Paraproteinemias and Peripheral Nerve Disease.

Aged Humans Monoclonal Gammopathy of Undetermined Significance Paraproteinemias / diagnosis Peripheral Nervous System Diseases / diagnosis Waldenstrom Macroglobulinemia
Amyloidosis Neuropathy Paraproteinemia Peripheral nerve disease

Journal

Clinics in geriatric medicine
ISSN: 1879-8853
Titre abrégé: Clin Geriatr Med
Pays: United States
ID NLM: 8603766

Informations de publication

Date de publication:
05 2021
Historique:
entrez: 16 4 2021
pubmed: 17 4 2021
medline: 18 9 2021
Statut: ppublish

Résumé

This article provides an overview of the clinical features, diagnosis, and treatment of the major paraprotein-related peripheral neuropathies, including monoclonal gammopathy of undetermined significance, Waldenström macroglobulinemia, POEMS syndrome, multiple myeloma, transthyretin amyloidosis, and light chain amyloidosis. For each paraprotein neuropathy, the epidemiology, demographics, systemic findings, and electrophysiologic features are presented. Pharmacologic treatment of transthyretin amyloid polyneuropathy also is reviewed.

Identifiants

DOI: 10.1016/j.cger.2021.01.004 PMID: 33858612
pubmed: 33858612
pii: S0749-0690(21)00004-5
doi: 10.1016/j.cger.2021.01.004
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

301-312

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Yaowaree Leavell (Y)

Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Susan C Shin (SC)

Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: susan.shin@mssm.edu.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Paraproteinemias and Peripheral Nerve Disease.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Paraproteinemias and Peripheral Nerve Disease.
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Paraprotéinémies › Gammapathie monoclonale de signification indéterminée › Paraproteinemias and Peripheral Nerve Disease.
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Paraprotéinémies › Paraproteinemias and Peripheral Nerve Disease.
questionsmedicales.fr › Maladies du système nerveux › Maladies neuromusculaires › Neuropathies périphériques › Paraproteinemias and Peripheral Nerve Disease.
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Paraprotéinémies › Macroglobulinémie de Waldenström › Paraproteinemias and Peripheral Nerve Disease.