ZBED6 binding motifs correlate with endogenous retroviruses and

ERV ZBED6 motif syncytin transposon

Journal

Virus evolution
ISSN: 2057-1577
Titre abrégé: Virus Evol
Pays: England
ID NLM: 101664675

Informations de publication

Date de publication:
Jan 2021
Historique:
entrez: 16 4 2021
pubmed: 17 4 2021
medline: 17 4 2021
Statut: epublish

Résumé

Retroviruses have infiltrated vertebrate germlines for millions of years as inherited endogenous retroviruses (ERVs). Mammalian genomes host large numbers of ERVs and transposable elements (TEs), including retrotransposons and DNA transposons, that contribute to genomic innovation and evolution as coopted genes and regulators of diverse functions. To explore features distinguishing coopted ERVs and TEs from other integrations, we focus on the potential role of ZBED6 and repeated ERV domestication as repurposed

Identifiants

pubmed: 33859827
doi: 10.1093/ve/veaa083
pii: veaa083
pmc: PMC8035546
doi:

Types de publication

Journal Article

Langues

eng

Pagination

veaa083

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press.

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Auteurs

Mats E Pettersson (ME)

Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.

Patric Jern (P)

Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.

Classifications MeSH