Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome.
Pneumocystis jirovecii
bronchopulmonary dysplasia
preterm infants
respiratory distress syndrome
vertical transmission
Journal
The Journal of infectious diseases
ISSN: 1537-6613
Titre abrégé: J Infect Dis
Pays: United States
ID NLM: 0413675
Informations de publication
Date de publication:
16 05 2022
16 05 2022
Historique:
received:
03
11
2020
accepted:
14
04
2021
pubmed:
16
4
2021
medline:
20
5
2022
entrez:
15
4
2021
Statut:
ppublish
Résumé
We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns <32 weeks gestation. Molecular and microscopic methods were used for detection of P. jirovecii in patients' specimens. Pneumocystis DNA was detected in 8 nasopharyngeal aspirates (14%) of 56 newborns and in 7 oral washes (21%) of 34 mothers. Pneumocystis detection immediately after birth suggests the possibility of its transplacental transmission. Compared to noncolonized infants, more frequent occurrence of bronchopulmonary dysplasia was seen in colonized infants (P = .02), suggesting a potential clinical importance of this pathogen in abnormal lung development.
Identifiants
pubmed: 33857302
pii: 6226828
doi: 10.1093/infdis/jiab209
pmc: PMC9113508
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1807-1810Informations de copyright
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.
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