Cardioprotective potential of indol-3-carbinol against high salt induced myocardial stress and hypertrophy in Sprague dawley rats besides molecular docking on muscarinic receptor-2.

Animals Blood Pressure Hypertrophy Male Methanol Molecular Docking Simulation Rats Rats, Sprague-Dawley Receptors, Muscarinic
Indol-3-carbinol cardioprotective high salt hypertrophy molecular docking myocardial stress

Journal

Natural product research
ISSN: 1478-6427
Titre abrégé: Nat Prod Res
Pays: England
ID NLM: 101167924

Informations de publication

Date de publication:
May 2022
Historique:
pubmed: 17 4 2021
medline: 3 6 2022
entrez: 16 4 2021
Statut: ppublish

Résumé

The vegetative chemical constituent, indol-3-carbinol (I-3-C) studied for its cardioprotective potential in male Sprague dawley rats. The I-3-C at 20 mg/Kg b.w, p.o significantly (

Identifiants

DOI: 10.1080/14786419.2021.1912042 PMID: 33858276
pubmed: 33858276
doi: 10.1080/14786419.2021.1912042
doi:

Substances chimiques

Receptors, Muscarinic 0
Methanol Y4S76JWI15

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2610-2614

Auteurs

Sudheer Akkiraju (S)

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Anantapur, Andhra Pradesh, India.

Somasekhar Reddy Kanala (SR)

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Anantapur, Andhra Pradesh, India.

Sardip Khatri (S)

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Anantapur, Andhra Pradesh, India.

Vinay Kumar Kutagulla (VK)

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Anantapur, Andhra Pradesh, India.

Vijayajyothi Mallela (V)

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Anantapur, Andhra Pradesh, India.

Ramalingam Peraman (R)

RERDS-Centre for Pharmaceutical Research, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) Campus, Anantapur, Andhra Pradesh, India.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Cardioprotective potential of indol-3-carbinol...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Hémodynamique › Pression sanguine › Cardioprotective potential of indol-3-carbinol...
questionsmedicales.fr › États, signes et symptômes pathologiques › États anatomopathologiques › Hypertrophie › Cardioprotective potential of indol-3-carbinol...
questionsmedicales.fr › Composés chimiques organiques › Alcools › Méthanol › Cardioprotective potential of indol-3-carbinol...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Cardioprotective potential of indol-3-carbinol...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Cardioprotective potential of indol-3-carbinol...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Sprague-Dawley › Cardioprotective potential of indol-3-carbinol...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs cholinergiques › Récepteur muscarinique › Cardioprotective potential of indol-3-carbinol...