Changes in Body Composition and Cardiometabolic Health After Detraining in Older Men with Osteosarcopenia: 6-Month Follow-Up of the Randomized Controlled Franconian Osteopenia and Sarcopenia Trial (FrOST) Study.
Abdominal Fat
Absorptiometry, Photon
Aged
Aged, 80 and over
Body Composition
Bone Density
Bone Diseases, Metabolic
/ complications
COVID-19
/ epidemiology
Exercise
/ physiology
Follow-Up Studies
Humans
Independent Living
Male
Metabolic Syndrome
/ physiopathology
Obesity
/ complications
Resistance Training
SARS-CoV-2
Sarcopenia
/ complications
body fat
detraining
lean body mass
metabolic syndrome
older men
resistance exercise
Journal
Clinical interventions in aging
ISSN: 1178-1998
Titre abrégé: Clin Interv Aging
Pays: New Zealand
ID NLM: 101273480
Informations de publication
Date de publication:
2021
2021
Historique:
received:
31
12
2020
accepted:
20
02
2021
entrez:
15
4
2021
pubmed:
16
4
2021
medline:
27
4
2021
Statut:
epublish
Résumé
Temporary cessation of exercise but maintenance of habitual physical activity might be a frequent situation in older people's lives. Particularly the COVID-19 induced lockdown of exercise training facilities with individual outdoor activities still being allowed might be a blueprint for this potentially harmful scenario. Thus, the aim of the present study was to determine the effects of 6 months of detraining after 18 months of high-intensity resistance exercise (HIT-RT) on body composition and cardiometabolic outcomes in predominately obese older men with osteosarcopenia. Community-dwelling predominately obese men 72-91 years old with low muscle and bone mass (n=43) were randomly assigned to an 18-month HIT-RT (EG: n=21) or a non-training control group (CG, n=22). After the intervention, participants of the EG discontinued HIT-RT for 6 months, but increased their habitual physical activity. Study outcomes were group differences in detraining changes ("effects") for lean body mass (LBM), total and abdominal body fat rate (determined by dual-energy x-ray absorptiometry) and the Metabolic Syndrome Z-Score (MetSZ). We applied an intention-to-treat analysis with multiple imputation to analyze the data. After the 18-month HIT-RT, we observed significant positive training effects for LBM, total and abdominal body fat rate and the MetSZ (all p<0.001). Abrupt cessation of HIT-RT for 6 months resulted in significantly higher unfavorable changes in the HIT-RT compared with the CG for LBM (p=0.001), total body fat (p=0.003) and the MetSZ (p=0.003), apart from abdominal body fat (p=0.059). However, significant overall effects were still present after 24 months for LBM and body fat indices but not for the MetSZ. The present study clearly indicates the unfavorable effects of 6 months of detraining after HIT-RT. Correspondingly, exercise protocols particularly for older people should focus on continuous exercise with short regeneration periods rather than on intermitted protocols with pronounced training breaks.
Identifiants
pubmed: 33854307
doi: 10.2147/CIA.S299867
pii: 299867
pmc: PMC8039436
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
571-582Informations de copyright
© 2021 Kemmler et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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