Norepinephrine-Induced Peripheral Ischemia Leading to Gangrene: A Case Series.
Journal
Advances in skin & wound care
ISSN: 1538-8654
Titre abrégé: Adv Skin Wound Care
Pays: United States
ID NLM: 100911021
Informations de publication
Date de publication:
01 May 2021
01 May 2021
Historique:
entrez:
14
4
2021
pubmed:
15
4
2021
medline:
4
11
2021
Statut:
ppublish
Résumé
Norepinephrine is used in the acute care setting to establish and maintain hemodynamic stability in patients with hypotension. Although it is often a lifesaving medication, norepinephrine may lead to profound vascular insufficiency in the extremities, resulting in dry gangrene and skin necrosis. The purpose of this article is to present a case series of skin complications related to treatment with norepinephrine and review the pathophysiology behind these complications. The authors also explore risk stratification as it relates to history and clinical presentation with subsequent focus on contingencies to mitigate the adverse effects of vasoconstriction on peripheral tissues.
Identifiants
pubmed: 33852464
doi: 10.1097/01.ASW.0000741528.49437.2c
pii: 00129334-202105000-00009
doi:
Substances chimiques
Vasoconstrictor Agents
0
Norepinephrine
X4W3ENH1CV
Types de publication
Journal Article
Langues
eng
Pagination
273-277Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
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