Intramedullary spinal cord metastasis of gastric cancer.
Adenocarcinoma
gastric cancer
intramedullary metastasis
paraparesis
spinal cord
Journal
Journal of craniovertebral junction & spine
ISSN: 0974-8237
Titre abrégé: J Craniovertebr Junction Spine
Pays: India
ID NLM: 101536746
Informations de publication
Date de publication:
Historique:
received:
01
10
2020
accepted:
22
12
2020
entrez:
14
4
2021
pubmed:
15
4
2021
medline:
15
4
2021
Statut:
ppublish
Résumé
The incidence of intramedullary spinal cord metastasis (ISCM) has been increasing because the overall survival of patients with cancer has improved thanks to recent advanced therapies, such as molecular targeted drugs, anticancer agents, and various irradiation techniques. ISCM from lung and breast cancer is the most common form among cases of ISCM. We report an extremely rare form of ISCM from gastric cancer. This 83-year-old man who had a past medical history of gastric adenocarcinoma presented with acute onset of paraparesis. Spinal magnetic resonance imaging revealed an intramedullary lesion at the upper thoracic level. Due to rapid worsening of his paresis, we decided to perform tumor extirpation. Gross total resection of the tumor was successfully performed. Pathological examination revealed poorly differentiated adenocarcinoma, suggesting the diagnosis of ISCM from gastric cancer. He demonstrated gradual improvement of paraparesis soon after surgery, although his overall survival was limited to about 6 months after surgery. When examining the etiology of acute paraparesis in elderly patients with a past medical history of cancer, ISCM should be considered in the differential diagnosis. The prognosis of ISCM from gastric cancer is still extremely limited. Unfortunately, there is currently no treatment with proven efficacy. Surgery for ISCM from gastric cancer, although a challenging procedure for spine surgeons, should be considered as a therapeutic option in these patients.
Identifiants
pubmed: 33850386
doi: 10.4103/jcvjs.JCVJS_163_20
pii: JCVJS-12-77
pmc: PMC8035591
doi:
Types de publication
Case Reports
Langues
eng
Pagination
77-80Informations de copyright
Copyright: © 2021 Journal of Craniovertebral Junction and Spine.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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