Weitkamp T, Bunk O, David C. Phase retrieval and differential phase-contrast imaging with low brilliance X-ray sources. Nat Phys 2006;2:258–261.
Olivo A, Arfelli F, Cantatore G, Longo R, Menk RH, Pani S, Prest M, Poropat P, Rigon L, Tromba G, Vallazza E, Castelli E. An innovative digital imaging set-up allowing a low-dose approach to phase contrast applications in the medical field. Med Phys 2001;28(8):1610–9. https://doi.org/10.1118/1.1388219 .
pubmed: 11548930
Olivo A, Speller R. Modelling of a novel x-ray phase contrast imaging technique based on coded apertures. Phys Med Biol 2007;52(22):6555–73. https://doi.org/10.1088/0031-9155/52/22/001 .
pubmed: 17975283
Munro PR, Ignatyev K, Speller R, Olivo A. Source size and temporal coherence requirements of coded aperture type x-ray phase contrast imaging systems. Opt Express 2010;18(19):19681–92. https://doi.org/10.1364/OE.18.019681 .
pubmed: 20940863
Endrizzi M, Vittoria FA, Kallon G, Basta D, Diemoz PC, Vincenzi A, Delogu P, Bellazzini R, Olivo A. Achromatic approach to phase-based multi-modal imaging with conventional X-ray sources. Opt Express 2015;23(12):16473–80. https://doi.org/10.1364/OE.23.016473 .
pubmed: 26193618
Cerbino R, Peverini L, Potenza M, et al. X-ray-scattering information obtained from near-field speckle. Nature Phy 2008;4:238–243. https://doi.org/10.1038/nphys837 .
Morgan KS, Paganin DM, Siu KK. Quantitative single-exposure x-ray phase contrast imaging using a single attenuation grid. Opt Express 2011;19(20):19781–9. https://doi.org/10.1364/OE.19.019781 .
pubmed: 21996920
Morgan KS, Paganin DM, Siu KK. Quantitative x-ray phase-contrast imaging using a single grating of comparable pitch to sample feature size. Opt Lett 2011;36(1):55–7. https://doi.org/10.1364/OL.36.000055 .
pubmed: 21209685
Zanette I, Zhou T, Burvall A, Lundström U, Larsson DH, Zdora M, Thibault P, Pfeiffer F, Hertz HM. Speckle-based x-ray phase-contrast and dark-field imaging with a laboratory source. Phys Rev Lett 2014;112(25):253903. https://doi.org/10.1103/PhysRevLett.112.253903 .
pubmed: 25014818
Pogany A, Gao D, Wilkins S. Contrast and resolution in imaging with a microfocus x-ray source. Rev Sci Instr 1997;68(7):2774–2782. https://doi.org/10.1063/1.1148194 .
Pfeiffer F, Kottler C, Bunk O, David C. Hard x-ray phase tomography with low-brilliance sources. Phys Rev Lett 2007;98(10):108105. https://doi.org/10.1103/PhysRevLett.98.108105 .
pubmed: 17358572
Töpperwien M, van der Meer F, Stadelmann C, Salditt T. Three-dimensional virtual histology of human cerebellum by X-ray phase-contrast tomography. Proc Natl Acad Sci USA 2018;115(27):6940–6945. https://doi.org/10.1073/pnas.1801678115 .
pubmed: 29915047
pmcid: 6142271
Krenkel M, Töpperwien M, Dullin C, Alves F, Salditt T. Propagation-based phase-contrast tomographyfor high-resolution lung imaging with laboratory sources. AIP Adv 2016;035007:6. https://doi.org/10.1063/1.4943898 .
Hagen CK, Maghsoudlou P, Totonelli G, Diemoz PC, Endrizzi M, Rigon L, Menk RH, Arfelli F, Dreossi D, Brun E, Coan P, Bravin A, De Coppi P, Olivo A. High contrast microstructural visualization of natural acellular matrices by means of phase-based x-ray tomography. Sci Rep 2015;5:18156. https://doi.org/10.1038/srep18156 .
pubmed: 26657471
pmcid: 4677348
Hellerhoff K, Birnbacher L, Sztrókay-Gaul A, Grandl S, Auweter S, Willner M, Marschner M, Mayr D, Reiser MF, Pfeiffer F, Herzen J. Assessment of intraductal carcinoma in situ (DCIS) using grating-based X-ray phase-contrast CT at conventional X-ray sources: an experimental ex-vivo study. PLoS One 2019;14(1):e0210291. https://doi.org/10.1371/journal.pone.0210291 .
pubmed: 30625220
pmcid: 6326478
Sardanelli F. Trends in radiology and experimental research. Eur Radiol Exp 2017;1 (1):1. https://doi.org/10.1186/s41747-017-0006-5 .
pubmed: 29708170
pmcid: 5909338
Alvarez RE, Macovski A. Energy-selective reconstructions in X-ray computerized tomography. Phys Med Biol 1976;21(5):733–44. https://doi.org/10.1088/0031-9155/21/5/002 .
pubmed: 967922
Kalender WA, Perman WH, Vetter JR, Klotz E. Evaluation of a prototype dual-energy computed tomographic apparatus. I. Phantom studies. Med Phys 1986;13(3):334–9. https://doi.org/10.1118/1.595958 .
pubmed: 3724693
Torikoshi M, Tsunoo T, Sasaki M, Endo M, Noda Y, Ohno Y, Kohno T, Hyodo K, Uesugi K, Yagi N. Electron density measurement with dual-energy x-ray CT using synchrotron radiation. Phys Med Biol 2003;48(5):673–85. https://doi.org/10.1088/0031-9155/48/5/308 .
pubmed: 12696802
Schlomka JP, Roessl E, Dorscheid R, Dill S, Martens G, Istel T, Bäumer C, Herrmann C, Steadman R, Zeitler G, Livne A, Proksa R. Experimental feasibility of multi-energy photon-counting K-edge imaging in pre-clinical computed tomography. Phys Med Biol 2008;53(15): 4031–47. https://doi.org/10.1088/0031-9155/53/15/002 .
pubmed: 18612175
McCollough CH, Leng S, Yu L, Fletcher JG. Dual- and multi-energy CT: principles, technical approaches, and clinical applications. Radiology 2015;276(3):637–53. https://doi.org/10.1148/radiol.2015142631 .
pubmed: 26302388
van Abbema JK, van Goethem MJ, Greuter MJ, van der Schaaf A, Brandenburg S, van der Graaf ER. Relative electron density determination using a physics based parameterization of photon interactions in medical DECT. Phys Med Biol 2015;60(9):3825–46. https://doi.org/10.1088/0031-9155/60/9/3825 .
pubmed: 25905890
Lee SH, Hur J, Kim YJ, Lee HJ, Hong YJ, Choi BW. Additional value of dual-energy CT to differentiate between benign and malignant mediastinal tumors: an initial experience. Eur J Radiol 2013;82(11):2043–9. https://doi.org/10.1016/j.ejrad.2013.05.040 .
pubmed: 23820175
Mileto A, Marin D, Alfaro-Cordoba M, Ramirez-Giraldo JC, Eusemann CD, Scribano E, Blandino A, Mazziotti S, Ascenti G. Iodine quantification to distinguish clear cell from papillary renal cell carcinoma at dual-energy multidetector CT: a multireader diagnostic performance study. Radiology. 2014;273(3): 813–20. https://doi.org/10.1148/radiol.14140171 .
pubmed: 25162309
Kaltenbach B, Wichmann JL, Pfeifer S, Albrecht MH, Booz C, Lenga L, Hammerstingl R, D’Angelo T, Vogl TJ, Martin SS. Iodine quantification to distinguish hepatic neuroendocrine tumor metastasis from hepatocellular carcinoma at dual-source dual-energy liver CT. Eur J Radiol 2018;105: 20–24. https://doi.org/10.1016/j.ejrad.2018.05.019 .
pubmed: 30017280
Boll DT, Patil NA, Paulson EK, Merkle EM, Simmons WN, Pierre SA, Preminger GM. Renal stone assessment with dual-energy multidetector CT and advanced postprocessing techniques: improved characterization of renal stone composition–pilot study. Radiology 2009;250(3): 813–20. https://doi.org/10.1148/radiol.2503080545 .
pubmed: 19244048
Leng S, Huang A, Cardona JM, Duan X, Williams JC, McCollough CH. Dual-energy CT for quantification of urinary stone composition in mixed stones: a phantom study. AJR Am J Roentgenol 2016;207(2):321–9. https://doi.org/10.2214/AJR.15.15692 .
pubmed: 27224260
pmcid: 5010238
Tijssen MP, Hofman PA, Stadler AA, van Zwam W, de Graaf R, van Oostenbrugge RJ, Klotz E, Wildberger JE, Postma AA. The role of dual energy CT in differentiating between brain haemorrhage and contrast medium after mechanical revascularisation in acute ischaemic stroke. Eur Radiol 2014;24 (4):834–40. https://doi.org/10.1007/s00330-013-3073-x .
pubmed: 24258277
Zhou T, Lundström U, Thüring T, Rutishauser S, Larsson DH, Stampanoni M, David C, Hertz HM, Burvall A. Comparison of two x-ray phase-contrast imaging methods with a microfocus source. Opt Express 2013;21(25):30183–95. https://doi.org/10.1364/OE.21.030183 .
pubmed: 24514597
Birnbacher L, Willner M, Velroyen A, Marschner M, Hipp A, Meiser J, Koch F, Schröter T, Kunka D, Mohr J, Pfeiffer F, Herzen J. Experimental realisation of high-sensitivity laboratory x-ray grating-based phase-contrast computed tomography. Sci Rep 2016;6: 24022. https://doi.org/10.1038/srep24022 .
pubmed: 27040492
pmcid: 4819174
Willner M, Herzen J, Grandl S, Auweter S, Mayr D, Hipp A, Chabior M, Sarapata A, Achterhold K, Zanette I, Weitkamp T, Sztrókay A, Hellerhoff K, Reiser M, Pfeiffer F. Quantitative breast tissue characterization using grating-based x-ray phase-contrast imaging. Phys Med Biol 2014;59(7):1557–71. https://doi.org/10.1088/0031-9155/59/7/1557 .
pubmed: 24614413
Bech M, Jensen TH, Feidenhans’l R, Bunk O, David C, Pfeiffer F. Soft-tissue phase-contrast tomography with an x-ray tube source. Phys Med Biol 2009;54(9):2747–53. https://doi.org/10.1088/0031-9155/54/9/010 .
pubmed: 19369710
Herzen J, Donath T, Pfeiffer F, Bunk O, Padeste C, Beckmann F, Schreyer A, David C. Quantitative phase-contrast tomography of a liquid phantom using a conventional x-ray tube source. Opt Express 2009;17(12):10010–8. https://doi.org/10.1364/oe.17.010010 .
pubmed: 19506651
Woodard HQ, White DR. The composition of body tissues. Br J Radiol 1986;59(708):1209–1218. https://doi.org/10.1259/0007-1285-59-708-1209 .
pubmed: 3801800
Notohamiprodjo S, Webber N, Birnbacher L, Willner M, Viermetz M, Herzen J, Marschner M, Mayr D, Bartsch H, Saam T, Auweter S, Pfeiffer F, Reiser MF, Hetterich H. Qualitative and quantitative evaluation of structural myocardial alterations by grating-based phase-contrast computed tomography. Invest Radiol 2018;53(1):26–34. https://doi.org/10.1097/RLI.0000000000000408 .
pubmed: 28846552
Hetterich H, Willner M, Habbel C, Herzen J, Hoffmann VS, Fill S, Hipp A, Marschner M, Schüller U, Auweter S, Massberg S, Reiser MF, Pfeiffer F, Saam T, Bamberg F. X-ray phase-contrast computed tomography of human coronary arteries. Invest Radiol 2015;50(10): 686–94. https://doi.org/10.1097/RLI.0000000000000169 .
pubmed: 26002622
Braunagel M, Birnbacher L, Willner M, Marschner M, De Marco F, Viermetz M, Notohamiprodjo S, Hellbach K, Auweter S, Link V, Woischke C, Reiser MF, Pfeiffer F, Notohamiprodjo M, Herzen J. Qualitative and quantitative imaging evaluation of renal cell carcinoma subtypes with grating-based x-ray phase-contrast CT. Sci Rep 2017;7:45400. https://doi.org/10.1038/srep45400 .
pubmed: 28361951
pmcid: 5374440
Fingerle AA, Willner M, Herzen J, Münzel D, Hahn D, Rummeny EJ, Noël PB, Pfeiffer F. Simulated cystic renal lesions: quantitative X-ray phase-contrast CT–an in vitro phantom study. Radiology 2014;272(3):739–48. https://doi.org/10.1148/radiol.14130876 .
pubmed: 24814175
Tapfer A, Braren R, Bech M, Willner M, Zanette I, Weitkamp T, Trajkovic-Arsic M, Siveke JT, Settles M, Aichler M, Walch A, Pfeiffer F. X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model. PLoS One 2013;8(3):e58439. https://doi.org/10.1371/journal.pone.0058439 .
pubmed: 23536795
pmcid: 3594292
Richter V, Willner MS, Henningsen J, Birnbacher L, Marschner M, Herzen J, Kimm MA, Noël PB, Rummeny EJ, Pfeiffer F, Fingerle AA. Ex vivo characterization of pathologic fluids with quantitative phase-contrast computed tomography. Eur J Radiol 2017;86:99–104. https://doi.org/10.1016/j.ejrad.2016.11.014
pubmed: 28027773
Pfeiffer F, Bunk O, David C, Bech M, Le Duc G, Bravin A, Cloetens P. High-resolution brain tumor visualization using three-dimensional x-ray phase contrast tomography. Phys Med Biol 2007;52(23):6923–30. https://doi.org/10.1088/0031-9155/52/23/010 .
pubmed: 18029984
Schulz G, Weitkamp T, Zanette I, Pfeiffer F, Beckmann F, David C, Rutishauser S, Reznikova E, Müller B. High-resolution tomographic imaging of a human cerebellum: comparison of absorption and grating-based phase contrast. J R Soc Interface 2010;7(53): 1665–76. https://doi.org/10.1098/rsif.2010.0281 .
pubmed: 20659930
pmcid: 2988270
Schulz G, Waschkies C, Pfeiffer F, Zanette I, Weitkamp T, David C, Müller B. Multimodal imaging of human cerebellum - merging X-ray phase microtomography, magnetic resonance microscopy and histology. Sci Rep 2012;2:826. https://doi.org/10.1038/srep00826 .
pubmed: 23145319
pmcid: 3494013
Zanette I, Weitkamp T, Le Duc G, Pfeiffer F. X-ray grating-based phase tomography for 3D histology. RSC Adv 2013;3(43):19816. https://doi.org/10.1039/C3RA41372A .
Thalmann P, Bikis C, Hipp A, Müller B, Hieber SE, Schulz G. Single and double grating-based X-ray microtomography using synchrotron radiation. Single Appl Phys Lett 2017;110: 061103. https://doi.org/10.1063/1.4975679 .
Sztrókay A, Herzen J, Auweter SD, Liebhardt S, Mayr D, Willner M, Hahn D, Zanette I, Weitkamp T, Hellerhoff K, Pfeiffer F, Reiser MF, Bamberg F. Assessment of grating-based X-ray phase-contrast CT for differentiation of invasive ductal carcinoma and ductal carcinoma in situ in an experimental ex vivo set-up. Eur Radiol 2013;23(2):381–7. https://doi.org/10.1007/s00330-012-2592-1 .
pubmed: 22932738
Grandl S, Willner M, Herzen J, Sztrókay-Gaul A, Mayr D, Auweter SD, Hipp A, Birnbacher L, Marschner M, Chabior M, Reiser M, Pfeiffer F, Bamberg F, Hellerhoff K. Visualizing typical features of breast fibroadenomas using phase-contrast CT: an ex-vivo study. PLoS One 2014;9(5):e97101. https://doi.org/10.1371/journal.pone.0097101 .
pubmed: 24824169
pmcid: 4019647
Willner M, Fior G, Marschner M, Birnbacher L, Schock J, Braun C, Fingerle AA, Noël PB, Rummeny EJ, Pfeiffer F, Herzen J. 2015. Phase-contrast Hounsfield units of fixated and non-fixated soft-tissue samples, Vol. 10. https://doi.org/10.1371/journal.pone.0137016 .
Donath T, Pfeiffer F, Bunk O, Grünzweig C, Hempel E, Popescu S, Vock P, David C. Toward clinical X-ray phase-contrast CT: demonstration of enhanced soft-tissue contrast in human specimen. Invest Radiol 2010;45(7):445–52. https://doi.org/10.1097/RLI.0b013e3181e21866 .
pubmed: 20498610
Qi Z, Zambelli J, Bevins N, Chen GH. Quantitative imaging of electron density and effective atomic number using phase contrast CT. Phys Med Biol 2010;55(9):2669–77. https://doi.org/10.1088/0031-9155/55/9/016 .
pubmed: 20400806
pmcid: 3746746
Willner M, Bech M, Herzen J, Zanette I, Hahn D, Kenntner J, Mohr J, Rack A, Weitkamp T, Pfeiffer F. Quantitative X-ray phase-contrast computed tomography at 82 keV. Opt Express 2013;21(4):4155–66. https://doi.org/10.1364/OE.21.004155 .
pubmed: 23481949
Birnbacher L, Willner M, Marschner M, Pfeiffer D, Pfeiffer F, Herzen J. Accurate effective atomic number determination with polychromatic grating-based phase-contrast computed tomography. Opt Express 2018;26(12):15153–15166. https://doi.org/10.1364/OE.26.015153 .
pubmed: 30114766
Willner M, Viermetz M, Marschner M, Scherer K, Braun C, Fingerle A, Noël P, Rummeny E, Pfeiffer F, Herzen J. Quantitative three-dimensional imaging of lipid, protein, and water contents via X-ray phase-contrast tomography. PLoS One 2016;11(3):e0151889. https://doi.org/10.1371/journal.pone.0151889 .
pubmed: 27003308
pmcid: 4803315
Braig E, Böhm J, Dierolf M, Jud C, Günther B, Mechlem K, Allner S, Sellerer T, Achterhold K, Gleich B, Noël P, Pfeiffer D, Rummeny E, Herzen J, Pfeiffer F. Direct quantitative material decomposition employing grating-based X-ray phase-contrast CT. Sci Rep 2018;8 (1):16394. https://doi.org/10.1038/s41598-018-34809-6 .
pubmed: 30401876
pmcid: 6219573
Braig EM, Pfeiffer D, Willner M, Sellerer T, Taphorn K, Petrich C, Scholz J, Petzold L, Birnbacher L, Dierolf M, Pfeiffer F, Herzen J. Single spectrum three-material decomposition with grating-based x-ray phase-contrast CT. Phys Med Biol 2020;65(18):185011. https://doi.org/10.1088/1361-6560/ab9704 .
pubmed: 32460250
Ji X, Zhang R, Li K, Chen GH. Dual energy differential phase contrast CT (DE-DPC-CT) imaging. IEEE Trans Med Imaging 2020;39(11):3278–3289. https://doi.org/10.1109/TMI.2020.2990347 .
pubmed: 32340940
pmcid: 7584735
Cloetens P, Guigay JP, De Martino C, Baruchel J, Schlenker M. Fractional Talbot imaging of phase gratings with hard x rays. Opt Lett 1997;22(14):1059–61. https://doi.org/10.1364/ol.22.001059 .
pubmed: 18185750
Paganin DM. Coherent X-ray optics. Oxford: Oxford University; 2009. 424 pp.
Yashiro W. Hard X-ray imaging microscopy with self-imaging phenomenon. Microscopy (Oxf) 2018;67(6):303–316. https://doi.org/10.1093/jmicro/dfy040 .
Pfeiffer F, Bunk O, Schulze-Briese C, Diaz A, Weitkamp T, David C, van der Veen JF, Vartanyants I, Robinson IK. Shearing interferometer for quantifying the coherence of hard x-ray beams. Phys Rev Lett 2005;94(16):164801. https://doi.org/10.1103/PhysRevLett.94.164801 .
pubmed: 15904233
Pfeiffer F, Bech M, Bunk O, Kraft P, Eikenberry EF, Brönnimann Ch, Grünzweig C, David C. Hard-X-ray dark-field imaging using a grating interferometer. Nat Mater 2008;7(2):134–7. https://doi.org/10.1038/nmat2096 .
pubmed: 18204454
Bevins N, Zambelli J, Li K, Qi Z, Chen GH. Multicontrast x-ray computed tomography imaging using Talbot-Lau interferometry without phase stepping. Med Phys 2012;39(1): 424–8. https://doi.org/10.1118/1.3672163 .
pubmed: 22225312
Wen HH, Bennett EE, Kopace R, Stein AF, Pai V. Single-shot x-ray differential phase-contrast and diffraction imaging using two-dimensional transmission gratings. Opt Lett 2010;35(12):1932–4. https://doi.org/10.1364/OL.35.001932 .
pubmed: 20548343
pmcid: 3091831
Wen HH, Miao H, Bennett EE, Adamo NM, Chen L. Flexible retrospective phase stepping in x-ray scatter correction and phase contrast imaging using structured illumination. PLoS One 2013;8(10):e78276. https://doi.org/10.1371/journal.pone.0078276 .
pubmed: 24205177
pmcid: 3814970
Pelzer G, Rieger J, Hauke C, Horn F, Michel T, Seifert M, Anton G. Reconstruction method for grating-based x-ray phase-contrast images without knowledge of the grating positions. J Instrum 2015;10(12):P12017. https://doi.org/10.1088/1748-0221/10/12/P12017 .
Seifert M, Kaeppler S, Hauke C, Horn F, Pelzer G, Rieger J, Michel T, Riess C, Anton G. Optimisation of image reconstruction for phase-contrast x-ray Talbot-Lau imaging with regard to mechanical robustness. Phys Med Biol 2016;61(17):6441–64. https://doi.org/10.1088/0031-9155/61/17/6441 .
pubmed: 27514576
Kaeppler S, Rieger J, Pelzer G, Horn F, Michel T, Maier A, Anton G, Riess C. Improved reconstruction of phase-stepping data for Talbot-Lau x-ray imaging. J Med Imaging (Bellingham) 2017;4(3):034005. https://doi.org/10.1117/1.JMI.4.3.034005 .
De Marco F, Marschner M, Birnbacher L, Noël P, Herzen J, Pfeiffer F. Analysis and correction of bias induced by phase stepping jitter in grating-based X-ray phase-contrast imaging. Opt Express 2018;26(10):12707–12722. https://doi.org/10.1364/OE.26.012707 .
pubmed: 29801307
Tapfer A, Bech M, Velroyen A, Meiser J, Mohr J, Walter M, Schulz J, Pauwels B, Bruyndonckx P, Liu X, Sasov A, Pfeiffer F. Experimental results from a preclinical X-ray phase-contrast CT scanner. Proc Natl Acad Sci USA 2012;109(39):15691–6. https://doi.org/10.1073/pnas.1207503109 .
pubmed: 23019354
pmcid: 3465429
Epple FM, Potdevin G, Thibault P, Ehn S, Herzen J, Hipp A, Beckmann F, Pfeiffer F. Unwrapping differential x-ray phase-contrast images through phase estimation from multiple energy data. Opt Express 2013;21(24):29101–8. https://doi.org/10.1364/OE.21.029101 .
pubmed: 24514461
Epple FM, Ehn S, Thibault P, Koehler T, Potdevin G, Herzen J, Pennicard D, Graafsma H, Noël PB, Pfeiffer F. Phase unwrapping in spectral X-ray differential phase-contrast imaging with an energy-resolving photon-counting pixel detector. IEEE Trans Med Imaging 2015;34(3):816–23. https://doi.org/10.1109/TMI.2014.2349852 .
pubmed: 25163054
Raupach R, Flohr TG. Analytical evaluation of the signal and noise propagation in x-ray differential phase-contrast computed tomography. Phys Med Biol 2011;56(7):2219–44. https://doi.org/10.1088/0031-9155/56/7/020 .
pubmed: 21403187
Köhler T, Brendel B, Roessl E. Iterative reconstruction for differential phase contrast imaging using spherically symmetric basis functions. Med Phys 2011;38(8):4542–5. https://doi.org/10.1118/1.3608906 .
pubmed: 21928625
Chen GH, Zambelli J, Li K, Bevins N, Qi Z. Scaling law for noise variance and spatial resolution in differential phase contrast computed tomography. Med Phys 2011;38(2):584–8. https://doi.org/10.1118/1.3533718 .
pubmed: 21452695
pmcid: 3030613
Weber T, Pelzer G, Rieger J, Ritter A, Anton G. Report of improved performance in Talbot-Lau phase-contrast computed tomography. Med Phys 2015;42(6):2892–6. https://doi.org/10.1118/1.4921022 .
pubmed: 26127042
Zhu P, Zhang K, Wang Z, Liu Y, Liu X, Wu Z, McDonald SA, Marone F, Stampanoni M. Low-dose, simple, and fast grating-based X-ray phase-contrast imaging. Proc Natl Acad Sci USA 2010;107(31):13576–81. https://doi.org/10.1073/pnas.1003198107 .
pubmed: 20643971
pmcid: 2922255
Wu Z, Gao K, Wang Z, Ge X, Chen J, Wang D, Pan Z, Zhang K, Zhu P, Wu Z. A new method to retrieve phase information for equiangular fan beam differential phase contrast computed tomography. Med Phys 2013;40(3):031911. https://doi.org/10.1118/1.4791672 .
pubmed: 23464326
Marschner M, Birnbacher L, Willner M, Chabior M, Herzen J, Noël PB, Pfeiffer F. Revising the lower statistical limit of x-ray grating-based phase-contrast computed tomography. PLoS One 2017;12 (9):e0184217. https://doi.org/10.1371/journal.pone.0184217 .
pubmed: 28877253
pmcid: 5587302
Zanette I, Bech M, Rack A, Le Duc G, Tafforeau P, David C, Mohr J, Pfeiffer F, Weitkamp T. Trimodal low-dose X-ray tomography. Proc Natl Acad Sci USA 2012;109(26):10199–204. https://doi.org/10.1073/pnas.1117861109 .
pubmed: 22699500
pmcid: 3387041
Xu Q, Sidky EY, Pan X, Stampanoni M, Modregger P, Anastasio MA. Investigation of discrete imaging models and iterative image reconstruction in differential X-ray phase-contrast tomography. Opt Express 2012;20(10):10724–49. https://doi.org/10.1364/OE.20.010724 .
pubmed: 22565698
pmcid: 3482908
Nilchian M, Vonesch C, Modregger P, Stampanoni M, Unser M. Fast iterative reconstruction of differential phase contrast X-ray tomograms. Opt Express 2013;21(5):5511–28. https://doi.org/10.1364/OE.21.005511 .
pubmed: 23482123
Hahn D, Thibault P, Fehringer A, Bech M, Koehler T, Pfeiffer F, Noël PB. Statistical iterative reconstruction algorithm for X-ray phase-contrast CT. Sci Rep 2015;5:10452. https://doi.org/10.1038/srep10452 .
pubmed: 26067714
pmcid: 4464273
Burger K, Koehler T, Chabior M, Allner S, Marschner M, Fehringer A, Willner M, Pfeiffer F, Noël P. Regularized iterative integration combined with non-linear diffusion filtering for phase-contrast x-ray computed tomography. Opt Express 2014;22(26):32107–18. https://doi.org/10.1364/OE.22.032107 .
pubmed: 25607176
Brendel B, von Teuffenbach M, Noël PB, Pfeiffer F, Koehler T. Penalized maximum likelihood reconstruction for x-ray differential phase-contrast tomography. Med Phys 2016;43(1):188. https://doi.org/10.1118/1.4938067 .
pubmed: 26745911
Teuffenbach MV, Koehler T, Fehringer A, Viermetz M, Brendel B, Herzen J, Proksa R, Rummeny EJ, Pfeiffer F, Noël PB. Grating-based phase-contrast and dark-field computed tomography: a single-shot method. Sci Rep 2017;7(1):7476. https://doi.org/10.1038/s41598-017-06729-4 .
pubmed: 28785015
pmcid: 5547164
Allner S, Koehler T, Fehringer A, Birnbacher L, Willner M, Pfeiffer F, Noël PB. Bilateral filtering using the full noise covariance matrix applied to x-ray phase-contrast computed tomography. Phys Med Biol 2016;61(10):3867–56. https://doi.org/10.1088/0031-9155/61/10/3867 .
pubmed: 27100408
Thuering T, Zhou T, Lundström U, Burvall A, Rutishauser S, David C, Hertz H, Stampanoni M. X-ray grating interferometry with a liquid-metal-jet source. Appl Phys Lett 2013;091105:103. https://doi.org/10.1063/1.4819766 .
Khimchenko A, Schulz G, Thalmann P, Müller B. Implementation of a double-grating interferometer for phase-contrast computed tomography in a conventional system nanotom(R) m. APL Bioeng 2018;2 (1):016106. https://doi.org/10.1063/1.5022184 .
pubmed: 31069291
pmcid: 6481705
Momose A, Yashiro W, Kuwabara H, Kawabata K. Grating-based X-ray phase imaging using multiline X-ray source. Jap J Appl Phys 2009;48(7):076512. https://doi.org/10.1143/jjap.48.076512 .
Guo J, Xin L, Zhou B, Du Y, Lei Y, Niu H. Development of key devices of grating-based X-ray phase-contrast imaging technology at Shenzhen University. AIP Conf Proc 2012 2012;1466:61–66. https://doi.org/10.1063/1.4742270 .
Engelhardt M, Kottler C, Bunk O, David C, Schroer C, Baumann J, Schuster M, Pfeiffer F. The fractional Talbot effect in differential x-ray phase-contrast imaging for extended and polychromatic x-ray sources. J Microsc 2008;232(1):145–57. https://doi.org/10.1111/j.1365-2818.2008.02072.x .
pubmed: 19017212
Chabior M, Donath T, David C, Bunk O, Schuster M, Schroer C, Pfeiffer F. Beam hardening effects in grating-based x-ray phase-contrast imaging. Med Phys 2011;38(3):1189–95. https://doi.org/10.1118/1.3553408 .
pubmed: 21520831
Hipp A, Willner M, Herzen J, Auweter S, Chabior M, Meiser J, Achterhold K, Mohr J, Pfeiffer F. Energy-resolved visibility analysis of grating interferometers operated at polychromatic X-ray sources. Opt Express 2014;22(25):30394–409. https://doi.org/10.1364/OE.22.030394 .
pubmed: 25606986
Taylor ML, Smith RL, Franich RD. Robust calculation of effective atomic numbers: the Auto-Zeff software. Med Phys 2012;39(4):2473–4209. https://doi.org/10.1118/1.3689810 .
Murty RC. Effective atomic numbers of heterogeneous materials. Nature 1965;207:398–399. https://doi.org/10.1038/207398a0 .
Spiers W. Effective atomic number and energy absorption in tissues. Br J Radiol 1946;19: 52–63. https://doi.org/10.1259/0007-1285-19-218-52 .
pubmed: 21015391
Hubbell JH. 1969. Photon cross sections, attenuation coefficients, and energy absorption coefficients from 10 keV to 100 GeV. Natl Stand Ref Data Ser NSRDS 29.
McCullough EC. Photon attenuation in computed tomography. Med Phys 1975;2(6):307–20. https://doi.org/10.1118/1.594199 .
pubmed: 1105130
Saloman EB, Hubbell JH. 1986. X-ray attenuation coefficients (total cross sections): comparison of the experimental data base with recommended values of Henke and the theoretical values of Scofield for energies between 0.1-100 keV. National Bureau of Standards Report NBSIR. 86-3431.
Saloman EB, Hubbell JH, Scofield JH. 1988. X-ray attenuation cross sections for energies 100 eV to 100 keV and elements Z = 1 to Z = 92 atomic data and Nucl. Data Tables 38(1).
Berger MJ, Hubbell JH, Seltzer SM, Chang J, Coursey JS, Sukumar R, Zucker DS, Olsen K. 2010. XCOM: photon cross section database. National Bureau of Standards Report NBSIR. https://doi.org/10.18434/T48G6X .
Engelhardt M, Baumann J, Schuster M, Kottler C, Pfeiffer F, Bunk O, David C. 2007. High-resolution differential phase contrast imaging using a magnifying projection geometry with a microfocus x-ray source. Appl Phys Lett 90. https://doi.org/10.1063/1.2743928 .
Yashiro W, Takeda Y, Momose A. Efficiency of capturing a phase image using cone-beam x-ray Talbot interferometry. J Opt Soc Am A Opt Image Sci Vis 2008;25(8):2025–39. https://doi.org/10.1364/josaa.25.002025 .
pubmed: 18677365
Modregger P, Pinzer BR, Thüring T, Rutishauser S, David C, Stampanoni M. Sensitivity of X-ray grating interferometry. Opt Express 2011;19(19):18324–38. https://doi.org/10.1364/OE.19.018324 .
pubmed: 21935201
Chabior M, Schuster M, Schroer C, Pfeiffer F. Grating-based phase-contrast computed tomography of thick samples. Nucl Instrum Methods Phys Res 2012;693:138–142. https://doi.org/10.1016/j.nima.2012.07.041 .
Donath T, Pfeiffer F, Bunk O, Groot W, Bednarzik M, Grünzweig C, Hempel E, Popescu S, Hoheisel M, David C. Phase-contrast imaging and tomography at 60 keV using a conventional x-ray tube source. Rev Sci Instrum 2009;80(5):053701. https://doi.org/10.1063/1.3127712 .
pubmed: 19485510
Thuering T, Stampanoni M. Performance and optimization of X-ray grating interferometry. Philos Trans A Math Phys Eng Sci 2014;372(2010):20130027. https://doi.org/10.1098/rsta.2013.0027 .
pubmed: 24470411
David C, Ziegler E, Nöhammer B. Wet-etched diffractive lenses for hard X-rays. J Synchrotron Radiat 2001;8(3):1054–5. https://doi.org/10.1107/s0909049501002746 .
pubmed: 11486414
David C, Weitkamp T, Pfeiffer F, Diaz A, Bruder J, Rohbeck T, Groso A, Bunk O, Stampanoni M, Cloetens P. Hard X-ray phase imaging and tomography using a grating interferometer. Spectrochimica Acta Part B 2007;62:626–630. https://doi.org/10.1016/j.sab.2007.03.001 .
Matsumoto M, Takiguchi K, Tanaka M, Hunabiki Y, Takeda H, Momose A, Utsumi Y, Hattori T. Fabrication of diffraction grating for X-ray Talbot interferometer. Microsyst Technol 2007;13:543–546. https://doi.org/10.1007/s00542-006-0226-8 .
Noda D, Tanaka M, Shimada K, Yashiro W, Momose A, Hattori T. Fabrication of large area diffraction grating using LIGA process. Microsyst Technol 2008;14:1311–1315. https://doi.org/10.1007/s00542-008-0584-5 .
Mohr J, Grund T, Kunka D, Kenntner J, Leuthold J, Meiser J, Schulz J, Walter M. High aspect ratio gratings for X-ray phase contrast imaging. AIP Conf Proc 2012;1466:41. https://doi.org/10.1063/1.4742267 .
Bech M, Bunk O, David C, Kraft P, Brönnimann C, Eikenberry EF, Pfeiffer F. X-ray imaging with the PILATUS 100k detector. Appl Radiat Isot 2008;66(4):474–8. https://doi.org/10.1016/j.apradiso.2007.10.003 .
pubmed: 18035547
Gkoumas S, Thuering T, Taboada AG, Arne Jensen A, Michael Rissi M, Broennimann C, Zambon P. Dose-independent near-ideal DQE of a 75 mu m pixel GaAs photon counting spectral detector for breast imaging. Proc SPIE Med Imaging 2019;2019: 10948. https://doi.org/10.1117/12.2512235 .
Scholz J, Birnbacher L, Petrich C, Riedel M, Heck L, Gkoumas D, Sellerer T, Achterhold K, Herzen J. Biomedical x-ray imaging with a GaAs photon-counting detector: a comparative study. APL Photonics 2020;5(10):10.1063/5.0020262.
Pelzer G, Weber T, Anton G, Ballabriga R, Bayer F, Campbell M, Gabor T, Haas W, Horn F, Llopart X, Michel N, Mollenbauer U, Rieger J, Ritter A, Ritter I, Sievers P, Wölfel S, Wong WS, Zang A, Michel T. Grating-based x-ray phase-contrast imaging with a multi energy-channel photon-counting pixel detector. Opt Express 2013;21(22):25677–84. https://doi.org/10.1364/OE.21.025677 .
pubmed: 24216793
Mechlem K, Sellerer T, Viermetz M, Herzen J, Pfeiffer F. A theoretical framework for comparing noise characteristics of spectral, differential phase-contrast and spectral differential phase-contrast x-ray imaging. Phys Med Biol 2020;65(6):065010. https://doi.org/10.1088/1361-6560/ab7106 .
pubmed: 31995518
Zanette I, Weitkamp T, Lang S, Langer M, Mohr J, David C, Baruchel J. Quantitative phase and absorption tomography with an X-ray grating interferometer and synchrotron radiation. Phys Stat Solidi A 2011;208(11):2526–2532. https://doi.org/10.1002/pssa.201184276 .
Zanette I, Lang S, Rack A, Dominietto M, Langer M, Pfeiffer F, Weitkamp T, Müller B. Holotomography versus X-ray grating interferometry: a comparative study. Appl Phys Lett 2013;103(24):244105. https://doi.org/10.1063/1.4848595 .
Ruiz-Yaniz M, Zanette I, Sarapata A, Birnbacher L, Marschner M, Chabior M, Olbinado M, Pfeiffer F, Rack A. Hard X-ray phase-contrast tomography of non-homogeneous specimens: grating interferometry versus propagation-based imaging. J Synchrotron Radiat 2016;23(Pt 5): 1202–9. https://doi.org/10.1107/S1600577516009164 .
pubmed: 27577776
Zdora MC, Vila-Comamala J, Schulz G, Khimchenko A, Hipp A, Cook AC, Dilg D, David C, Grünzweig C, Rau C, Thibault P, Zanette I. X-ray phase microtomography with a single grating for high-throughput investigations of biological tissue. Biomed Opt Express 2017;8(2):1257–1270. https://doi.org/10.1364/BOE.8.001257 .
pubmed: 28271016
pmcid: 5330582
Kaneko Y, Shinohara G, Hoshino M, Morishita H, Morita K, Oshima Y, Takahashi M, Yagi N, Okita Y, Tsukube T. Intact imaging of human heart structure using X-ray phase-contrast tomography. Pediatr Cardiol 2017;38 (2):390–393. https://doi.org/10.1007/s00246-016-1527-z .
pubmed: 27900454
McDonald SA, Marone F, Hintermüller C, Mikuljan G, David C, Pfeiffer F, Stampanoni M. Advanced phase-contrast imaging using a grating interferometer. J Synchrotron Radiat 2009;16(Pt 4):562–72. https://doi.org/10.1107/S0909049509017920 .
pubmed: 19535872
Sarapata A, Willner M, Walter M, Duttenhofer T, Kaiser K, Meyer P, Braun C, Fingerle A, Noël PB, Pfeiffer F, Herzen J. Quantitative imaging using high-energy X-ray phase-contrast CT with a 70 kVp polychromatic X-ray spectrum. Opt Express 2015;23(1):523–35. https://doi.org/10.1364/OE.23.000523 .
pubmed: 25835698
Thüring T, Abis M, Wang Z, David C, Stampanoni M. X-ray phase-contrast imaging at 100 keV on a conventional source. Sci Rep 2014;4:5198. https://doi.org/10.1038/srep05198 .
pubmed: 24903579
pmcid: 4047533
Viermetz M, Birnbacher L, Willner M, Achterhold K, Pfeiffer F, Herzen J. High resolution laboratory grating-based X-ray phase-contrast CT. Sci Rep 2018;8(1):15884. https://doi.org/10.1038/s41598-018-33997-5 .
pubmed: 30367132
pmcid: 6203738
Birnbacher L, Viermetz M, Noichl W, Allner S, Fehringer A, Marschner M, von Teuffenbach M, Willner M, Achterhold K, Noël PB, Koehler T, Herzen J, Pfeiffer F. Tilted grating phase-contrast computed tomography using statistical iterative reconstruction. Sci Rep 2018;8 (1):6608. https://doi.org/10.1038/s41598-018-25075-7 .
pubmed: 29700372
pmcid: 5920057
Winklhofer S, Peter S, Tischler V, Morsbach F, von Werdt M, Berens S, Modregger P, Buser L, Moch H, Stampanoni M, Thali M, Alkadhi H, Stolzmann P. Diagnostic accuracy of quantitative and qualitative phase-contrast imaging for the ex Vivo characterization of human coronary atherosclerotic plaques. Radiology. 2015;277(1):64–72. https://doi.org/10.1148/radiol.2015141614 .
pubmed: 25942503
Bonanno G, Coppo S, Modregger P, Pellegrin M, Stuber A, Stampanoni M, Mazzolai L, Stuber M, van Heeswijk RB. Ultra-high-resolution 3D imaging of atherosclerosis in mice with synchrotron differential phase contrast: a proof of concept study. Sci Rep 2015;5:11980. https://doi.org/10.1038/srep11980 .
pubmed: 26165698
pmcid: 4499839
Herzen J, Karampinos DC, Foehr P, Birnbacher L, Viermetz M, Burgkart R, Baum T, Lohoefer F, Wildgruber M, Schilling F, Willner M, Marschner M, Noël PB, Rummeny EJ, Pfeiffer F, Jungmann PM. 2019. 3D grating-based X-ray phase-contrast computed tomography for high-resolution quantitative assessment of cartilage: an experimental feasibility study with 3T MRI, 7T MRI and biomechanical correlation, Vol. 14. https://doi.org/10.1371/journal.pone.0212106 .
Velroyen A, Bech M, Zanette I, Schwarz J, Rack A, Tympner C, Herrler T, Staab-Weijnitz C, Braunagel M, Reiser M, Bamberg F, Pfeiffer F, Notohamiprodjo M. 2014. X-ray phase-contrast tomography of renal ischemia-reperfusion damage, Vol. 9. https://doi.org/10.1371/journal.pone.0109562 .
Günther B, Gradl R, Jud C, Eggl E, Huang J, Kulpe S, Achterhold K, Gleich B, Dierolf M, Pfeiffer F. The versatile X-ray beamline of the Munich Compact Light Source: design, instrumentation and application. J Synchrotron Radiat 2020;27(5):1395–1414. https://doi.org/10.1107/s1600577520008309 .
pubmed: 32876618
pmcid: 7467334
Eggl E, Dierolf M, Achterhold K, Jud C, Günther B, Braig E, Gleich B, Pfeiffer F. The Munich Compact Light Source: initial performance measures. J Synchrotron Radiat 2016;23(Pt 5): 1137–42. https://doi.org/10.1107/S160057751600967X .
pubmed: 27577768
Eggl E, Schleede S, Bech M, Achterhold K, Loewen R, Ruth RD, Pfeiffer F. X-ray phase-contrast tomography with a compact laser-driven synchrotron source. Proc Natl Acad Sci USA 2015;112(18):5567–72. https://doi.org/10.1073/pnas.1500938112 .
pubmed: 25902493
pmcid: 4426454
Birnbacher L, Maurer S, Scheidt K, Herzen J, Pfeiffer F, Fromme T. Electron density of adipose tissues determined by phase-contrast computed tomography provides a measure for mitochondrial density and fat content. Front Physiol 2018;9:707. https://doi.org/10.3389/fphys.2018.00707 .
pubmed: 29962958
pmcid: 6013718
Gradl R, Zanette I, Ruiz-Yaniz M, Dierolf M, Rack A, Zaslansky P, Pfeiffer F. 2016. Mass density measurement of mineralized tissue with grating-based X-ray phase tomography, Vol. 11. https://doi.org/10.1371/journal.pone.0167797 .
Cloetens P, Ludwig W, Baruchel J, Van Dyck D, Van Landuyt J, Guigay JP, Schlenker M. Holotomography: quantitative phase tomography with micrometer resolution using hard synchrotron radiation x rays. Appl Phys Lett 1999;75(19):2912–2914. https://doi.org/10.1063/1.125225 .
Bronnikov AV. Theory of quantitative phase-contrast computed tomography. J Opt Soc Am A Opt Image Sci Vis 2002;19(3):472–80. https://doi.org/10.1364/josaa.19.000472 .
pubmed: 11876309
Paganin D, Mayo SC, Gureyev TE, Miller PR, Wilkins S. Simultaneous phase and amplitude extraction from a single defocused image of a homogeneous object. J Microsc 2002;206(Pt 1):33–40. https://doi.org/10.1046/j.1365-2818.2002.01010.x .
pubmed: 12000561
Frohn J, Pinkert-Leetsch D, Missbach-Güntner J, Reichardt M, Osterhoff M, Alves F, Salditt T. 3D virtual histology of human pancreatic tissue by multiscale phase-contrast X-ray tomography. J Synchrotron Radiat 2020;27(Pt 6):1707–1719. https://doi.org/10.1107/S1600577520011327 .
pubmed: 33147198
pmcid: 7642968
Gao D, Pogany A, Stevenson AW, Wilkins S. Phase-contrast radiography. Radiographics. 1998;18(5):1257–67. https://doi.org/10.1148/radiographics.18.5.9747618 .
pubmed: 9747618
Bidola PM, Zanette I, Achterhold K, Holzner C, Pfeiffer F. Optimization of propagation-based phase-contrast imaging at a laboratory setup. Opt Express 2015;23(23):30000–13. https://doi.org/10.1364/OE.23.030000 .
pubmed: 26698481
Longo R, Arfelli F, Bellazzini R, Bottigli U, Brez A, Brun F, Brunetti A, Delogu P, Di Lillo F, Dreossi D, Fanti V, Fedon C, Golosio B, Lanconelli N, Mettivier G, Minuti M, Oliva P, Pinchera M, Rigon L, Russo P, Sarno A, Spandre G, Tromba G, Zanconati F. Towards breast tomography with synchrotron radiation at Elettra: first images. Phys Med Biol 2016;61(4): 1634–49. https://doi.org/10.1088/0031-9155/61/4/1634 .
pubmed: 26836274
Brombal L, Golosio B, Arfelli F, Bonazza D, Contillo A, Delogu P, Donato S, Mettivier G, Oliva P, Rigon L, Taibi A, Tromba G, Zanconati F, Longo R. Monochromatic breast computed tomography with synchrotron radiation: phase-contrast and phase-retrieved image comparison and full-volume reconstruction. J Med Imaging (Bellingham) 2019;6(3):031402. https://doi.org/10.1117/1.JMI.6.3.031402 .
Zhao Y, Brun E, Coan P, Huang Z, Sztrókay A, Diemoz PC, Liebhardt S, Mittone A, Gasilov S, Miao J, Bravin A. High-resolution, low-dose phase contrast X-ray tomography for 3D diagnosis of human breast cancers. Proc Natl Acad Sci USA 2012;109(45):18290–4. https://doi.org/10.1073/pnas.1204460109 .
pubmed: 23091003
pmcid: 3494902
Sztrókay A, Diemoz PC, Schlossbauer T, Brun E, Bamberg F, Mayr D, Reiser MF, Bravin A, Coan P. High-resolution breast tomography at high energy: a feasibility study of phase contrast imaging on a whole breast. Phys Med Biol 2012;57(10):2931–42. https://doi.org/10.1088/0031-9155/57/10/2931 .
pubmed: 22516937
Mittone A, Gasilov S, Brun E, Bravin A, Coan P. A single-image method for x-ray refractive index CT. Phys Med Biol 2015;60(9):3433–40. https://doi.org/10.1088/0031-9155/60/9/3433 .
pubmed: 25856228
Grandl S, Sztrókay-Gaul A, Mittone A, Gasilov S, Brun E, Bravin A, Mayr D, Auweter SD, Hellerhoff K, Reiser M, Coan P. Detection of post-therapeutic effects in breast carcinoma using hard X-ray index of refraction computed tomography - a feasibility study. PLoS One 2016;11(6): e0158306. https://doi.org/10.1371/journal.pone.0158306 .
pubmed: 27362638
pmcid: 4928822
Hagen CK, Diemoz PC, Endrizzi M, Rigon L, Dreossi D, Arfelli F, Lopez FC, Longo R, Olivo A. Theory and preliminary experimental verification of quantitative edge illumination x-ray phase contrast tomography. Opt Express 2014;22(7):7989–8000. https://doi.org/10.1364/OE.22.007989 .
pubmed: 24718174
Olivo A, Gkoumas S, Endrizzi M, Hagen CK, Szafraniec MB, Diemoz PC, Munro PR, Ignatyev K, Johnson B, Horrocks JA, Vinnicombe SJ, Jones JL, Speller R. Low-dose phase contrast mammography with conventional x-ray sources. Med Phys 2013;40(9):090701. https://doi.org/10.1118/1.481748 .
pubmed: 24007133
Hagen CK, Munro PR, Endrizzi M, Diemoz PC, Olivo A. Low-dose phase contrast tomography with conventional x-ray sources. Med Phys 2014;41(7):070701. https://doi.org/10.1118/1.4884297 .
pubmed: 24989369
Kashyap Y, Wang H, Sawhney K. Experimental comparison between speckle and grating-based imaging technique using synchrotron radiation X-rays. Opt Express 2016;24(16):18664–73. https://doi.org/10.1364/OE.24.018664 .
pubmed: 27505829
Zdora MC, Zanette I, Walker T, Phillips NW, Smith R, Deyhle H, Ahmed S, Thibault P. X-ray phase imaging with the unified modulated pattern analysis of near-field speckles at a laboratory source. Appl Opt 2020;59(8):2270–2275. https://doi.org/10.1364/AO.384531 .
pubmed: 32225757
Zhou T, Zanette I, Zdora MC, Lundström U, Larsson DH, Hertz HM, Pfeiffer F, Burvall A. Speckle-based x-ray phase-contrast imaging with a laboratory source and the scanning technique. Opt Lett 2015;40(12):2822–5. https://doi.org/10.1364/OL.40.002822 .
pubmed: 26076271
Zdora CM, Thibault P, Kuo W, Fernandez V, Deyhle H, Vila-Comamala J, Olbinado M, Rack A, Lackie P, Katsamenis O, Lawson M, Kurtcuoglu V, Rau C, Pfeiffer F, Zanette I. X-ray phase tomography with near-field speckles for three-dimensional virtual histology. Optica 2020;7:1221–1227. https://doi.org/10.1364/OPTICA.399421 .
Wang H., Kashyap Y, Sawhney K. Quantitative X-ray dark-field and phase tomography using single directional speckle scanning technique. Appl Phys Lett 2016;124102:108. https://doi.org/10.1063/1.4944462 .
Bérujon S, Ziegler E. X-ray multimodal tomography using speckle-vector tracking. Phys Rev Appl 2016;5(4):044014. https://doi.org/10.1103/PhysRevApplied.5.044014 .
Madabhushi A, Lee G. Image analysis and machine learning in digital pathology: challenges and opportunities. Med Image Anal 2016;33:170–175. https://doi.org/10.1016/j.media.2016.06.037 .
pubmed: 27423409
pmcid: 5556681
Jin YW, Jia S, Ashraf AB, Hu P. Integrative data augmentation with u-net segmentation masks improves detection of lymph node metastases in breast cancer patients. Cancers (Basel) 2020;12(10):2934. https://doi.org/10.3390/cancers12102934 .
Muñoz-Aguirre M, Ntasis VF, Rojas S, Guigó R. 2020. PyHIST: a histological image segmentation tool, Vol. 16. https://doi.org/10.1371/journal.pcbi.1008349 .
Taba ST, Gureyev TE, Alakhras M, Lewis S, Lockie D, Brennan PC. X-Ray phase-contrast technology in breast imaging: principles, options, and clinical application. AJR Am J Roentgenol 2018;211(1):133–145. https://doi.org/10.2214/AJR.17.19179 .
pubmed: 29792739
Heck L, Herzen J. Recent advances in X-ray imaging of breast tissue: From two- to three-dimensional imaging. Phys Med 2020;79:69–79. https://doi.org/10.1016/j.ejmp.2020.10.025 .
pubmed: 33171371
Kagias M, Cartier S, Wang Z, Bergamaschi A, Dinapoli R, Mozzanica A, Schmitt B, Stampanoni M. Singleshot x-ray phase contrast imaging using a direct conversion microstrip detector with single photon sensitivity. Appl Phys Lett 2016;234102:108. https://doi.org/10.1063/1.4948584 .
Wen HH, Gomella AA, Patel A, Lynch SK, Morgan NY, Anderson SA, Bennett EE, Xiao X, Liu C, Wolfe DE. Subnanoradian X-ray phase-contrast imaging using a far-field interferometer of nanometric phase gratings. Nat Commun 2013;4:2659. https://doi.org/10.1038/ncomms3659 .
pubmed: 24189696
Miao H, Gomella AA, Chedid N, Chen L, Wen HH. Fabrication of 200 nm period hard X-ray phase gratings. Nano Lett 2014;14(6):3453–8. https://doi.org/10.1021/nl5009713 .
pubmed: 24845537
pmcid: 4055044
Miao H, Gomella AA, Harmon KJ, Bennett EE, Chedid N, Znati S, Panna A, Foster BA, Bhandarkar P, Wen HH. Enhancing tabletop X-ray phase contrast imaging with nano-fabrication. Sci Rep 2015;5:13581. https://doi.org/10.1038/srep13581 .
pubmed: 26315891
pmcid: 4551996