Myelofibrosis and Pancytopenia Associated With Primary Hyperparathyroidism.
PHPT, primary hyperparathyroidism
PTH, parathyroid hormone
hypercalcemia
pancytopenia
primary hyperparathyroidism
refractory anemia
Journal
AACE clinical case reports
ISSN: 2376-0605
Titre abrégé: AACE Clin Case Rep
Pays: United States
ID NLM: 101670593
Informations de publication
Date de publication:
Historique:
entrez:
14
4
2021
pubmed:
15
4
2021
medline:
15
4
2021
Statut:
epublish
Résumé
Primary hyperparathyroidism (PHPT) has varied clinical presentations. Hematologic abnormalities secondary to PHPT have been described before. However, pancytopenia as the initial presentation has rarely been reported. We report a patient with PHPT who presented for evaluation of pancytopenia. Histopathology of the bone marrow at presentation is described. Bone biochemistry results and the hematologic profile before and after curative parathyroidectomy are presented. A 48-year-old woman presented with pancytopenia (hemoglobin, 6.3 g/dL; total leucocyte count, 3000 cells/mm Pancytopenia may be a rare manifestation of PHPT. Thus, it may be prudent to evaluate the calcium profile in patients with chronic refractory anemia and pancytopenia.
Identifiants
pubmed: 33851024
doi: 10.1016/j.aace.2020.11.018
pii: S2376-0605(20)31019-1
pmc: PMC7924162
doi:
Types de publication
Case Reports
Langues
eng
Pagination
69-71Informations de copyright
© 2020 AACE. Published by Elsevier Inc.
Références
J Postgrad Med. 2010 Apr-Jun;56(2):79-84
pubmed: 20622385
Nephron. 1996;72(4):683-7
pubmed: 8730443
Med Hypotheses. 2000 Feb;54(2):236-8
pubmed: 10790758
Clin Endocrinol (Oxf). 2009 Apr;70(4):527-32
pubmed: 18727711
J Clin Invest. 1981 May;67(5):1263-9
pubmed: 7229028
Eur J Pediatr. 1999 Oct;158(10):828-9
pubmed: 10486086
Ann Saudi Med. 2005 Jan-Feb;25(1):29-35
pubmed: 15822491
N Engl J Med. 1993 Jan 21;328(3):171-5
pubmed: 8417383
J Clin Endocrinol Metab. 2012 May;97(5):1420-2
pubmed: 22419706
Indian J Endocrinol Metab. 2015 Sep-Oct;19(5):691-2
pubmed: 26425486
Pathology. 2017 Apr;49(3):326-329
pubmed: 28267996