Off-label use of anti-IL-1 drugs in rheumatic diseases.
anakinra
anti IL-1
canakinumab
off-label use
rheumatic diseases
Journal
International journal of immunopathology and pharmacology
ISSN: 2058-7384
Titre abrégé: Int J Immunopathol Pharmacol
Pays: England
ID NLM: 8911335
Informations de publication
Date de publication:
Historique:
entrez:
15
4
2021
pubmed:
16
4
2021
medline:
19
11
2021
Statut:
ppublish
Résumé
Interleukin-1 (IL-1) plays a key role in the pathogenesis of different rheumatic diseases. There are now several agents available on the market capable of blocking IL-1. The proven effectiveness and excellent safety of these drugs makes them a possible therapeutic option in the treatment of IL-1 driven diseases, when previous therapies are contraindicated or ineffective. This article discusses the European wide off-label use of these drugs for the treatment of rheumatic diseases.
Identifiants
pubmed: 33855881
doi: 10.1177/20587384211006584
pmc: PMC8056561
doi:
Substances chimiques
Antirheumatic Agents
0
Interleukin-1
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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