Cardiolipin enhances the enzymatic activity of cytochrome bd and cytochrome bo


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
13 04 2021
Historique:
received: 16 07 2020
accepted: 25 03 2021
entrez: 14 4 2021
pubmed: 15 4 2021
medline: 5 11 2021
Statut: epublish

Résumé

Cardiolipin (CL) is a lipid that is found in the membranes of bacteria and the inner membranes of mitochondria. CL can increase the activity of integral membrane proteins, in particular components of respiratory pathways. We here report that CL activated detergent-solubilized cytochrome bd, a terminal oxidase from Escherichia coli. CL enhanced the oxygen consumption activity ~ twofold and decreased the apparent K

Identifiants

pubmed: 33850195
doi: 10.1038/s41598-021-87354-0
pii: 10.1038/s41598-021-87354-0
pmc: PMC8044227
doi:

Substances chimiques

Cytochrome b Group 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8006

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Auteurs

Amer H Asseri (AH)

Department of Molecular Cell Biology, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.

Albert Godoy-Hernandez (A)

Department of Biotechnology, Delft University of Technology, Van der Maasweg 9, 2629 HZ, Delft, The Netherlands.

Hojjat Ghasemi Goojani (HG)

Department of Molecular Cell Biology, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.

Holger Lill (H)

Department of Molecular Cell Biology, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.

Junshi Sakamoto (J)

Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Kawazu 680-4, Iizuka, Fukuoka-ken, 820-8502, Japan.

Duncan G G McMillan (DGG)

Department of Biotechnology, Delft University of Technology, Van der Maasweg 9, 2629 HZ, Delft, The Netherlands. D.G.G.McMillan@tudelft.nl.

Dirk Bald (D)

Department of Molecular Cell Biology, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands. d.bald@vu.nl.

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