The performance of phenomenological models in providing near-term Canadian case projections in the midst of the COVID-19 pandemic: March - April, 2020.


Journal

Epidemics
ISSN: 1878-0067
Titre abrégé: Epidemics
Pays: Netherlands
ID NLM: 101484711

Informations de publication

Date de publication:
06 2021
Historique:
received: 12 05 2020
revised: 20 08 2020
accepted: 13 02 2021
pubmed: 16 4 2021
medline: 16 7 2021
entrez: 15 4 2021
Statut: ppublish

Résumé

The COVID-19 pandemic has had an unprecedented impact on citizens and health care systems globally. Valid near-term projections of cases are required to inform the escalation, maintenance and de-escalation of public health measures, and for short-term health care resource planning. Near-term case and epidemic growth rate projections for Canada were estimated using three phenomenological models: the logistic model, Generalized Richard's model (GRM) and a modified Incidence Decay and Exponential Adjustment (m-IDEA) model. Throughout the COVID-19 epidemic in Canada, these models have been validated against official national epidemiological data on an ongoing basis. The best-fit models estimated that the number of COVID-19 cases predicted to be reported in Canada as of April 1, 2020 and May 1, 2020 would be 11,156 (90 % prediction interval: 9,156-13,905) and 54,745 (90 % prediction interval: 54,252-55,239). The three models varied in their projections and their performance over the first seven weeks of their implementation. Both the logistic model and GRM under-predicted cases reported a week following the projection date in nearly all instances. The logistic model performed best at the early stages, the m-IDEA model performed best at the later stages, and the GRM performed most consistently during the full period assessed. All three models have yielded qualitatively comparable near-term forecasts of cases and epidemic growth for Canada. Under or over-estimation of projected cases and epidemic growth by these models could be associated with changes in testing policies and/or public health measures. Simple forecasting models can be invaluable in projecting the changes in trajectory of subsequent waves of cases to provide timely information to support the pandemic response.

Sections du résumé

BACKGROUND
The COVID-19 pandemic has had an unprecedented impact on citizens and health care systems globally. Valid near-term projections of cases are required to inform the escalation, maintenance and de-escalation of public health measures, and for short-term health care resource planning.
METHODS
Near-term case and epidemic growth rate projections for Canada were estimated using three phenomenological models: the logistic model, Generalized Richard's model (GRM) and a modified Incidence Decay and Exponential Adjustment (m-IDEA) model. Throughout the COVID-19 epidemic in Canada, these models have been validated against official national epidemiological data on an ongoing basis.
RESULTS
The best-fit models estimated that the number of COVID-19 cases predicted to be reported in Canada as of April 1, 2020 and May 1, 2020 would be 11,156 (90 % prediction interval: 9,156-13,905) and 54,745 (90 % prediction interval: 54,252-55,239). The three models varied in their projections and their performance over the first seven weeks of their implementation. Both the logistic model and GRM under-predicted cases reported a week following the projection date in nearly all instances. The logistic model performed best at the early stages, the m-IDEA model performed best at the later stages, and the GRM performed most consistently during the full period assessed.
CONCLUSIONS
All three models have yielded qualitatively comparable near-term forecasts of cases and epidemic growth for Canada. Under or over-estimation of projected cases and epidemic growth by these models could be associated with changes in testing policies and/or public health measures. Simple forecasting models can be invaluable in projecting the changes in trajectory of subsequent waves of cases to provide timely information to support the pandemic response.

Identifiants

pubmed: 33857889
pii: S1755-4365(21)00017-7
doi: 10.1016/j.epidem.2021.100457
pii:
doi:

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

100457

Informations de copyright

Crown Copyright © 2021. Published by Elsevier B.V. All rights reserved.

Auteurs

Ben A Smith (BA)

Infectious Disease Prevention and Control Branch, Public Health Agency of Canada, 370 Speedvale Ave W., Guelph, ON, N1H 7M7, Canada. Electronic address: ben.smith@canada.ca.

Christina Bancej (C)

Infectious Disease Prevention and Control Branch, Public Health Agency of Canada, 130 Colonnade R., Ottawa, ON, K1A 0K9, Canada.

Aamir Fazil (A)

Infectious Disease Prevention and Control Branch, Public Health Agency of Canada, 370 Speedvale Ave W., Guelph, ON, N1H 7M7, Canada.

Muhammad Mullah (M)

Infectious Disease Prevention and Control Branch, Public Health Agency of Canada, 130 Colonnade R., Ottawa, ON, K1A 0K9, Canada.

Ping Yan (P)

Infectious Disease Prevention and Control Branch, Public Health Agency of Canada, 130 Colonnade R., Ottawa, ON, K1A 0K9, Canada.

Shenghai Zhang (S)

Infectious Disease Prevention and Control Branch, Public Health Agency of Canada, 130 Colonnade R., Ottawa, ON, K1A 0K9, Canada.

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