Residential radon and lung cancer characteristics at diagnosis.


Journal

International journal of radiation biology
ISSN: 1362-3095
Titre abrégé: Int J Radiat Biol
Pays: England
ID NLM: 8809243

Informations de publication

Date de publication:
2021
Historique:
pubmed: 16 4 2021
medline: 30 9 2021
entrez: 15 4 2021
Statut: ppublish

Résumé

This study sought to ascertain whether there might be an association between radon concentrations and age, gender, histologic type, and tumor stage at diagnosis. Lung cancer cases from different multicenter case-control studies were analyzed, and clinical data were retrieved from electronic health records and personal interviews. A radon device was placed in all dwellings of participants, and we then tested the existence of an association between residential radon and lung cancer characteristics at diagnosis. Of the total of 829 lung cancer cases included, 56.7% were smokers or ex-smokers. There was no association between indoor radon concentrations and age, gender, histologic type or tumor stage at diagnosis. Median indoor radon concentrations increased with age at diagnosis for men, but not for women. When analyzing participants exposed to more than 1000 Bq/m There seems to be no association between radon and age, gender, histologic type or tumor stage at diagnosis. Higher radon exposure is more frequent in the case of small-cell lung cancer.

Identifiants

pubmed: 33856283
doi: 10.1080/09553002.2021.1913527
doi:

Substances chimiques

Radon Q74S4N8N1G

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

997-1002

Auteurs

María Torres-Durán (M)

Service of Neumology, University Hospital Complex of Vigo, Vigo, Spain.

Ana Casal-Mouriño (A)

Service of Neumology, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.

Alberto Ruano-Ravina (A)

Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain.
Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública, CIBERESP), Madrid, Spain.
Instituto de Investigaciones Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.

Mariano Provencio (M)

Service of Medical Oncology, Puerta del Hierro University Hospital, Madrid, Spain.

Isaura Parente-Lamelas (I)

Service of Neumology, University Hospital Complex of Ourense, Ourense, Spain.

Jesús Hernández-Hernández (J)

Service of Neumology, Complejo Asistencial de Ávila, Ávila, Spain.

Iria Vidal-García (I)

Service of Neumology, University Hospital of A Coruña, A Coruña, Spain.

Leonor Varela-Lema (L)

Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain.
Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública, CIBERESP), Madrid, Spain.
Instituto de Investigaciones Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.

Luis Valdés Cuadrado (L)

Service of Neumology, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.

Alberto Fernández-Villar (A)

Service of Neumology, University Hospital Complex of Vigo, Vigo, Spain.

Juan Barros-Dios (J)

Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain.
Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública, CIBERESP), Madrid, Spain.
Instituto de Investigaciones Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.

Mónica Pérez-Ríos (M)

Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain.
Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública, CIBERESP), Madrid, Spain.
Instituto de Investigaciones Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.

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Classifications MeSH