Comparison of 18F-sodium fluoride positron emission tomography and CT: An exploratory study in 12 dogs with elbow pain.
bone
elbow dysplasia
joint
medial coronoid process
standardized uptake value
Journal
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
ISSN: 1740-8261
Titre abrégé: Vet Radiol Ultrasound
Pays: England
ID NLM: 9209635
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
revised:
29
12
2020
received:
04
08
2020
accepted:
29
01
2021
pubmed:
16
4
2021
medline:
16
7
2021
entrez:
15
4
2021
Statut:
ppublish
Résumé
18F-Sodium Fluoride (18F-NaF) positron emission tomography (PET) provides high resolution functional information about bone activity and can be fused with CT images to improve three-dimensional localization and characterization of lesions. This prospective, observational study assessed 18F-NaF PET-CT for imaging of canine elbows, compared PET with CT findings, and assessed correlation with lameness. Twelve patients with elbow pain were included. Cases included primarily young, large breed dogs. A three-level clinical lameness score was assigned to each forelimb. All dogs had bilateral elbow joints imaged with CT and PET under general anesthesia, approximately 1.5 h after intravenous injection of 3 MBq/kg of 18F-NaF. Imaging findings were independently reviewed by two radiologists using a three-level scoring scheme over nine anatomical regions in the elbow. PET imaging identified areas of bone activity where minimal change was identified on CT. PET imaging also demonstrated absence of uptake in areas where modeling was present on CT. A stronger correlation was observed between clinical grades and PET scores (r
Substances chimiques
Fluorine Radioisotopes
0
Fluorine-18
GZ5I74KB8G
Sodium Fluoride
8ZYQ1474W7
Types de publication
Comparative Study
Journal Article
Observational Study, Veterinary
Langues
eng
Sous-ensembles de citation
IM
Pagination
498-506Subventions
Organisme : Center for Companion Animal Health, UC Davis
Informations de copyright
© 2021 American College of Veterinary Radiology.
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