Subnational estimates of factors associated with under-five mortality in Kenya: a spatio-temporal analysis, 1993-2014.

child health epidemiology geographic information systems health services research indices of health and disease and standardisation of rates

Journal

BMJ global health
ISSN: 2059-7908
Titre abrégé: BMJ Glob Health
Pays: England
ID NLM: 101685275

Informations de publication

Date de publication:
04 2021
Historique:
received: 24 11 2020
revised: 26 03 2021
accepted: 27 03 2021
entrez: 16 4 2021
pubmed: 17 4 2021
medline: 25 6 2021
Statut: ppublish

Résumé

To improve child survival, it is necessary to describe and understand the spatial and temporal variation of factors associated with child survival beyond national aggregates, anchored at decentralised health planning units. Therefore, we aimed to provide subnational estimates of factors associated with child survival while elucidating areas of progress, stagnation and decline in Kenya. Twenty household surveys and three population censuses conducted since 1989 were assembled and spatially aligned to 47 subnational Kenyan county boundaries. Bayesian spatio-temporal Gaussian process regression models accounting for inadequate sample size and spatio-temporal relatedness were fitted for 43 factors at county level between 1993 and 2014. Nationally, the coverage and prevalence were highly variable with 38 factors recording an improvement. The absolute percentage change (1993-2014) was heterogeneous ranging between 1% and 898%. At the county level, the estimates varied across space and over time with a majority showing improvements after 2008 which was preceded by a period of deterioration (late-1990 to early-2000). Counties in Northern Kenya were consistently observed to have lower coverage of interventions and remained disadvantaged in 2014 while areas around Central Kenya had and historically have had higher coverage across all intervention domains. Most factors in Western and South-East Kenya recorded moderate intervention coverage although having a high infection prevalence of both HIV and malaria. The heterogeneous estimates necessitates prioritisation of the marginalised counties to achieve health equity and improve child survival uniformly across the country. Efforts are required to narrow the gap between counties across all the drivers of child survival. The generated estimates will facilitate improved benchmarking and establish a baseline for monitoring child development goals at subnational level.

Sections du résumé

BACKGROUND
To improve child survival, it is necessary to describe and understand the spatial and temporal variation of factors associated with child survival beyond national aggregates, anchored at decentralised health planning units. Therefore, we aimed to provide subnational estimates of factors associated with child survival while elucidating areas of progress, stagnation and decline in Kenya.
METHODS
Twenty household surveys and three population censuses conducted since 1989 were assembled and spatially aligned to 47 subnational Kenyan county boundaries. Bayesian spatio-temporal Gaussian process regression models accounting for inadequate sample size and spatio-temporal relatedness were fitted for 43 factors at county level between 1993 and 2014.
RESULTS
Nationally, the coverage and prevalence were highly variable with 38 factors recording an improvement. The absolute percentage change (1993-2014) was heterogeneous ranging between 1% and 898%. At the county level, the estimates varied across space and over time with a majority showing improvements after 2008 which was preceded by a period of deterioration (late-1990 to early-2000). Counties in Northern Kenya were consistently observed to have lower coverage of interventions and remained disadvantaged in 2014 while areas around Central Kenya had and historically have had higher coverage across all intervention domains. Most factors in Western and South-East Kenya recorded moderate intervention coverage although having a high infection prevalence of both HIV and malaria.
CONCLUSION
The heterogeneous estimates necessitates prioritisation of the marginalised counties to achieve health equity and improve child survival uniformly across the country. Efforts are required to narrow the gap between counties across all the drivers of child survival. The generated estimates will facilitate improved benchmarking and establish a baseline for monitoring child development goals at subnational level.

Identifiants

pubmed: 33858833
pii: bmjgh-2020-004544
doi: 10.1136/bmjgh-2020-004544
pmc: PMC8054106
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
ID : 212176
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 107769/Z/10/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 103602
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 203077
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 201866/Z/16/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 201866
Pays : United Kingdom
Organisme : EPA
ID : EP-C-15-003
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

Int J Health Geogr. 2020 Oct 13;19(1):41
pubmed: 33050935
PLoS One. 2015 Jun 24;10(6):e0128792
pubmed: 26107772
J Environ Public Health. 2018 Oct 17;2018:5452938
pubmed: 30416526
Sensors (Basel). 2007 Nov 05;7(11):2636-2651
pubmed: 28903251
Int J Equity Health. 2011 May 26;10:22
pubmed: 21612669
Econ Hum Biol. 2017 Feb;24:74-79
pubmed: 27907834
JAMA Netw Open. 2018 Dec 7;1(8):e185152
pubmed: 30646326
AIDS Behav. 2015 Apr;19(4):645-54
pubmed: 25381562
PLoS One. 2014 Oct 31;9(10):e110110
pubmed: 25360758
BMC Health Serv Res. 2020 Jul 18;20(1):665
pubmed: 32682421
Int J Health Geogr. 2009 Mar 06;8:13
pubmed: 19267903
J Nutr. 2003 Nov;133(11 Suppl 2):3875S-4061S
pubmed: 14714275
Public Health Nutr. 2012 Sep;15(9):1715-27
pubmed: 22694984
Nat Commun. 2018 Nov 26;9(1):4994
pubmed: 30478314
JAMA. 2006 Aug 16;296(7):859-62
pubmed: 16905791
PLoS One. 2016 Jan 19;11(1):e0144618
pubmed: 26784957
Int Perspect Sex Reprod Health. 2015 Jun;41(2):69-79
pubmed: 26308259
PLoS One. 2017 Aug 3;12(8):e0182440
pubmed: 28771558
PLoS Med. 2007 Aug;4(8):e255
pubmed: 17713981
BMC Pregnancy Childbirth. 2018 Mar 27;18(1):77
pubmed: 29580207
Soc Sci Med. 1986;22(3):315-9
pubmed: 3961547
Health Inf Manag. 2019 May;48(2):62-75
pubmed: 29898604
Arch Iran Med. 2014 Mar;17(3):189-92
pubmed: 24621362
BMJ Glob Health. 2019 Sep 29;4(5):e001849
pubmed: 31637032
J Epidemiol Glob Health. 2014 Sep;4(3):169-76
pubmed: 25107652
BMC Med. 2015 Dec 14;13:299
pubmed: 26654445
Lancet. 2010 Jun 5;375(9730):1988-2008
pubmed: 20546887
Health Policy. 1995 Apr-Jun;32(1-3):245-55
pubmed: 10156641
BMC Public Health. 2019 Feb 20;19(1):216
pubmed: 30786895
Trop Med Int Health. 2000 Nov;5(11):755-64
pubmed: 11123822
BMC Med. 2015 Apr 02;13:69
pubmed: 25889124
Glob Health Action. 2014 Sep 03;7:24765
pubmed: 25190448
BMC Public Health. 2020 Sep 15;20(1):1407
pubmed: 32933501
BMC Public Health. 2018 Dec 4;18(1):1339
pubmed: 30514269
Malawi Med J. 2012 Sep;24(3):69-71
pubmed: 23638278
Stud Fam Plann. 1991 May-Jun;22(3):131-43
pubmed: 1949097
BMJ Glob Health. 2018 May 02;3(2):e000726
pubmed: 29736273
BMC Med. 2015 Dec 03;13:285
pubmed: 26631048
Sci Data. 2015 Dec 08;2:150066
pubmed: 26646728
Trop Med Int Health. 2003 Oct;8(10):917-26
pubmed: 14516303
AIDS Care. 2010 Jun;22(6):743-50
pubmed: 20461572
BMC Public Health. 2012 Jul 23;12:540
pubmed: 22823923
BMC Public Health. 2018 May 8;18(1):600
pubmed: 29739374
BMC Pediatr. 2014 Jan 13;14:5
pubmed: 24410931
BMC Med. 2018 Dec 4;16(1):226
pubmed: 30509258
Malar J. 2018 Sep 26;17(1):340
pubmed: 30257697
BMC Public Health. 2020 Mar 23;20(1):379
pubmed: 32293367
Lancet. 2019 May 4;393(10183):1843-1855
pubmed: 30961907
Bull World Health Organ. 2017 Oct 01;95(10):683-694
pubmed: 29147041
Vaccine. 2015 Nov 27;33(48):6778-85
pubmed: 26482146
Health Policy Plan. 2019 Mar 1;34(2):120-131
pubmed: 30843068
BMC Public Health. 2016 Feb 16;16:152
pubmed: 26880141
PLoS Med. 2014 Sep 22;11(9):e1001730
pubmed: 25243780
Lancet Glob Health. 2018 Mar;6(3):e342-e350
pubmed: 29396220
BMC Med. 2015 Sep 02;13:208
pubmed: 26329607
Health Policy Plan. 1996 Mar;11(1):52-63
pubmed: 10155878
BMC Public Health. 2019 Jan 31;19(1):135
pubmed: 30704419
Soc Sci Med. 1999 Feb;48(3):301-12
pubmed: 10077278
PLoS One. 2016 Aug 17;11(8):e0161221
pubmed: 27532665
BMC Public Health. 2019 Feb 4;19(1):146
pubmed: 30717714
Int J Environ Res Public Health. 2020 Apr 28;17(9):
pubmed: 32354095
AIDS. 2008 Oct 1;22(15):2019-24
pubmed: 18784464
Glob Health Action. 2016 Nov 07;9:32408
pubmed: 27829489
East Afr Med J. 2012 Apr;89(4):134-41
pubmed: 26856038
Matern Child Nutr. 2019 Jan;15 Suppl 1:e12747
pubmed: 30748118
Int J Equity Health. 2020 Mar 14;19(1):35
pubmed: 32171320
Lancet Glob Health. 2017 Aug;5(8):e782-e795
pubmed: 28716350
Lancet HIV. 2018 May;5(5):e241-e249
pubmed: 29650451
Stud Fam Plann. 2018 Mar;49(1):87-92
pubmed: 29484673
Public Health Nutr. 2012 Jun;15(6):1029-38
pubmed: 22107729
AIDS Behav. 2018 Jul;22(Suppl 1):125-130
pubmed: 29943124
Stud Fam Plann. 2003 Sep;34(3):149-59
pubmed: 14558318
Nature. 2020 Jan;577(7789):231-234
pubmed: 31915393
PLoS One. 2016 Aug 25;11(8):e0162006
pubmed: 27561009
BMJ Glob Health. 2018 Jun 27;3(3):e000904
pubmed: 29989036
Matern Child Nutr. 2019 Jan;15 Suppl 1:e12723
pubmed: 30748122
Health Policy Plan. 1995 Jun;10(2):164-70
pubmed: 10143454
Glob Public Health. 2010;5(6):578-94
pubmed: 20099183
Bull World Health Organ. 2003;81(2):138-9
pubmed: 12751422
Epidemiology. 2018 Jan;29(1):5-7
pubmed: 29053554
JAMA Netw Open. 2019 Sep 4;2(9):e1911318
pubmed: 31517966
J Acquir Immune Defic Syndr. 2010 Jul;54(3):317-23
pubmed: 20453819
Clin Infect Dis. 2020 Jul 11;71(2):372-380
pubmed: 31504308
Malar J. 2007 May 29;6:72
pubmed: 17535417
SAHARA J. 2005 Jul;2(2):244-50
pubmed: 17601006
BMC Med. 2020 Jun 3;18(1):121
pubmed: 32487080
Lancet Glob Health. 2020 Sep;8(9):e1162-e1185
pubmed: 32827479
Nutr J. 2010 Feb 26;9:9
pubmed: 20187960
Am J Trop Med Hyg. 2014 Feb;90(2):234-41
pubmed: 24343886
Bull World Health Organ. 2003;81(2):140-5
pubmed: 12756980
Int J Epidemiol. 2012 Dec;41(6):1602-13
pubmed: 23148108

Auteurs

Peter M Macharia (PM)

Population Health Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya pmacharia@kemri-wellcome.org.

Noel K Joseph (NK)

Population Health Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.

Benn Sartorius (B)

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, USA.

Robert W Snow (RW)

Population Health Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Emelda A Okiro (EA)

Population Health Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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