The second pregnancy has no effect in the incidence of macrosomia: a cross-sectional survey in two western Chinese regions.


Journal

Journal of health, population, and nutrition
ISSN: 2072-1315
Titre abrégé: J Health Popul Nutr
Pays: Bangladesh
ID NLM: 100959228

Informations de publication

Date de publication:
13 04 2021
Historique:
received: 09 11 2018
accepted: 31 03 2021
entrez: 14 4 2021
pubmed: 15 4 2021
medline: 7 10 2021
Statut: epublish

Résumé

After the implementation of the universal two-child policy in China, the increase in parity has led to an increase in adverse pregnancy outcomes. The impact of one and two fetuses on the incidence of fetal macrosomia has not been fully confirmed in China. This study aimed to explore the differences in the incidence of fetal macrosomia in first and second pregnancies in Western China after the implementation of the universal two-child policy. A total of 1598 pregnant women from three hospitals were investigated by means of a cross-sectional study from August 2017 to January 2018. Participants were recruited by convenience and divided into first and second pregnancy groups. These groups included 1094 primiparas and 504 women giving birth to their second child. Univariate and multivariate logistic regression analyses were performed to discuss the differences in the incidence of fetal macrosomia in first and second pregnancies. No significant difference was found in the incidence of macrosomia in the first pregnancy group (7.2%) and the second pregnancy group (7.1%). In the second-time pregnant mothers, no significant association was found between the macrosomia of the second child (5.5%) and that of the first child (4.7%). The multivariate logistic regression model showed that mothers older than 30 years are not likely to give birth to children with macrosomia (odds ratio (OR) 0.6, 95% confidence interval (CI) 0.4,0.9). The incidence of macrosomia in Western China is might not be affected by the birth of the second child and is not increased by low parity.

Sections du résumé

BACKGROUND
After the implementation of the universal two-child policy in China, the increase in parity has led to an increase in adverse pregnancy outcomes. The impact of one and two fetuses on the incidence of fetal macrosomia has not been fully confirmed in China. This study aimed to explore the differences in the incidence of fetal macrosomia in first and second pregnancies in Western China after the implementation of the universal two-child policy.
METHODS
A total of 1598 pregnant women from three hospitals were investigated by means of a cross-sectional study from August 2017 to January 2018. Participants were recruited by convenience and divided into first and second pregnancy groups. These groups included 1094 primiparas and 504 women giving birth to their second child. Univariate and multivariate logistic regression analyses were performed to discuss the differences in the incidence of fetal macrosomia in first and second pregnancies.
RESULTS
No significant difference was found in the incidence of macrosomia in the first pregnancy group (7.2%) and the second pregnancy group (7.1%). In the second-time pregnant mothers, no significant association was found between the macrosomia of the second child (5.5%) and that of the first child (4.7%). The multivariate logistic regression model showed that mothers older than 30 years are not likely to give birth to children with macrosomia (odds ratio (OR) 0.6, 95% confidence interval (CI) 0.4,0.9).
CONCLUSIONS
The incidence of macrosomia in Western China is might not be affected by the birth of the second child and is not increased by low parity.

Identifiants

pubmed: 33849665
doi: 10.1186/s41043-021-00244-z
pii: 10.1186/s41043-021-00244-z
pmc: PMC8045374
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

19

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Auteurs

Li Luo (L)

School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China.
Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China.
Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, China.
Chengdu Center for Disease Control and Prevention, 610041, Chengdu, China.

Huan Zeng (H)

School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China.
Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China.
Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, China.

Mao Zeng (M)

School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China.
Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China.
Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, China.

Xueqing Liu (X)

School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China.

Xianglong Xu (X)

School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China.
Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China.
Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, China.
Chengdu Center for Disease Control and Prevention, 610041, Chengdu, China.
Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, 3800, Melbourne, Australia.

Lianlian Wang (L)

Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, 3800, Melbourne, Australia. llian_w@163.com.
The Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, 400016, Chongqing, China. llian_w@163.com.
Department of Reproduction Health and Infertility, The First Affiliated Hospital of Chongqing Medical University, 400016, Chongqing, China. llian_w@163.com.
Canada-China-New Zealand Joint Laboratory of Maternal and Fetal Medicine, Chongqing Medical University, 400016, Chongqing, China. llian_w@163.com.

Yong Zhao (Y)

School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China. zhaoyong@cqmu.edu.cn.
Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China. zhaoyong@cqmu.edu.cn.
Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, China. zhaoyong@cqmu.edu.cn.

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